Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity
Lytrivi, Maria, Ghaddar, Kassem, Lopes, Miguel, Rosengren, Victoria, Piron, Anthony, Yi, Xiaoyan, Johansson, Henrik, Lehtiö, Janne, Igoillo-Esteve, Mariana, Cunha, Daniel A, Marselli, Lorella, Marchetti, Piero, Ortsäter, Henrik, Eizirik, Decio L, Cnop, Miriam
Published in BMC genomics (26.08.2020)
Published in BMC genomics (26.08.2020)
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Journal Article
Penile cavernous sinusoids are Prox1-positive hybrid vessels
Schnabellehner, Sarah, Kraft, Marle, Schoofs, Hans, Ortsäter, Henrik, Mäkinen, Taija
Published in Vascular biology (01.01.2024)
Published in Vascular biology (01.01.2024)
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Journal Article
Protein phosphatases in pancreatic islets
Ortsäter, Henrik, Grankvist, Nina, Honkanen, Richard E, Sjöholm, Åke
Published in Journal of endocrinology (01.06.2014)
Published in Journal of endocrinology (01.06.2014)
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Journal Article
Diazoxide-induced β-cell rest reduces endoplasmic reticulum stress in lipotoxic β-cells
Sargsyan, Ernest, Ortsäter, Henrik, Thorn, Kristofer, Bergsten, Peter
Published in Journal of endocrinology (01.10.2008)
Published in Journal of endocrinology (01.10.2008)
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Journal Article
Disruption of Serine/Threonine Protein Phosphatase 5 (PP5:PPP5c) in Mice Reveals a Novel Role for PP5 in the Regulation of Ultraviolet Light-induced Phosphorylation of Serine/Threonine Protein Kinase Chk1 (CHEK1)
Amable, Lauren, Grankvist, Nina, Largen, Jason W., Ortsäter, Henrik, Sjöholm, Åke, Honkanen, Richard E.
Published in The Journal of biological chemistry (25.11.2011)
Published in The Journal of biological chemistry (25.11.2011)
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Journal Article
Liraglutide counteracts obesity and glucose intolerance in a mouse model of glucocorticoid-induced metabolic syndrome
Fransson, Liselotte, Dos Santos, Cristiane, Wolbert, Petra, Sjöholm, Ake, Rafacho, Alex, Ortsäter, Henrik
Published in Diabetology and metabolic syndrome (14.01.2014)
Published in Diabetology and metabolic syndrome (14.01.2014)
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Journal Article
Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation
Martinez-Corral, Ines, Zhang, Yan, Petkova, Milena, Ortsäter, Henrik, Sjöberg, Sofie, Castillo, Sandra D., Brouillard, Pascal, Libbrecht, Louis, Saur, Dieter, Graupera, Mariona, Alitalo, Kari, Boon, Laurence, Vikkula, Miikka, Mäkinen, Taija
Published in Nature communications (08.06.2020)
Published in Nature communications (08.06.2020)
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Journal Article
The DPP-4 Inhibitor Linagliptin Counteracts Stroke in the Normal and Diabetic Mouse Brain
Darsalia, Vladimer, Ortsäter, Henrik, Olverling, Anna, Darlöf, Emilia, Wolbert, Petra, Nyström, Thomas, Klein, Thomas, Sjöholm, Åke, Patrone, Cesare
Published in Diabetes (New York, N.Y.) (01.04.2013)
Published in Diabetes (New York, N.Y.) (01.04.2013)
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Journal Article
Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program
Frye, Maike, Taddei, Andrea, Dierkes, Cathrin, Martinez-Corral, Ines, Fielden, Matthew, Ortsäter, Henrik, Kazenwadel, Jan, Calado, Dinis P., Ostergaard, Pia, Salminen, Marjo, He, Liqun, Harvey, Natasha L., Kiefer, Friedemann, Mäkinen, Taija
Published in Nature communications (17.04.2018)
Published in Nature communications (17.04.2018)
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Journal Article
Differentiating between effects of streptozotocin per se and subsequent hyperglycemia on renal function and metabolism in the streptozotocin-diabetic rat model
Palm, Fredrik, Ortsäter, Henrik, Hansell, Peter, Liss, Per, Carlsson, Per-Ola
Published in Diabetes/metabolism research and reviews (01.11.2004)
Published in Diabetes/metabolism research and reviews (01.11.2004)
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Journal Article
Glucagon-like peptide-1 receptor activation reduces ischaemic brain damage following stroke in Type 2 diabetic rats
Darsalia, Vladimer, Mansouri, Shiva, Ortsäter, Henrik, Olverling, Anna, Nozadze, Nino, Kappe, Camilla, Iverfeldt, Kerstin, Tracy, Linda M, Grankvist, Nina, Sjöholm, Åke, Patrone, Cesare
Published in Clinical science (1979) (01.05.2012)
Published in Clinical science (1979) (01.05.2012)
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Journal Article
Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity
Wang, Yixin, Jin, Yi, Mäe, Maarja Andaloussi, Zhang, Yang, Ortsäter, Henrik, Betsholtz, Christer, Mäkinen, Taija, Jakobsson, Lars
Published in Development (Cambridge) (01.10.2017)
Published in Development (Cambridge) (01.10.2017)
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Journal Article
EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity
Frye, Maike, Stritt, Simon, Ortsäter, Henrik, Hernandez Vasquez, Magda, Kaakinen, Mika, Vicente, Andres, Wiseman, John, Eklund, Lauri, Martínez-Torrecuadrada, Jorge L, Vestweber, Dietmar, Mäkinen, Taija
Published in eLife (08.09.2020)
Published in eLife (08.09.2020)
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Journal Article
Short-term glucocorticoid treatment increases insulin secretion in islets derived from lean mice through multiple pathways and mechanisms
Hult, Malin, Ortsäter, Henrik, Schuster, Gertrud, Graedler, Florian, Beckers, Johannes, Adamski, Jerzy, Ploner, Alexander, Jörnvall, Hans, Bergsten, Peter, Oppermann, Udo
Published in Molecular and cellular endocrinology (25.03.2009)
Published in Molecular and cellular endocrinology (25.03.2009)
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Journal Article
Coadministration of sitagliptin or metformin has no major impact on the adverse metabolic outcomes induced by dexamethasone treatment in rats
Figueiredo, Bryanne Silva, Ferreira, Francielle Batista D., Barbosa, Amanda Marreiro, dos Santos, Cristiane, Ortsäter, Henrik, Rafacho, Alex
Published in Life sciences (1973) (01.12.2021)
Published in Life sciences (1973) (01.12.2021)
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Journal Article
Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes
Hagberg, Carolina E., Mehlem, Annika, Falkevall, Annelie, Muhl, Lars, Fam, Barbara C., Ortsäter, Henrik, Scotney, Pierre, Nyqvist, Daniel, Samén, Erik, Lu, Li, Stone-Elander, Sharon, Proietto, Joseph, Andrikopoulos, Sofianos, Sjöholm, Åke, Nash, Andrew, Eriksson, Ulf
Published in Nature (London) (18.10.2012)
Published in Nature (London) (18.10.2012)
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Journal Article
The DPP-4 Inhibitor Linagliptin Counteracts Stroke in the Normal and Diabetic Mouse Brain: A Comparison With Glimepiride
DARSALIA, Vladimer, ORTSÄTER, Henrik, OLVERLING, Anna, DARLÖF, Emilia, WOLBERT, Petra, NYSTRÖM, Thomas, KLEIN, Thomas, SJÖHOLM, Ake, PATRONE, Cesare
Published in Diabetes (New York, N.Y.) (01.04.2013)
Published in Diabetes (New York, N.Y.) (01.04.2013)
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Journal Article
Inorganic nitrite stimulates pancreatic islet blood flow and insulin secretion
Nyström, Thomas, Ortsäter, Henrik, Huang, Zhen, Zhang, Fan, Larsen, Filip J., Weitzberg, Eddie, Lundberg, Jon O., Sjöholm, Åke
Published in Free radical biology & medicine (01.09.2012)
Published in Free radical biology & medicine (01.09.2012)
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Journal Article