Pharmacokinetic Data Are Predictive of In Vivo Efficacy for Cefixime and Ceftriaxone against Susceptible and Resistant Neisseria gonorrhoeae Strains in the Gonorrhea Mouse Model
Connolly, Kristie L, Eakin, Ann E, Gomez, Carolina, Osborn, Blaire L, Unemo, Magnus, Jerse, Ann E
Published in Antimicrobial agents and chemotherapy (01.03.2019)
Published in Antimicrobial agents and chemotherapy (01.03.2019)
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FDA Approval Summary: Pembrolizumab, Atezolizumab, and Cemiplimab-rwlc as Single Agents for First-Line Treatment of Advanced/Metastatic PD-L1-High NSCLC
Akinboro, Oladimeji, Larkins, Erin, Pai-Scherf, Lee H, Mathieu, Luckson N, Ren, Yi, Cheng, Joyce, Fiero, Mallorie H, Fu, Wentao, Bi, Youwei, Kalavar, Shyam, Jafri, Samina, Mishra-Kalyani, Pallavi S, Fourie Zirkelbach, Jeanne, Li, Hongshan, Zhao, Hong, He, Kun, Helms, Whitney S, Chuk, Meredith K, Wang, Min, Bulatao, Ilynn, Herz, Jonathan, Osborn, Blaire L, Xu, Yuan, Liu, Jiang, Gong, Yutao, Sickafuse, Sharon, Cohen, Rebecca, Donoghue, Martha, Pazdur, Richard, Beaver, Julia A, Singh, Harpreet
Published in Clinical cancer research (01.06.2022)
Published in Clinical cancer research (01.06.2022)
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Thorough QT Study To Evaluate the Effect of Zoliflodacin, a Novel Therapeutic for Gonorrhea, on Cardiac Repolarization in Healthy Adults
Newman, Lori M, Kankam, Martin, Nakamura, Aya, Conrad, Tom, Mueller, John, O'Donnell, John, Osborn, Blaire L, Gu, Kenan, Saviolakis, George A
Published in Antimicrobial agents and chemotherapy (17.11.2021)
Published in Antimicrobial agents and chemotherapy (17.11.2021)
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A Pharmacoepidemiologic Study of the Safety and Effectiveness of Clindamycin in Infants
Greenberg, Rachel G, Wu, Huali, Maharaj, Anil, Cohen-Wolkowiez, Michael, Tomashek, Kay M, Osborn, Blaire L, Clark, Reese H, Walter, Emmanuel B
Published in The Pediatric infectious disease journal (01.03.2020)
Published in The Pediatric infectious disease journal (01.03.2020)
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In Vivo Activity of Amodiaquine against Ebola Virus Infection
DeWald, Lisa Evans, Johnson, Joshua C., Gerhardt, Dawn M., Torzewski, Lisa M., Postnikova, Elena, Honko, Anna N., Janosko, Krisztina, Huzella, Louis, Dowling, William E., Eakin, Ann E., Osborn, Blaire L., Gahagen, Janet, Tang, Liang, Green, Carol E., Mirsalis, Jon C., Holbrook, Michael R., Jahrling, Peter B., Dyall, Julie, Hensley, Lisa E.
Published in Scientific reports (27.12.2019)
Published in Scientific reports (27.12.2019)
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A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients
Bain, Vincent G., Kaita, Kelly D., Yoshida, Eric M., Swain, Mark G., Heathcote, E. Jenny, Neumann, Avidan U., Fiscella, Michele, Yu, Ren, Osborn, Blaire L., Cronin, Patrick W., Freimuth, William W., McHutchison, John G., Subramanian, G. Mani
Published in Journal of hepatology (01.04.2006)
Published in Journal of hepatology (01.04.2006)
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Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferon-alpha fusion protein in cynomolgus monkeys
Osborn, Blaire L, Olsen, Henrik S, Nardelli, Bernardetta, Murray, James H, Zhou, Joe X H, Garcia, Andrew, Moody, Gordon, Zaritskaya, Liubov S, Sung, Cynthia
Published in The Journal of pharmacology and experimental therapeutics (01.11.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2002)
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Pharmacokinetics and in vitro and in vivo anti-tumor response of an interleukin-2-human serum albumin fusion protein in mice
MELDER, Robert J, OSBORN, Blaire L, GRZEGORZEWSKI, Krzysztof J, GALLANT, Gilles, RICCOBENE, Todd, KANAKARAJ, Palanisamy, PING WEI, GUOXIAN CHEN, STOLOW, David, HALPERN, Wendy Green, MIGONE, Thi-Sau, QI WANG
Published in Cancer Immunology, Immunotherapy (01.06.2005)
Published in Cancer Immunology, Immunotherapy (01.06.2005)
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A Phase 1 Study of PAmAb, a Fully Human Monoclonal Antibody against Bacillus anthracis Protective Antigen, in Healthy Volunteers
Subramanian, G. Mani, Cronin, Patrick W., Poley, Gerald, Weinstein, Andrea, Stoughton, Susan M., Zhong, John, Ou, Ying, Zmuda, Jonathan F., Osborn, Blaire L., Freimuth, William W.
Published in Clinical infectious diseases (01.07.2005)
Published in Clinical infectious diseases (01.07.2005)
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Albutropin: a growth hormone–albumin fusion with improved pharmacokinetics and pharmacodynamics in rats and monkeys
Osborn, Blaire L, Sekut, Les, Corcoran, Marta, Poortman, Carol, Sturm, Bonnie, Chen, Guoxian, Mather, Donald, Lin, Hsiu Ling, Parry, Tom J
Published in European journal of pharmacology (05.12.2002)
Published in European journal of pharmacology (05.12.2002)
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A Phase I/II study evaluating escalating doses of recombinant human albumin-interferon-alpha fusion protein in chronic hepatitis C patients who have failed previous interferon-alpha-based therapy
Balan, Vijayan, Nelson, David R, Sulkowski, Mark S, Everson, Gregory T, Lambiase, Louis R, Wiesner, Rusell H, Dickson, Rolland C, Post, Anthony B, Redfield, Robert R, Davis, Gary L, Neumann, Avidan U, Osborn, Blaire L, Freimuth, William W, Subramanian, G Mani
Published in Antiviral therapy (2006)
Published in Antiviral therapy (2006)
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Development of a Long-Acting Insulin Analog Using Albumin Fusion Technology
DUTTAROY, Alokesh, KANAKARAJ, Palanisamy, CROSSAN, Dan, BOCK, Jason, KAUFMAN, Thomas E, REAVEY, Peter, CAREY-BARBER, Melisa, KRISHNAN, Surekha R, GARCIA, Andy, MURPHY, Kelly, SISKIND, Jana K, MCLEAN, Malia A, OSBORN, Blaire L, CHENG, Susan, RUBEN, Steve, BIRSE, Charles E, BLONDEL, Olivier, SCHNEIDER, Helmut, PICKERAL, Oxana K, CHEN, Cecil, GUIYI ZHANG, KAITHAMANA, Shashi, SINGH, Mallika, SCHULINGKAMP, Robert
Published in Diabetes (New York, N.Y.) (01.01.2005)
Published in Diabetes (New York, N.Y.) (01.01.2005)
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New and modified interferon alfas: preclinical and clinical data
Masci, Paul, Bukowski, Ronald M, Patten, Phillip A, Osborn, Blaire L, Borden, Ernest C
Published in Current oncology reports (01.03.2003)
Published in Current oncology reports (01.03.2003)
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Differential toxicity of camptothecin, topotecan and 9-aminocamptothecin to human, canine, and murine myeloid progenitors (CFU-GM) in vitro
ERICKSON-MILLER, C. L, MAY, R. D, TOMASZEWSKI, J, OSBORN, B, MURPHY, M. J, PAGE, J. G, PARCHMENT, R. E
Published in Cancer chemotherapy and pharmacology (1997)
Published in Cancer chemotherapy and pharmacology (1997)
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Phase Ib Trial To Evaluate the Safety and Pharmacokinetics of Multiple Ascending Doses of Filociclovir (MBX-400, Cyclopropavir) in Healthy Volunteers
Rouphael, Nadine G, Hurwitz, Selwyn J, Hart, Mari, Beck, Allison, Anderson, Evan J, Deye, Gregory, Osborn, Blaire, Cai, Shu Yi, Focht, Chris, Amegashie, Cyrille, Bowlin, Terry L, Brooks, Jennifer, Mulligan, Mark J
Published in Antimicrobial agents and chemotherapy (01.09.2019)
Published in Antimicrobial agents and chemotherapy (01.09.2019)
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Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiota
Lomeli, Barbara K, Galbraith, Hal, Schettler, Jared, Saviolakis, George A, El-Amin, Wael, Osborn, Blaire, Ravel, Jacques, Hazleton, Keith, Lozupone, Catherine A, Evans, Ronald J, Bell, Stacie J, Ochsner, Urs A, Jarvis, Thale C, Baqar, Shahida, Janjic, Nebojsa
Published in Antimicrobial agents and chemotherapy (20.12.2019)
Published in Antimicrobial agents and chemotherapy (20.12.2019)
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Isotopic Differences in Human Growth Hormone Preparations
Abramson, Fred P, Osborn, Blaire L, Teffera, Yohannes
Published in Analytical chemistry (Washington) (01.06.1996)
Published in Analytical chemistry (Washington) (01.06.1996)
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Population Pharmacokinetics of Moxifloxacin in Children
Greenberg, Rachel G., Landersdorfer, Cornelia B., Rivera-Chaparro, Nazario, Harward, Melissa, Conrad, Thomas, Nakamura, Aya, Kirkpatrick, Carl M., Gu, Kenan, Ghazaryhan, Varduhi, Osborn, Blaire, Walter, Emmanuel B.
Published in Paediatric drugs (01.03.2022)
Published in Paediatric drugs (01.03.2022)
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Phase 1 Study of the Effects of the Tuberculosis Treatment Pretomanid, Alone and in Combination With Moxifloxacin, on the QTc Interval in Healthy Volunteers
Li, Mengchun, Saviolakis, George A., El‐Amin, Wael, Makhene, Mamodikoe K., Osborn, Blaire, Nedelman, Jerry, Yang, Tian J., Everitt, Daniel
Published in Clinical pharmacology in drug development (01.06.2021)
Published in Clinical pharmacology in drug development (01.06.2021)
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Examining the origin of melatonin from a "natural" source by isotope ratio mass spectrometry with liquid chromatographic introduction
Chen, P. (George Washington University, Washington, DC.), Osborn, B.L, Abramson, F.P
Published in Journal of AOAC International (01.01.1998)
Published in Journal of AOAC International (01.01.1998)
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