Diatretol, an α, α'-dioxo-diketopiperazine, is a potent in vitro and in vivo antimalarial
Ishiyama, Aki, Hokari, Rei, Nonaka, Kenichi, Chiba, Takuya, Miura, Hiromi, Otoguro, Kazuhiko, Iwatsuki, Masato
Published in Journal of antibiotics (01.04.2021)
Published in Journal of antibiotics (01.04.2021)
Get full text
Journal Article
Isolation and Total Synthesis of Hoshinolactam, an Antitrypanosomal Lactam from a Marine Cyanobacterium
Ogawa, Hidetoshi, Iwasaki, Arihiro, Sumimoto, Shimpei, Iwatsuki, Masato, Ishiyama, Aki, Hokari, Rei, Otoguro, Kazuhiko, O̅mura, Satoshi, Suenaga, Kiyotake
Published in Organic letters (17.02.2017)
Published in Organic letters (17.02.2017)
Get full text
Journal Article
Actinoallolides A–E, New Anti-trypanosomal Macrolides, Produced by an Endophytic Actinomycete, Actinoallomurus fulvus MK10-036
Inahashi, Yuki, Iwatsuki, Masato, Ishiyama, Aki, Matsumoto, Atsuko, Hirose, Tomoyasu, Oshita, Jun, Sunazuka, Toshiaki, Panbangred, Watanalai, Takahashi, Yoko, Kaiser, Marcel, Otoguro, Kazuhiko, O̅mura, Satoshi
Published in Organic letters (20.02.2015)
Published in Organic letters (20.02.2015)
Get full text
Journal Article
Rapid and Systematic Exploration of Chemical Space Relevant to Artemisinins: Anti-malarial Activities of Skeletally Diversified Tetracyclic Peroxides and 6‑Aza-artemisinins
Bonepally, Karunakar Reddy, Takahashi, Norihito, Matsuoka, Naoya, Koi, Hikari, Mizoguchi, Haruki, Hiruma, Takahisa, Ochiai, Kyohei, Suzuki, Shun, Yamagishi, Yutaka, Oikawa, Hideaki, Ishiyama, Aki, Hokari, Rei, Iwatsuki, Masato, Otoguro, Kazuhiko, O̅mura, Satoshi, Kato, Nobutaka, Oguri, Hiroki
Published in Journal of organic chemistry (07.08.2020)
Published in Journal of organic chemistry (07.08.2020)
Get full text
Journal Article
Anti-trypanosomal compound, sagamilactam, a new polyene macrocyclic lactam from Actinomadura sp K13-0306
Kimura, Toru, Iwatsuki, Masato, Asami, Yukihiro, Ishiyama, Aki, Hokari, Rei, Otoguro, Kazuhiko, Matsumoto, Atsuko, Sato, Noriko, Shiomi, Kazuro, Takahashi, Yoko, Omura, Satoshi, Nakashima, Takuji
Published in Journal of antibiotics (01.11.2016)
Published in Journal of antibiotics (01.11.2016)
Get full text
Journal Article
Semisynthesis of Antitrypanosomal p-Quinone Analog Possesing the Komaroviquinone Pharmacophore
Aoyagi, Yutaka, Fujiwara, Koji, Takahashi, Yoshinao, Yano, Reiko, Hitotsuyanagi, Yukio, Takeya, Koichi, Aiyama, Ritsuo, Matsuzaki, Takeshi, Hashimoto, Shusuke, Nishihara-Tsukashima, Aki, Namatame, Miyuki, Ishiyama, Aki, Iwatsuki, Masato, Otoguro, Kazuhiko, Yamada, Haruki, Ōmura, Satoshi
Published in Chemical & pharmaceutical bulletin (01.04.2022)
Published in Chemical & pharmaceutical bulletin (01.04.2022)
Get full text
Journal Article
Mangromicins A and B: structure and antitrypanosomal activity of two new cyclopentadecane compounds from Lechevalieria aerocolonigenes K10-0216
Nakashima, Takuji, Iwatsuki, Masato, Ochiai, Junya, Kamiya, Yoshiyuki, Nagai, Kenichiro, Matsumoto, Atsuko, Ishiyama, Aki, Otoguro, Kazuhiko, Shiomi, Kazuro, Takahashi, Yōko, Ōmura, Satoshi
Published in Journal of antibiotics (01.03.2014)
Published in Journal of antibiotics (01.03.2014)
Get full text
Journal Article
Antimalarial troponoids, puberulic acid and viticolins; divergent synthesis and structure-activity relationship studies
Sennari, Goh, Saito, Ryo, Hirose, Tomoyasu, Iwatsuki, Masato, Ishiyama, Aki, Hokari, Rei, Otoguro, Kazuhiko, Ōmura, Satoshi, Sunazuka, Toshiaki
Published in Scientific reports (03.08.2017)
Published in Scientific reports (03.08.2017)
Get full text
Journal Article
In Vitro Antitrypanosomal Activity of the Secondary Metabolites from the Mutant Strain IU-3 of the Insect Pathogenic Fungus Ophiocordyceps coccidiicola NBRC 100683
Ganaha, Momoko, Yoshii, Kento, Ōtsuki, Yuuta, Iguchi, Miki, Okamoto, Yasuko, Iseki, Kanako, Ban, Sayaka, Ishiyama, Aki, Hokari, Rei, Iwatsuki, Masato, Otoguro, Kazuhiko, Ōmura, Satoshi, Hashimoto, Toshihiro, Noji, Masaaki, Umeyama, Akemi
Published in Chemical & pharmaceutical bulletin (2016)
Published in Chemical & pharmaceutical bulletin (2016)
Get full text
Journal Article
Borrelidin, a potent antimalarial: stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum
Ishiyama, Aki, Iwatsuki, Masato, Namatame, Miyuki, Nishihara-Tsukashima, Aki, Sunazuka, Toshiaki, Takahashi, Yoko, Ōmura, Satoshi, Otoguro, Kazuhiko
Published in Journal of antibiotics (01.05.2011)
Published in Journal of antibiotics (01.05.2011)
Get full text
Journal Article
Peyer's patch-immunomodulating glucans from sugar cane enhance protective immunity through stimulation of the hemopoietic system
Sakai, Yusuke, Sato, Masakazu, Funami, Yusuke, Ishiyama, Aki, Hokari, Rei, Iwatsuki, Masato, Nagai, Takayuki, Otoguro, Kazuhiko, Yamada, Haruki, Ōmura, Satoshi, Kiyohara, Hiroaki
Published in International journal of biological macromolecules (01.03.2019)
Published in International journal of biological macromolecules (01.03.2019)
Get full text
Journal Article
Asymmetric Total Synthesis of Indole Alkaloids Containing an Indoline Spiroaminal Framework
Yamada, Takeshi, Ideguchi-Matsushita, Tetsuya, Hirose, Tomoyasu, Shirahata, Tatsuya, Hokari, Rei, Ishiyama, Aki, Iwatsuki, Masato, Sugawara, Akihiro, Kobayashi, Yoshinori, Otoguro, Kazuhiko, Ōmura, Satoshi, Sunazuka, Toshiaki
Published in Chemistry : a European journal (10.08.2015)
Published in Chemistry : a European journal (10.08.2015)
Get full text
Journal Article
In vitro and in vivo antimalarial activity of puberulic acid and its new analogs, viticolins A-C, produced by Penicillium sp FKI-4410
Iwatsuki, Masato, Takada, Shohei, Mori, Mihoko, Ishiyama, Aki, Namatame, Miyuki, Nishihara-Tsukashima, Aki, Nonaka, Kenichi, Masuma, Rokuro, Otoguro, Kazuhiko, Shiomi, Kazuro, Omura, Satoshi
Published in Journal of antibiotics (01.02.2011)
Published in Journal of antibiotics (01.02.2011)
Get full text
Journal Article
Structure-Activity Relationship between Thiol Group-Trapping Ability of Morphinan Compounds with a Michael Acceptor and Anti- Plasmodium falciparum Activities
Kutsumura, Noriki, Koyama, Yasuaki, Saitoh, Tsuyoshi, Yamamoto, Naoshi, Nagumo, Yasuyuki, Miyata, Yoshiyuki, Hokari, Rei, Ishiyama, Aki, Iwatsuki, Masato, Otoguro, Kazuhiko, Ōmura, Satoshi, Nagase, Hiroshi
Published in Molecules (Basel, Switzerland) (02.03.2020)
Published in Molecules (Basel, Switzerland) (02.03.2020)
Get full text
Journal Article
In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei
Otoguro, Kazuhiko, Iwatsuki, Masato, Ishiyama, Aki, Namatame, Miyuki, Nishihara-Tukashima, Aki, Kiyohara, Hiroaki, Hashimoto, Toshihiro, Asakawa, Yoshinori, Ōmura, Satoshi, Yamada, Haruki
Published in Phytochemistry (Oxford) (01.11.2011)
Published in Phytochemistry (Oxford) (01.11.2011)
Get full text
Journal Article
New lycorine-type alkaloid from Lycoris traubii and evaluation of antitrypanosomal and antimalarial activities of lycorine derivatives
Toriizuka, Yosuke, Kinoshita, Eri, Kogure, Noriyuki, Kitajima, Mariko, Ishiyama, Aki, Otoguro, Kazuhiko, Yamada, Haruki, Ōmura, Satoshi, Takayama, Hiromitsu
Published in Bioorganic & medicinal chemistry (15.12.2008)
Published in Bioorganic & medicinal chemistry (15.12.2008)
Get full text
Journal Article
Promising lead compounds for novel antiprotozoals
Otoguro, Kazuhiko, Iwatsuki, Masato, Ishiyama, Aki, Namatame, Miyuki, Nishihara-Tukashima, Aki, Shibahara, Seiji, Kondo, Shinichi, Yamada, Haruki, Omura, Satoshi
Published in Journal of antibiotics (01.07.2010)
Published in Journal of antibiotics (01.07.2010)
Get full text
Journal Article
Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites
Otoguro, Kazuhiko, Ishiyama, Aki, Namatame, Miyuki, Nishihara, Aki, Furusawa, Toshiaki, Masuma, Rokuro, Shiomi, Kazuro, Takahashi, Yoko, Yamada, Haruki, Omura, Satoshi
Published in Journal of antibiotics (01.06.2008)
Published in Journal of antibiotics (01.06.2008)
Get full text
Journal Article
In vitro antitrypanosomal activity of the cyclodepsipeptides, cardinalisamides A-C, from the insect pathogenic fungus Cordyceps cardinalis NBRC 103832
Umeyama, Akemi, Takahashi, Koichi, Grudniewska, Aleksandra, Shimizu, Mina, Hayashi, Sayaka, Kato, Masayuki, Okamoto, Yasuko, Suenaga, Midori, Ban, Sayaka, Kumada, Toshio, Ishiyama, Aki, Iwatsuki, Masato, Otoguro, Kazuhiko, Omura, Satoshi, Hashimoto, Toshihiro
Published in Journal of antibiotics (01.02.2014)
Published in Journal of antibiotics (01.02.2014)
Get full text
Journal Article
In vitro and in vivo antitrypanosomal activities of three peptide antibiotics: leucinostatin A and B, alamethicin I and tsushimycin
Ishiyama, Aki, Otoguro, Kazuhiko, Iwatsuki, Masato, Iwatsuki, Masahito, Namatame, Miyuki, Nishihara, Aki, Nonaka, Kenichi, Kinoshita, Yuta, Takahashi, Yoko, Masuma, Rokuro, Shiomi, Kazuro, Yamada, Haruki, Omura, Satoshi
Published in Journal of antibiotics (01.06.2009)
Published in Journal of antibiotics (01.06.2009)
Get full text
Journal Article