Identification of microRNA biomarker candidates in urine and plasma from rats with kidney or liver damage
Wolenski, Francis S., Shah, Pooja, Sano, Tomoya, Shinozawa, Tadahiro, Bernard, Hugues, Gallacher, Matt J., Wyllie, Shylah D., Varrone, Georgianna, Cicia, Lisa A., Carsillo, Mary E., Fisher, Craig D., Ottinger, Sean E., Koenig, Erik, Kirby, Patrick J.
Published in Journal of applied toxicology (01.03.2017)
Published in Journal of applied toxicology (01.03.2017)
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Journal Article
The evaluation of drug-induced changes in cardiac inotropy in dogs: Results from a HESI-sponsored consortium
Guth, Brian D., Chiang, Alan Y., Doyle, Jennifer, Engwall, Michael J., Guillon, Jean-Michel, Hoffmann, Peter, Koerner, John, Mittelstadt, Scott, Ottinger, Sean, Pierson, Jennifer Beck, Pugsley, Michael K., Rossman, Eric I., Walisser, Jacqueline, Sarazan, R. Dustan
Published in Journal of pharmacological and toxicological methods (01.09.2015)
Published in Journal of pharmacological and toxicological methods (01.09.2015)
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Increased stress associated with head-out plethysmography testing can exacerbate respiratory effects and lead to mortality in rats
Lynch, James J., Rossignol, Emilie, Moehrle, Joerg J., Van Vleet, Terry R., Marsh, Kennan C., Parman, Toufan, Mirsalis, Jon, Ottinger, Sean E., Segreti, Jason A., Rao, Mohan, Mittelstadt, Scott W.
Published in Journal of pharmacological and toxicological methods (01.09.2019)
Published in Journal of pharmacological and toxicological methods (01.09.2019)
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Journal Article
Deamination of Fumonisin B1 and Biological Assessment of Reaction Product Toxicity
Lemke, Shawna L, Ottinger, Sean E, Ake, Charles L, Mayura, Kittane, Phillips, Timothy D
Published in Chemical research in toxicology (15.01.2001)
Published in Chemical research in toxicology (15.01.2001)
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Journal Article
Integrated nonclinical and clinical risk assessment of the investigational proteasome inhibitor ixazomib on the QTc interval in cancer patients
Gupta, Neeraj, Huh, Yeamin, Hutmacher, Matthew M., Ottinger, Sean, Hui, Ai-Min, Venkatakrishnan, Karthik
Published in Cancer chemotherapy and pharmacology (01.09.2015)
Published in Cancer chemotherapy and pharmacology (01.09.2015)
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A Phase 1 First-in-Human Study of the Anti-CD38 Dimeric Fusion Protein TAK-169 for the Treatment of Patients (pts) with Relapsed or Refractory Multiple Myeloma (RRMM) Who Are Proteasome Inhibitor (PI)- and Immunomodulatory Drug (IMiD)-Refractory, Including Pts Relapsed/Refractory (R/R) or Naïve to Daratumumab (dara)
Kumar, Shaji K., Cornell, Robert F., Landgren, Ola, Ailawadhi, Sikander, Higgins, Jack P, Willert, Erin K, Waltzman, Roger, Lin, Jianchang, Zhang, Yuhong, Lublinsky, Anya R, Dash, Ajeeta B, Hanley, Michael, Manoharan, Divya, Leichter, Morgan, Ottinger, Sean, Labotka, Richard J, Newcomb, John, Vorog, Alexander
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Integrated nonclinical and clinical risk assessment to obviate the need for a dedicated QTc study of ixazomib citrate (MLN9708) in cancer patients (pts)
Gupta, Neeraj, Huh, Yeamin, Hutmacher, Matthew M, Ottinger, Sean, Hui, Ai-Min, Venkatakrishnan, Karthik
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
UTILIZATION OF ELECTROCHEMICALLY GENERATED OZONE IN THE DEGRADATION AND DETOXICATION OF BENZO[a]PYRENE
Ottinger, S E, Mayura, K, Lemke, S L, McKenzie, K S, Wang, N, Kubena, L F, Phillips, T D
Published in Journal of Toxicology and Environmental Health, Part A (27.08.1999)
Published in Journal of Toxicology and Environmental Health, Part A (27.08.1999)
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Journal Article
Identification of microRNA biomarker candidates in urine and plasma from rats with kidney or liver damage: Novel rat microRNA biomarkers
Wolenski, Francis S., Shah, Pooja, Sano, Tomoya, Shinozawa, Tadahiro, Bernard, Hugues, Gallacher, Matt J., Wyllie, Shylah D., Varrone, Georgianna, Cicia, Lisa A., Carsillo, Mary E., Fisher, Craig D., Ottinger, Sean E., Koenig, Erik, Kirby, Patrick J.
Published in Journal of applied toxicology (01.03.2017)
Published in Journal of applied toxicology (01.03.2017)
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Journal Article
A HESI consortium update on cardiac contractility endpoints
Pugsley, Michael K., Guth, Brian, Chiang, Alan, Doyle, Jennifer, Engwall, Mike, Guillon, Jean-Michel, Hoffmann, Peter, Koerner, John, Mittelstadt, Scott, Ottinger, Sean, Pierson, Jennifer, Rossman, Eric, Walisser, Jacqueline, Dustan Sarazan, R.
Published in Journal of pharmacological and toxicological methods (01.09.2016)
Published in Journal of pharmacological and toxicological methods (01.09.2016)
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Journal Article
A preload and lusitropy corrected dP/dtmax-derived index of contractility: Evaluation in telemetered beagle dogs treated with amrinone
Youngblood, Brad, Kloepfer, Pam, Ueyama, Yukie, George, Robbie, Sutayatram, Sai, Hardy, Rebecca, Gallacher, Matt, Ottinger, Sean, Hamlin, Robert, del Rio, Carlos
Published in Journal of pharmacological and toxicological methods (01.11.2014)
Published in Journal of pharmacological and toxicological methods (01.11.2014)
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Journal Article
Health and environmental sciences institute integrated strategies working group: Update on the evaluation of drug-induced changes in the cardiac inotropy in dogs
Engwall, Michael J., Walisser, Jacqueline A., Saul, Jim, Dustan Sarazan, R., Guth, Brian, Market, Michael, Skinner, Matthew, Guillon, Jean-Michel, Ottinger, Sean, Heyen, Jonathan R., Cools, Frank, Hoffmann, Peter K., Rossman, Eric I., Pierson, Jennifer B.
Published in Journal of pharmacological and toxicological methods (01.11.2014)
Published in Journal of pharmacological and toxicological methods (01.11.2014)
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