Functional Characterization of Mouse Organic Anion Transporting Peptide 1a4 in the Uptake and Efflux of Drugs Across the Blood-Brain Barrier
Ose, Atsushi, Kusuhara, Hiroyuki, Endo, Chihiro, Tohyama, Kimio, Miyajima, Mari, Kitamura, Satoshi, Sugiyama, Yuichi
Published in Drug metabolism and disposition (01.01.2010)
Published in Drug metabolism and disposition (01.01.2010)
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Journal Article
Quantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic Compounds
ENOKIZONO, Junichi, KUSUHARA, Hiroyuki, OSE, Atsushi, SCHINKEL, Alfred H, SUGIYAMA, Yuichi
Published in Drug metabolism and disposition (01.06.2008)
Published in Drug metabolism and disposition (01.06.2008)
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Journal Article
Limited Brain Distribution of [3R,4R,5S]-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate Phosphate (Ro 64-0802), a Pharmacologically Active Form of Oseltamivir, by Active Efflux across the Blood-Brain Barrier Mediated by Organic Anion Transporter 3 (Oat3/Slc22a8) and Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4)
OSE, Atsushi, ITO, Mototsugu, KUSUHARA, Hiroyuki, YAMATSUGU, Kenzo, KANAI, Motomu, SHIBASAKI, Masakatsu, HOSOKAWA, Masakiyo, SCHUETZ, John D, SUGIYAMA, Yuichi
Published in Drug metabolism and disposition (01.02.2009)
Published in Drug metabolism and disposition (01.02.2009)
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Journal Article
Pharmacokinetic Modeling and Monte Carlo Simulation to Predict Interindividual Variability in Human Exposure to Oseltamivir and Its Active Metabolite, Ro 64-0802
Ito, Mototsugu, Kusuhara, Hiroyuki, Ose, Atsushi, Kondo, Tsunenori, Tanabe, Kazunari, Nakayama, Hideki, Horita, Shigeru, Fujita, Takuya, Sugiyama, Yuichi
Published in The AAPS journal (01.01.2017)
Published in The AAPS journal (01.01.2017)
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Journal Article
P-glycoprotein Restricts the Penetration of Oseltamivir Across the Blood-Brain Barrier
OSE, Atsushi, KUSUHARA, Hiroyuki, YAMATSUGU, Kenzo, KANAI, Motomu, SHIBASAKI, Masakatsu, FUJITA, Takuya, YAMAMOTO, Akira, SUGIYAMA, Yuichi
Published in Drug metabolism and disposition (01.02.2008)
Published in Drug metabolism and disposition (01.02.2008)
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Journal Article
Diclofenac-Induced Inactivation of CYP3A4 and Its Stimulation by Quinidine
MASUBUCHI, Yasuhiro, OSE, Atsushi, HORIE, Toshiharu
Published in Drug metabolism and disposition (01.10.2002)
Published in Drug metabolism and disposition (01.10.2002)
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Journal Article
Population Pharmacokinetics, Exposure–Safety, and Probability of Target Attainment Analyses for Isavuconazole in Japanese Patients With Deep‐Seated Mycoses
Shirae, Shinichiro, Tsuruya, Yuri, Kozaki, Tomohito, Mizuhata, Junnosuke, Ose, Atsushi
Published in Journal of clinical pharmacology (01.06.2023)
Published in Journal of clinical pharmacology (01.06.2023)
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Journal Article
Mechanism-Based Inactivation of CYP2C11 by Diclofenac
MASUBUCHI, Yasuhiro, OSE, Atsushi, HORIE, Toshiharu
Published in Drug metabolism and disposition (01.09.2001)
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Published in Drug metabolism and disposition (01.09.2001)
Journal Article
Prediction of Fracture Risk From Early‐Stage Bone Markers in Patients With Osteoporosis Treated With Once‐Yearly Administered Zoledronic Acid
Kasai, Hidefumi, Mori, Yoko, Ose, Atsushi, Shiraki, Masataka, Tanigawara, Yusuke
Published in Journal of clinical pharmacology (01.05.2021)
Published in Journal of clinical pharmacology (01.05.2021)
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Journal Article
A Pharmacokinetic Bioequivalence Study Comparing Different‐Strength and ‐Size Capsules of Isavuconazonium Sulfate in Healthy Japanese Subjects
Shirae, Shinichiro, Mori, Yoko, Kozaki, Tomohito, Ose, Atsushi, Hasegawa, Setsuo
Published in Clinical pharmacology in drug development (01.09.2022)
Published in Clinical pharmacology in drug development (01.09.2022)
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Journal Article
Safety Profiles, Pharmacokinetics, and Changes in Bone Turnover Markers After Twice‐Weekly Subcutaneous Administration of Teriparatide in Healthy Japanese Postmenopausal Women: A Single‐Blind Randomized Study
Kumagai, Yuji, Ose, Atsushi, Tanaka, Kosuke, Sugimoto, Toshitsugu
Published in Clinical pharmacology in drug development (01.01.2020)
Published in Clinical pharmacology in drug development (01.01.2020)
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Journal Article
Relationship Between the Urinary Excretion Mechanisms of Drugs and Their Physicochemical Properties
Ito, Sumito, Ando, Hirotaka, Ose, Atsushi, Kitamura, Yoshiaki, Ando, Tomohiro, Kusuhara, Hiroyuki, Sugiyama, Yuichi
Published in Journal of pharmaceutical sciences (01.09.2013)
Published in Journal of pharmaceutical sciences (01.09.2013)
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Journal Article
Development of a Support Vector Machine-Based System to Predict Whether a Compound Is a Substrate of a Given Drug Transporter Using Its Chemical Structure
Ose, Atsushi, Toshimoto, Kota, Ikeda, Kazushi, Maeda, Kazuya, Yoshida, Shuya, Yamashita, Fumiyoshi, Hashida, Mitsuru, Ishida, Takashi, Akiyama, Yutaka, Sugiyama, Yuichi
Published in Journal of pharmaceutical sciences (01.07.2016)
Published in Journal of pharmaceutical sciences (01.07.2016)
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Journal Article
METHOD FOR PREVENTING OR TREATING OSTEOPOROSIS, CHARACTERIZED BY ADMINISTERING TERIPARATIDE OR SALT THEREOF AT A FREQUENCY OF TWICE A WEEK
TAKAO RYOKO, YAMAMOTO HIKARI, KITAGAWA KAZUHIKO, MAKIYAMA TAKASHI, OSE ATSUSHI, MINAMIDA TAKESHI, KATO AKIRA, KOIKE AKIRA, KITAMI AKIHIRO
Year of Publication 26.08.2021
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Year of Publication 26.08.2021
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