Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
Schimmer, Aaron D., Welsh, Kate, Pinilla, Clemencia, Wang, Zhiliang, Krajewska, Maryla, Bonneau, Marie-Josee, Pedersen, Irene M., Kitada, Shinichi, Scott, Fiona L., Bailly-Maitre, Beatrice, Glinsky, Gennadi, Scudiero, Dominick, Sausville, Edward, Salvesen, Guy, Nefzi, Adel, Ostresh, John M., Houghten, Richard A., Reed, John C.
Published in Cancer cell (2004)
Published in Cancer cell (2004)
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Combinatorial Chemistry: Libraries from Libraries, the Art of the Diversity-Oriented Transformation of Resin-Bound Peptides and Chiral Polyamides to Low Molecular Weight Acyclic and Heterocyclic Compounds
Nefzi, Adel, Ostresh, John M, Yu, Jongping, Houghten, Richard A
Published in Journal of organic chemistry (28.05.2004)
Published in Journal of organic chemistry (28.05.2004)
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Mixture-Based Synthetic Combinatorial Libraries
Houghten, Richard A, Pinilla, Clemencia, Appel, Jon R, Blondelle, Sylvie E, Dooley, Colette T, Eichler, Jutta, Nefzi, Adel, Ostresh, John M
Published in Journal of medicinal chemistry (23.09.1999)
Published in Journal of medicinal chemistry (23.09.1999)
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Solid-Phase Synthesis of 1,5-Disubstituted 2-Aryliminoimidazolidines
Yu, Yongping, Ostresh, John M, Houghten, Richard A
Published in Journal of organic chemistry (03.05.2002)
Published in Journal of organic chemistry (03.05.2002)
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Solid-Phase Synthesis of Trisubstituted Bicyclic Guanidines via Cyclization of Reduced N-Acylated Dipeptides
Ostresh, John M, Schoner, Christa C, Hamashin, Vince T, Nefzi, Adel, Meyer, Jean-Philippe, Houghten, Richard A
Published in Journal of organic chemistry (27.11.1998)
Published in Journal of organic chemistry (27.11.1998)
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A Novel Approach for Solid-Phase Synthesis of Substituted Imidazolines and Bis-Imidazolines
Acharya, Achyuta N, Ostresh, John M, Houghten, Richard A
Published in Journal of organic chemistry (14.12.2001)
Published in Journal of organic chemistry (14.12.2001)
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Small molecule functional analogs of peptides that inhibit λ site-specific recombination and bind Holliday junctions
Ranjit, Dev K., Rideout, Marc C., Nefzi, Adel, Ostresh, John M., Pinilla, Clemencia, Segall, Anca M.
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Potent antimicrobial small molecules screened as inhibitors of tyrosine recombinases and Holliday junction-resolving enzymes
Rideout, Marc C., Boldt, Jeffrey L., Vahi-Ferguson, Gabriel, Salamon, Peter, Nefzi, Adel, Ostresh, John M., Giulianotti, Marc, Pinilla, Clemencia, Segall, Anca M.
Published in Molecular diversity (01.11.2011)
Published in Molecular diversity (01.11.2011)
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A Traceless Approach for the Parallel Solid-Phase Synthesis of 2-(Arylamino)quinazolinones
Yu, Yongping, Ostresh, John M, Houghten, Richard A
Published in Journal of organic chemistry (09.08.2002)
Published in Journal of organic chemistry (09.08.2002)
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Identification of potent and highly selective chiral tri-amine and tetra-amine μ opioid receptors ligands: An example of lead optimization using mixture-based libraries
Nefzi, Adel, Ostresh, John M., Appel, Jon R., Bidlack, Jean, Dooley, Colette T., Houghten, Richard A.
Published in Bioorganic & medicinal chemistry letters (15.08.2006)
Published in Bioorganic & medicinal chemistry letters (15.08.2006)
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"Libraries from Libraries": Chemical Transformation of Combinatorial Libraries to Extend the Range and Repertoire of Chemical Diversity
Ostresh, John M., Husar, Gregory M., Blondelle, Sylvie E., Dörner, Barbara, Weber, Patricia A., Houghten, Richard A.
Published in Proceedings of the National Academy of Sciences - PNAS (08.11.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (08.11.1994)
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