Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease
Linsel-Nitschke, Patrick, Heeren, Jörg, Aherrahrou, Zouhair, Bruse, Petra, Gieger, Christian, Illig, Thomas, Prokisch, Holger, Heim, Katharina, Doering, Angela, Peters, Annette, Meitinger, Thomas, Wichmann, H.-Erich, Hinney, Anke, Reinehr, Thomas, Roth, Christian, Ortlepp, Jan. R, Soufi, Mouhidien, Sattler, Alexander M, Schaefer, Jürgen, Stark, Klaus, Hengstenberg, Christian, Schaefer, Arne, Schreiber, Stefan, Kronenberg, Florian, Samani, Nilesh J, Schunkert, Heribert, Erdmann, Jeanette
Published in Atherosclerosis (01.01.2010)
Published in Atherosclerosis (01.01.2010)
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Journal Article
Prevalence and Strain Characterization of Clostridioides (Clostridium) difficile in Representative Regions of Germany, Ghana, Tanzania and Indonesia - A Comparative Multi-Center Cross-Sectional Study
Seugendo, Mwanaisha, Janssen, Iryna, Lang, Vanessa, Hasibuan, Irene, Bohne, Wolfgang, Cooper, Paul, Daniel, Rolf, Gunka, Katrin, Kusumawati, R L, Mshana, Stephen E, von Müller, Lutz, Okamo, Benard, Ortlepp, Jan R, Overmann, Jörg, Riedel, Thomas, Rupnik, Maja, Zimmermann, Ortrud, Groß, Uwe
Published in Frontiers in microbiology (07.08.2018)
Published in Frontiers in microbiology (07.08.2018)
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Journal Article
Antibiotic Stewardship - From Bench to Bedside
Ortlepp, Jan R
Published in Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS (01.04.2017)
Published in Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS (01.04.2017)
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Journal Article
Genetic Analysis of the Angiotensinogen Gene in Pre-Eclampsia: Study of German Women and Review of the Literature
Knyrim, Elke, Muetze, Sabine, Eggermann, Thomas, Rudnik-Schoeneborn, Sabine, Lindt, Ria, Ortlepp, Jan R., Rath, Werner, Zerres, Klaus
Published in Gynecologic and obstetric investigation (01.01.2008)
Published in Gynecologic and obstetric investigation (01.01.2008)
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Journal Article
A double-blind, randomized, placebo-controlled multicenter clinical trial to evaluate the effects of the angiotensin II receptor blocker candesartan cilexetil on intimal hyperplasia after coronary stent implantation
Radke, Peter W., Figulla, Hans R., Drexler, Helmut, Klues, Heinrich G., Mügge, Andreas, Silber, Sigmund, Daniel, Werner, Schmeisser, Alexander, Reifart, Nicolaus, Motz, Wolfgang, Büttner, Hans-Joachim, Fischer, Dieter, Ortlepp, Jan R., Schaefers, Kerstin, Hoffmann, Rainer, Hanrath, Peter
Published in The American heart journal (01.10.2006)
Published in The American heart journal (01.10.2006)
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Journal Article
The Reduction in Antibiotic Use in Hospitals
Scholze, Karen, Wenke, Mechthild, Schierholz, Reinhard, Groß, Uwe, Bader, Oliver, Zimmermann, Ortrud, Lemmen, Sebastian, Ortlepp, Jan R
Published in Deutsches Ärzteblatt international (16.10.2015)
Published in Deutsches Ärzteblatt international (16.10.2015)
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Journal Article
Parathyroid hormone gene variant and calcific aortic stenosis
Schmitz, Fabian, Ewering, Silke, Zerres, Klaus, Klomfass, Sebastian, Hoffmann, Rainer, Ortlepp, Jan R
Published in The Journal of heart valve disease (01.05.2009)
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Published in The Journal of heart valve disease (01.05.2009)
Journal Article
Systemic and local levels of fetuin-A in calcific aortic valve stenosis
Kaden, Jens, Reinöhl, Jochen, Blesch, Birgit, Brueckmann, Martina, Haghi, Dariusch, Borggrefe, Martin, Schmitz, Fabian, Klomfass, Sebastian, Pillich, Manuela, Ortlepp, Jan
Published in International journal of molecular medicine (01.08.2007)
Published in International journal of molecular medicine (01.08.2007)
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Journal Article
The amount of calcium-deficient hexagonal hydroxyapatite in aortic valves is influenced by gender and associated with genetic polymorphisms in patients with severe calcific aortic stenosis
Ortlepp, Jan R, Schmitz, Fabian, Mevissen, Vera, Weiß, Stefan, Huster, Jürgen, Dronskowski, Richard, Langebartels, Georg, Autschbach, Rüdiger, Zerres, Klaus, Weber, Christian, Hanrath, Peter, Hoffmann, Rainer
Published in European heart journal (01.03.2004)
Published in European heart journal (01.03.2004)
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Journal Article
Maternal factor V Leiden mutation is associated with HELLP syndrome in Caucasian women
Muetze, Sabine, Leeners, Brigitte, Ortlepp, Jan R., Kuse, Sabine, Tag, Carmen G., Weiskirchen, Ralf, Gressner, Axel M., Rudnik-Schoeneborn, Sabine, Zerres, Klaus, Rath, Werner
Published in Acta obstetricia et gynecologica Scandinavica (01.01.2008)
Published in Acta obstetricia et gynecologica Scandinavica (01.01.2008)
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Journal Article
Chemokine receptor (CCR2) genotype is associated with myocardial infarction and heart failure in patients under 65 years of age
ORTLEPP, Jan R, VESPER, Katharina, MEVISSEN, Vera, SCHMITZ, Fabian, JANSSENS, Uwe, FRANKE, Andreas, HANRATH, Peter, WEBER, Christian, ZERRES, Klaus, HOFFMANN, Rainer
Published in Journal of molecular medicine (Berlin, Germany) (01.06.2003)
Published in Journal of molecular medicine (Berlin, Germany) (01.06.2003)
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Journal Article
Variants of the CYP11B2 gene predict response to therapy with candesartan
Ortlepp, Jan R, Hanrath, Peter, Mevissen, Vera, Kiel, Gerhard, Borggrefe, Martin, Hoffmann, Rainer
Published in European journal of pharmacology (07.06.2002)
Published in European journal of pharmacology (07.06.2002)
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Journal Article
Quantification of aortic valve calcification using multislice spiral computed tomography: comparison with atomic absorption spectroscopy
Koos, Ralf, Mahnken, Andreas Horst, Kühl, Harald Peter, Mühlenbruch, Georg, Mevissen, Vera, Stork, Ludwig, Dronskowski, Richard, Langebartels, Georg, Autschbach, Rüdiger, Ortlepp, Jan R
Published in Investigative radiology (01.05.2006)
Published in Investigative radiology (01.05.2006)
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Journal Article
Additive effects of the chemokine receptor 2, vitamin D receptor, interleukin-6 polymorphisms and cardiovascular risk factors on the prevalence of myocardial infarction in patients below 65 years
Ortlepp, Jan R., Krantz, Constanze, Kimmel, Melanie, von Korff, Alexei, Vesper, Katharina, Schmitz, Fabian, Mevissen, Vera, Janssens, Uwe, Franke, Andreas, Hanrath, Peter, Zerres, Klaus, Hoffmann, Rainer
Published in International journal of cardiology (20.10.2005)
Published in International journal of cardiology (20.10.2005)
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Journal Article
Obesity is associated with a slower response to initial phenprocoumon therapy whereas CYP2C9 genotypes are not
ZU SCHWABEDISSEN, Cordula Meyer, MEVISSEN, Vera, SCHMITZ, Fabian, WOODRUFF, Seth, LANGEBARTELS, Georg, RAU, Thomas, ZERRES, Klaus, HOFFMANN, Rainer, ORTLEPP, Jan R
Published in European journal of clinical pharmacology (01.09.2006)
Published in European journal of clinical pharmacology (01.09.2006)
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Journal Article
Lower serum calcium levels are associated with greater calcium hydroxyapatite deposition in native aortic valves of male patients with severe calcific aortic stenosis
Ortlepp, Jan R, Pillich, Manuela, Schmitz, Fabian, Mevissen, Vera, Koos, Ralf, Weiss, Stefan, Stork, Ludwig, Dronskowski, Richard, Langebartels, Georg, Autschbach, Rüdiger, Brandenburg, Vincent, Woodruff, Seth, Kaden, Jens J, Hoffmann, Rainer
Published in The Journal of heart valve disease (01.07.2006)
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Published in The Journal of heart valve disease (01.07.2006)
Journal Article
Cardiovascular risk factors in patients with aortic stenosis are associated with the prevalence of coronary artery disease, but not the prevalence of aortic stenosis
Ortlepp, Jan R., Schmitz, Fabian, Mevissen, Vera, Bozoglu, Tolga, Hanrath, Peter, Hoffman, Rainer
Published in Journal of the American College of Cardiology (19.03.2003)
Published in Journal of the American College of Cardiology (19.03.2003)
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Journal Article