Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
Akira, Shizuo, Hemmi, Hiroaki, Kaisho, Tsuneyasu, Takeuchi, Osamu, Sato, Shintaro, Sanjo, Hideki, Hoshino, Katsuaki, Horiuchi, Takao, Tomizawa, Hideyuki, Takeda, Kiyoshi
Published in Nature immunology (01.02.2002)
Published in Nature immunology (01.02.2002)
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Cyclin J-CDK complexes limit innate immune responses by reducing proinflammatory changes in macrophage metabolism
Chong, Yee Kien, Tartey, Sarang, Yoshikawa, Yuki, Imami, Koshi, Li, Songling, Yoshinaga, Masanori, Hirabayashi, Ai, Liu, Guohao, Vandenbon, Alexis, Hia, Fabian, Uehata, Takuya, Mino, Takashi, Suzuki, Yutaka, Noda, Takeshi, Ferrandon, Dominique, Standley, Daron M, Ishihama, Yasushi, Takeuchi, Osamu
Published in Science signaling (12.04.2022)
Published in Science signaling (12.04.2022)
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Nanoparticle‐Mediated Delivery of Mitochondrial Division Inhibitor 1 to the Myocardium Protects the Heart From Ischemia‐Reperfusion Injury Through Inhibition of Mitochondria Outer Membrane Permeabilization: A New Therapeutic Modality for Acute Myocardial Infarction
Ishikita, Ayako, Matoba, Tetsuya, Ikeda, Gentaro, Koga, Jun‐ichiro, Mao, Yajing, Nakano, Kaku, Takeuchi, Osamu, Sadoshima, Junichi, Egashira, Kensuke
Published in Journal of the American Heart Association (22.07.2016)
Published in Journal of the American Heart Association (22.07.2016)
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Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity
Schulz, Oliver, Pichlmair, Andreas, Rehwinkel, Jan, Rogers, Neil C, Scheuner, Donalyn, Kato, Hiroki, Takeuchi, Osamu, Akira, Shizuo, Kaufman, Randal J, Reis e Sousa, Caetano
Published in Cell host & microbe (20.05.2010)
Published in Cell host & microbe (20.05.2010)
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Functional dissection of the KRAS G12C mutation by comparison among multiple oncogenic driver mutations in a lung cancer cell line model
Kobayashi, Keigo, Terai, Hideki, Yasuda, Hiroyuki, Hamamoto, Junko, Hayashi, Yuichiro, Takeuchi, Osamu, Mitsuishi, Yoichiro, Masuzawa, Keita, Manabe, Tadashi, Ikemura, Shinnosuke, Kawada, Ichiro, Suzuki, Yukio, Soejima, Kenzo, Fukunaga, Koichi
Published in Biochemical and biophysical research communications (01.01.2021)
Published in Biochemical and biophysical research communications (01.01.2021)
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p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis
Kirsch, David G, Santiago, Philip M, di Tomaso, Emmanuelle, Sullivan, Julie M, Hou, Wu-Shiun, Dayton, Talya, Jeffords, Laura B, Sodha, Pooja, Mercer, Kim L, Cohen, Rhianna, Takeuchi, Osamu, Korsmeyer, Stanley J, Bronson, Roderick T, Kim, Carla F, Haigis, Kevin M, Jain, Rakesh K, Jacks, Tyler
Published in Science (American Association for the Advancement of Science) (29.01.2010)
Published in Science (American Association for the Advancement of Science) (29.01.2010)
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Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
Coban, Cevayir, Ishii, Ken J, Kawai, Taro, Hemmi, Hiroaki, Sato, Shintaro, Uematsu, Satoshi, Yamamoto, Masahiro, Takeuchi, Osamu, Itagaki, Sawako, Kumar, Nirbhay, Horii, Toshihiro, Akira, Shizuo
Published in The Journal of experimental medicine (03.01.2005)
Published in The Journal of experimental medicine (03.01.2005)
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Cutting Edge: Role of Toll-Like Receptor 1 in Mediating Immune Response to Microbial Lipoproteins
Takeuchi, Osamu, Sato, Shintaro, Horiuchi, Takao, Hoshino, Katsuaki, Takeda, Kiyoshi, Dong, Zhongyun, Modlin, Robert L, Akira, Shizuo
Published in The Journal of immunology (1950) (01.07.2002)
Published in The Journal of immunology (1950) (01.07.2002)
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Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions
Yokogawa, Mariko, Tsushima, Takashi, Noda, Nobuo N., Kumeta, Hiroyuki, Enokizono, Yoshiaki, Yamashita, Kazuo, Standley, Daron M., Takeuchi, Osamu, Akira, Shizuo, Inagaki, Fuyuhiko
Published in Scientific reports (01.03.2016)
Published in Scientific reports (01.03.2016)
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The Transcription Factor Jdp2 Controls Bone Homeostasis and Antibacterial Immunity by Regulating Osteoclast and Neutrophil Differentiation
Maruyama, Kenta, Fukasaka, Masahiro, Vandenbon, Alexis, Saitoh, Tatsuya, Kawasaki, Takumi, Kondo, Takeshi, Yokoyama, Kazunari K., Kidoya, Hiroyasu, Takakura, Nobuyuki, Standley, Daron, Takeuchi, Osamu, Akira, Shizuo
Published in Immunity (Cambridge, Mass.) (14.12.2012)
Published in Immunity (Cambridge, Mass.) (14.12.2012)
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Lymphocytoid Choriomeningitis Virus Activates Plasmacytoid Dendritic Cells and Induces a Cytotoxic T-Cell Response via MyD88
JUNG, Andreas, KATO, Hiroki, KUMAGAI, Yutaro, KUMAR, Himanshu, KAWAI, Taro, TAKEUCHI, Osamu, AKIRA, Shizuo
Published in Journal of Virology (01.01.2008)
Published in Journal of Virology (01.01.2008)
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Hyperfructosemia in sleep disordered breathing: metabolome analysis of Nagahama study
Nakatsuka, Yoshinari, Murase, Kimihiko, Sonomura, Kazuhiro, Tabara, Yasuharu, Nagasaki, Tadao, Hamada, Satoshi, Matsumoto, Takeshi, Minami, Takuma, Kanai, Osamu, Takeyama, Hirofumi, Sunadome, Hironobu, Takahashi, Naomi, Nakamoto, Isuzu, Tanizawa, Kiminobu, Handa, Tomohiro, Sato, Taka-Aki, Komenami, Naoko, Wakamura, Tomoko, Morita, Satoshi, Takeuchi, Osamu, Nakayama, Takeo, Hirai, Toyohiro, Kamatani, Yoichiro, Matsuda, Fumihiko, Chin, Kazuo
Published in Scientific reports (05.08.2023)
Published in Scientific reports (05.08.2023)
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Phase-controllable multi-laser system with coaxially combined near-infrared and subcycle mid-infrared and THz pulsed beams
Arashida, Yusuke, Umeda, Naoki, Mogi, Hiroyuki, Ishikawa, Masashi, Hatanaka, Akira, Takeuchi, Osamu, Yoshida, Shoji, Shigekawa, Hidemi
Published in Applied physics express (01.09.2022)
Published in Applied physics express (01.09.2022)
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A Lipopolysaccharide from Pantoea Agglomerans Is a Promising Adjuvant for Sublingual Vaccines to Induce Systemic and Mucosal Immune Responses in Mice via TLR4 Pathway
Fukasaka, Masahiro, Asari, Daisuke, Kiyotoh, Eiji, Okazaki, Arimichi, Gomi, Yasuyuki, Tanimoto, Takeshi, Takeuchi, Osamu, Akira, Shizuo, Hori, Mitsuhiko
Published in PloS one (15.05.2015)
Published in PloS one (15.05.2015)
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Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
Akira, Shizuo, Yamamoto, Masahiro, Okamoto, Toru, Takeda, Kiyoshi, Sato, Shintaro, Sanjo, Hideki, Uematsu, Satoshi, Saitoh, Tatsuya, Yamamoto, Naoki, Sakurai, Hiroaki, Ishii, Ken J, Yamaoka, Shoji, Kawai, Taro, Matsuura, Yoshiharu, Takeuchi, Osamu
Published in Nature Immunology (01.09.2006)
Published in Nature Immunology (01.09.2006)
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Ultrafast nanoscale exciton dynamics via laser-combined scanning tunneling microscopy in atomically thin materials
Mogi, Hiroyuki, Arashida, Yusuke, Kikuchi, Ryusei, Mizuno, Ryosuke, Wakabayashi, Jun, Wada, Naoki, Miyata, Yasumitsu, Taninaka, Atsushi, Yoshida, Shoji, Takeuchi, Osamu, Shigekawa, Hidemi
Published in NPJ 2D materials and applications (14.10.2022)
Published in NPJ 2D materials and applications (14.10.2022)
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Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy
Taninaka, Atsushi, Kurokawa, Hiromi, Kamiyanagi, Mayuka, Ochiai, Takahiro, Arashida, Yusuke, Takeuchi, Osamu, Matsui, Hirofumi, Shigekawa, Hidemi
Published in Communications biology (28.11.2023)
Published in Communications biology (28.11.2023)
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Lipopolysaccharide Stimulates the MyD88-Independent Pathway and Results in Activation of IFN-Regulatory Factor 3 and the Expression of a Subset of Lipopolysaccharide-Inducible Genes
Kawai, Taro, Takeuchi, Osamu, Fujita, Takashi, Inoue, Jun-ichiro, Muhlradt, Peter F, Sato, Shintaro, Hoshino, Katsuaki, Akira, Shizuo
Published in The Journal of immunology (1950) (15.11.2001)
Published in The Journal of immunology (1950) (15.11.2001)
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