Experimentally Increasing Titin Compliance in a Novel Mouse Model Attenuates the Frank-Starling Mechanism But Has a Beneficial Effect on Diastole
Methawasin, Mei, Hutchinson, Kirk R, Lee, Eun-Jeong, Smith, John E, Saripalli, Chandra, Hidalgo, Carlos G, Ottenheijm, Coen A.C, Granzier, Henk
Published in Circulation (New York, N.Y.) (13.05.2014)
Published in Circulation (New York, N.Y.) (13.05.2014)
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Journal Article
Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency
Ottenheijm, Coen A.C., Witt, Christian C., Stienen, Ger J., Labeit, Siegfried, Beggs, Alan H., Granzier, Henk
Published in Human molecular genetics (01.07.2009)
Published in Human molecular genetics (01.07.2009)
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Journal Article
Contractile Dysfunction of Left Ventricular Cardiomyocytes in Patients With Pulmonary Arterial Hypertension
Manders, Emmy, MSc, Bogaard, Harm-Jan, MD, PhD, Handoko, M. Louis, MD, PhD, van de Veerdonk, Marielle C., MD, Keogh, Anne, MD, Westerhof, Nico, PhD, Stienen, Ger J.M., PhD, dos Remedios, Cristobal G., PhD, Dsc, Humbert, Marc, MD, PhD, Dorfmüller, Peter, MD, PhD, Fadel, Elie, MD, PhD, Guignabert, Christophe, PhD, van der Velden, Jolanda, PhD, Vonk-Noordegraaf, Anton, MD, PhD, de Man, Frances S., PhD, Ottenheijm, Coen A.C., PhD
Published in Journal of the American College of Cardiology (08.07.2014)
Published in Journal of the American College of Cardiology (08.07.2014)
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Journal Article
Diaphragm Dysfunction in Chronic Obstructive Pulmonary Disease
Ottenheijm, Coen A. C, Heunks, Leo M. A, Sieck, Gary C, Zhan, Wen-Zhi, Jansen, Suzanne M, Degens, Hans, de Boo, Theo, Dekhuijzen, P. N. Richard
Published in American journal of respiratory and critical care medicine (15.07.2005)
Published in American journal of respiratory and critical care medicine (15.07.2005)
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Journal Article
Diaphragm Pathology in Critically Ill Patients With COVID-19 and Postmortem Findings From 3 Medical Centers
Shi, Zhonghua, de Vries, Heder J, Vlaar, Alexander P J, van der Hoeven, Johannes, Boon, Reinier A, Heunks, Leo M A, Ottenheijm, Coen A C
Published in JAMA internal medicine (01.01.2021)
Published in JAMA internal medicine (01.01.2021)
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Journal Article
Activation of the Ubiquitin-Proteasome Pathway in the Diaphragm in Chronic Obstructive Pulmonary Disease
Ottenheijm, Coen A. C, Heunks, Leo M. A, Li, Yi-Ping, Jin, Bingwen, Minnaard, Ronnie, van Hees, Hieronymus W. H, Dekhuijzen, P. N. Richard
Published in American journal of respiratory and critical care medicine (01.11.2006)
Published in American journal of respiratory and critical care medicine (01.11.2006)
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Journal Article
Right Ventricular Diastolic Impairment in Patients With Pulmonary Arterial Hypertension
Rain, Silvia, Handoko, M Louis, Trip, Pia, Gan, C Tji-Joong, Westerhof, Nico, Stienen, Ger J, Paulus, Walter J, Ottenheijm, Coen A.C, Marcus, J Tim, Dorfmüller, Peter, Guignabert, Christophe, Humbert, Marc, MacDonald, Peter, dos Remedios, Cris, Postmus, Piet E, Saripalli, Chandra, Hidalgo, Carlos G, Granzier, Henk L, Vonk-Noordegraaf, Anton, van der Velden, Jolanda, de Man, Frances S
Published in Circulation (New York, N.Y.) (29.10.2013)
Published in Circulation (New York, N.Y.) (29.10.2013)
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Journal Article
Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb
Laitila, Jenni M, McNamara, Elyshia L, Wingate, Catherine D, Goullee, Hayley, Ross, Jacob A, Taylor, Rhonda L, van der Pijl, Robbert, Griffiths, Lisa M, Harries, Rachel, Ravenscroft, Gianina, Clayton, Joshua S, Sewry, Caroline, Lawlor, Michael W, Ottenheijm, Coen A C, Bakker, Anthony J, Ochala, Julien, Laing, Nigel G, Wallgren-Pettersson, Carina, Pelin, Katarina, Nowak, Kristen J
Published in Acta neuropathologica communications (17.02.2020)
Published in Acta neuropathologica communications (17.02.2020)
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Journal Article
Titin and diaphragm dysfunction in mechanically ventilated rats
van Hees, Hieronymus W. H., Schellekens, Willem-Jan M., Andrade Acuña, Gilberto L., Linkels, Marianne, Hafmans, Theo, Ottenheijm, Coen A. C., Granzier, Henk L., Scheffer, Gert-Jan, van der Hoeven, Johannes G., Dekhuijzen, P. N. Richard, Heunks, Leo M. A.
Published in Intensive care medicine (01.04.2012)
Published in Intensive care medicine (01.04.2012)
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Journal Article
Positive End-Expiratory Pressure Ventilation Induces Longitudinal Atrophy in Diaphragm Fibers
Lindqvist, Johan, van den Berg, Marloes, van der Pijl, Robbert, Hooijman, Pleuni E, Beishuizen, Albertus, Elshof, Judith, de Waard, Monique, Girbes, Armand, Spoelstra-de Man, Angelique, Shi, Zhong-Hua, van den Brom, Charissa, Bogaards, Sylvia, Shen, Shengyi, Strom, Joshua, Granzier, Henk, Kole, Jeroen, Musters, René J P, Paul, Marinus A, Heunks, Leo M A, Ottenheijm, Coen A C
Published in American journal of respiratory and critical care medicine (15.08.2018)
Published in American journal of respiratory and critical care medicine (15.08.2018)
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Journal Article
Diaphragm muscle fiber weakness and ubiquitin-proteasome activation in critically ill patients
Hooijman, Pleuni E, Beishuizen, Albertus, Witt, Christian C, de Waard, Monique C, Girbes, Armand R J, Spoelstra-de Man, Angelique M E, Niessen, Hans W M, Manders, Emmy, van Hees, Hieronymus W H, van den Brom, Charissa E, Silderhuis, Vera, Lawlor, Michael W, Labeit, Siegfried, Stienen, Ger J M, Hartemink, Koen J, Paul, Marinus A, Heunks, Leo M A, Ottenheijm, Coen A C
Published in American journal of respiratory and critical care medicine (15.05.2015)
Published in American journal of respiratory and critical care medicine (15.05.2015)
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Journal Article
Positive end-expiratory pressure affects geometry and function of the human diaphragm
Jansen, Diana, Jonkman, Annemijn H., Vries, Heder J. de, Wennen, Myrte, Elshof, Judith, Hoofs, Maud A., van den Berg, Marloes, Man, Angélique M. E. de, Keijzer, Christiaan, Scheffer, Gert-Jan, van der Hoeven, Johannes G., Girbes, Armand, Tuinman, Pieter Roel, Marcus, J. Tim, Ottenheijm, Coen A. C., Heunks, Leo
Published in Journal of applied physiology (1985) (01.10.2021)
Published in Journal of applied physiology (1985) (01.10.2021)
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Journal Article
Diaphragm single-fiber weakness and loss of myosin in congestive heart failure rats
van Hees, Hieronymus W. H, van der Heijden, Henricus F. M, Ottenheijm, Coen A. C, Heunks, Leo M. A, Pigmans, Cindy J. C, Verheugt, Freek W. A, Brouwer, Rene M. H. J, Dekhuijzen, P. N. Richard
Published in American journal of physiology. Heart and circulatory physiology (01.07.2007)
Published in American journal of physiology. Heart and circulatory physiology (01.07.2007)
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Journal Article
Diaphragm adaptations in patients with COPD
Ottenheijm, Coen A C, Heunks, Leo M A, Dekhuijzen, Richard P N
Published in Respiratory research (24.01.2008)
Published in Respiratory research (24.01.2008)
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Journal Article
Skeletal myopathy in a rat model of postmenopausal heart failure with preserved ejection fraction
Kelley, Rachel C, Betancourt, Lauren, Noriega, Andrea M, Brinson, Suzanne C, Curbelo-Bermudez, Nuria, Hahn, Dongwoo, Kumar, Ravi A, Balazic, Eliza, Muscato, Derek R, Ryan, Terence E, van der Pijl, Robbert J, Shen, Shengyi, Ottenheijm, Coen A C, Ferreira, Leonardo F
Published in Journal of applied physiology (1985) (01.01.2022)
Published in Journal of applied physiology (1985) (01.01.2022)
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Journal Article
Titin N2A: More than a signaling node?
van der Pijl, Robbert J, Ottenheijm, Coen A C
Published in The Journal of general physiology (05.07.2021)
Published in The Journal of general physiology (05.07.2021)
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