Towards personalized treatment for early stage HER2-positive breast cancer
Goutsouliak, Kristina, Veeraraghavan, Jamunarani, Sethunath, Vidyalakshmi, De Angelis, Carmine, Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel
Published in Nature reviews. Clinical oncology (01.04.2020)
Published in Nature reviews. Clinical oncology (01.04.2020)
Get full text
Journal Article
Targeting HER2 for the Treatment of Breast Cancer
Rimawi, Mothaffar F, Schiff, Rachel, Osborne, C. Kent
Published in Annual review of medicine (14.01.2015)
Published in Annual review of medicine (14.01.2015)
Get full text
Journal Article
Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer
Burstein, Matthew D, Tsimelzon, Anna, Poage, Graham M, Covington, Kyle R, Contreras, Alejandro, Fuqua, Suzanne A W, Savage, Michelle I, Osborne, C Kent, Hilsenbeck, Susan G, Chang, Jenny C, Mills, Gordon B, Lau, Ching C, Brown, Powel H
Published in Clinical cancer research (01.04.2015)
Published in Clinical cancer research (01.04.2015)
Get full text
Journal Article
Metastasis dormancy in estrogen receptor-positive breast cancer
Zhang, Xiang H-F, Giuliano, Mario, Trivedi, Meghana V, Schiff, Rachel, Osborne, C Kent
Published in Clinical cancer research (01.12.2013)
Published in Clinical cancer research (01.12.2013)
Get full text
Journal Article
The Osteogenic Niche Promotes Early-Stage Bone Colonization of Disseminated Breast Cancer Cells
Wang, Hai, Yu, Cuijuan, Gao, Xia, Welte, Thomas, Muscarella, Aaron M., Tian, Lin, Zhao, Hong, Zhao, Zhen, Du, Shiyu, Tao, Jianning, Lee, Brendan, Westbrook, Thomas F., Wong, Stephen T.C., Jin, Xin, Rosen, Jeffrey M., Osborne, C. Kent, Zhang, Xiang H.-F.
Published in Cancer cell (09.02.2015)
Published in Cancer cell (09.02.2015)
Get full text
Journal Article
Crosstalk between the Estrogen Receptor and the HER Tyrosine Kinase Receptor Family: Molecular Mechanism and Clinical Implications for Endocrine Therapy Resistance
Arpino, Grazia, Wiechmann, Lisa, Osborne, C. Kent, Schiff, Rachel
Published in Endocrine reviews (01.04.2008)
Published in Endocrine reviews (01.04.2008)
Get full text
Journal Article
Multicenter Phase II Study of Neoadjuvant Lapatinib and Trastuzumab With Hormonal Therapy and Without Chemotherapy in Patients With Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer: TBCRC 006
RIMAWI, Mothaffar F, MAYER, Ingrid A, SCHIFF, Rachel, KENT OSBORNE, C, CHANG, Jenny C, FORERO, Andres, NANDA, Rita, GOETZ, Matthew P, RODRIGUEZ, Angel A, PAVLICK, Anne C, TAO WANG, HILSENBECK, Susan G, GUTIERREZ, Carolina
Published in Journal of clinical oncology (10.05.2013)
Published in Journal of clinical oncology (10.05.2013)
Get full text
Journal Article
Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor-Positive Early Breast Cancer: PALLET Trial
Johnston, Stephen, Puhalla, Shannon, Wheatley, Duncan, Ring, Alistair, Barry, Peter, Holcombe, Chris, Boileau, Jean Francois, Provencher, Louise, Robidoux, André, Rimawi, Mothaffar, McIntosh, Stuart A, Shalaby, Ibrahim, Stein, Robert C, Thirlwell, Michael, Dolling, David, Morden, James, Snowdon, Claire, Perry, Sophie, Cornman, Chester, Batten, Leona M, Jeffs, Lisa K, Dodson, Andrew, Martins, Vera, Modi, Arjun, Osborne, C Kent, Pogue-Geile, Katherine L, Cheang, Maggie Chon U, Wolmark, Norman, Julian, Thomas B, Fisher, Kate, MacKenzie, Mairead, Wilcox, Maggie, Huang Bartlett, Cynthia, Koehler, Maria, Dowsett, Mitch, Bliss, Judith M, Jacobs, Samuel A
Published in Journal of clinical oncology (20.01.2019)
Published in Journal of clinical oncology (20.01.2019)
Get full text
Journal Article
Low PTEN levels and PIK3CA mutations predict resistance to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2 over-expressing breast cancer
Rimawi, Mothaffar F., De Angelis, Carmine, Contreras, Alejandro, Pareja, Fresia, Geyer, Felipe C., Burke, Kathleen A., Herrera, Sabrina, Wang, Tao, Mayer, Ingrid A., Forero, Andres, Nanda, Rita, Goetz, Matthew P., Chang, Jenny C., Krop, Ian E., Wolff, Antonio C., Pavlick, Anne C., Fuqua, Suzanne A. W., Gutierrez, Carolina, Hilsenbeck, Susan G., Li, Marilyn M., Weigelt, Britta, Reis-Filho, Jorge S., Kent Osborne, C., Schiff, Rachel
Published in Breast cancer research and treatment (01.02.2018)
Published in Breast cancer research and treatment (01.02.2018)
Get full text
Journal Article
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer
Fu, Xiaoyong, Pereira, Resel, De Angelis, Carmine, Veeraraghavan, Jamunarani, Nanda, Sarmistha, Qin, Lanfang, Cataldo, Maria L., Sethunath, Vidyalakshmi, Mehravaran, Sepideh, Gutierrez, Carolina, Chamness, Gary C., Feng, Qin, O’Malley, Bert W., Selenica, Pier, Weigelt, Britta, Reis-Filho, Jorge S., Cohen, Ofir, Wagle, Nikhil, Nardone, Agostina, Jeselsohn, Rinath, Brown, Myles, Rimawi, Mothaffar F., Osborne, C. Kent, Schiff, Rachel
Published in Proceedings of the National Academy of Sciences - PNAS (26.12.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (26.12.2019)
Get full text
Journal Article
An epigenomic approach to therapy for tamoxifen-resistant breast cancer
Feng, Qin, Zhang, Zheng, Shea, Martin J, Creighton, Chad J, Coarfa, Cristian, Hilsenbeck, Susan G, Lanz, Rainer, He, Bin, Wang, Lei, Fu, Xiaoyong, Nardone, Agostina, Song, Yongcheng, Bradner, James, Mitsiades, Nicholas, Mitsiades, Constantine S, Osborne, C Kent, Schiff, Rachel, O'Malley, Bert W
Published in Cell research (01.07.2014)
Published in Cell research (01.07.2014)
Get full text
Journal Article
Loss of Phosphatase and Tensin Homolog or Phosphoinositol-3 Kinase Activation and Response to Trastuzumab or Lapatinib in Human Epidermal Growth Factor Receptor 2–Overexpressing Locally Advanced Breast Cancers
DAVE, Bhuvanesh, MIGLIACCIO, Ilenia, RIMAWI, Mothaffar, SCHIFF, Rachel, ARTEAGA, Carlos, KENT OSBORNE, C, CHANG, Jenny C, GUTIERREZ, M. Carolina, WU, Meng-Fen, CHAMNESS, Gary C, WONG, Helen, NARASANNA, Archana, CHAKRABARTY, Anindita, HILSENBECK, Susan G, JIAN HUANG
Published in Journal of clinical oncology (10.01.2011)
Published in Journal of clinical oncology (10.01.2011)
Get full text
Journal Article
The changing role of ER in endocrine resistance
Nardone, Agostina, De Angelis, Carmine, Trivedi, Meghana V, Osborne, C. Kent, Schiff, Rachel
Published in Breast (Edinburgh) (01.11.2015)
Published in Breast (Edinburgh) (01.11.2015)
Get full text
Journal Article
Estrogen Receptor Status by Immunohistochemistry Is Superior to the Ligand-Binding Assay for Predicting Response to Adjuvant Endocrine Therapy in Breast Cancer
Harvey, Jennet M, Clark, Gary M, Osborne, C Kent, Allred, D Craig
Published in Journal of clinical oncology (01.03.2023)
Published in Journal of clinical oncology (01.03.2023)
Get full text
Journal Article
Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy
Li, Xiaoxian, Lewis, Michael T., Huang, Jian, Gutierrez, Carolina, Osborne, C. Kent, Wu, Meng-Fen, Hilsenbeck, Susan G., Pavlick, Anne, Zhang, Xiaomei, Chamness, Gary C., Wong, Helen, Rosen, Jeffrey, Chang, Jenny C.
Published in JNCI : Journal of the National Cancer Institute (07.05.2008)
Published in JNCI : Journal of the National Cancer Institute (07.05.2008)
Get full text
Journal Article
TBCRC023: A Randomized Phase II Neoadjuvant Trial of Lapatinib Plus Trastuzumab Without Chemotherapy for 12 versus 24 Weeks in Patients with HER2-Positive Breast Cancer
Rimawi, Mothaffar F, Niravath, Polly, Wang, Tao, Rexer, Brent N, Forero, Andres, Wolff, Antonio C, Nanda, Rita, Storniolo, Anna M, Krop, Ian, Goetz, Matthew P, Nangia, Julie R, Jiralerspong, Sao, Pavlick, Anne, Veeraraghavan, Jamunarani, De Angelis, Carmine, Gutierrez, Carolina, Schiff, Rachel, Hilsenbeck, Susan G, Osborne, C Kent
Published in Clinical cancer research (15.02.2020)
Published in Clinical cancer research (15.02.2020)
Get full text
Journal Article