Distinct ubiquitin binding modes exhibited by SH3 domains: molecular determinants and functional implications
Ortega Roldan, Jose L, Casares, Salvador, Ringkjøbing Jensen, Malene, Cárdenes, Nayra, Bravo, Jerónimo, Blackledge, Martin, Azuaga, Ana I, van Nuland, Nico A J
Published in PloS one (11.09.2013)
Published in PloS one (11.09.2013)
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Journal Article
Multimeric and differential binding of CIN85/CD2AP with two atypical proline‐rich sequences from CD2 and Cbl‐b
Ceregido, M. Angeles, Garcia‐Pino, Abel, Ortega‐Roldan, Jose L, Casares, Salvador, López Mayorga, Obdulio, Bravo, Jeronimo, Nuland, Nico A. J, Azuaga, Ana I
Published in The FEBS journal (01.07.2013)
Published in The FEBS journal (01.07.2013)
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Journal Article
Solution structure, dynamics and thermodynamics of the three SH3 domains of CD2AP
Roldan, Jose L. Ortega, Blackledge, Martin, van Nuland, Nico A. J., Azuaga, Ana I.
Published in Journal of biomolecular NMR (01.06.2011)
Published in Journal of biomolecular NMR (01.06.2011)
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Journal Article
Structure-based discovery and in vitro validation of inhibitors of chloride intracellular channel 4 protein
Olotu, Fisayo, Medina-Carmona, Encarnacion, Serrano-Sanchez, Angela, Ossa, Felipe, El-Hamdaoui, Abdelaziz, Bishop, Özlem Tastan, Ortega-Roldan, Jose L., Abdul-Salam, Vahitha B.
Published in Computational and structural biotechnology journal (01.01.2023)
Published in Computational and structural biotechnology journal (01.01.2023)
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Journal Article
The elucidation of phospholipid bilayer-small molecule interactions using a combination of phospholipid nanodiscs and solution state NMR techniques
Townshend, Georgina, Thompson, Gary S, White, Lisa J, Hiscock, Jennifer R, Ortega-Roldan, Jose L
Published in Chemical communications (Cambridge, England) (11.04.2020)
Published in Chemical communications (Cambridge, England) (11.04.2020)
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Journal Article
A solution NMR methodology enabling the elucidation of small molecule phospholipid membrane adhesion and passive permeation parameters
Serrano-Sanchez, Angela, Rice, Matthew, Cassar, Joseph, White, Lisa J, Popoola, Precious I A, Thompson, Gary S, Hiscock, Jennifer R, Ortega-Roldan, Jose L
Published in Chemical communications (Cambridge, England) (01.10.2024)
Published in Chemical communications (Cambridge, England) (01.10.2024)
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Journal Article
A Zn2+-triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels
Varela, Lorena, Hendry, Alex C., Cassar, Joseph, Martin-Escolano, Ruben, Cantoni, Diego, Ossa, Felipe, Edwards, John C., Abdul-Salam, Vahitha, Ortega-Roldan, Jose L.
Published in Journal of cell science (01.08.2022)
Published in Journal of cell science (01.08.2022)
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Journal Article
Phospholipid headgroup composition modulates the molecular interactions and antimicrobial effects of sulfobetaine zwitterionic detergents against the "ESKAPE" pathogen Pseudomonas aeruginosa
Hilton, Kira L F, Tolley, Howard, Ortega-Roldan, Jose L, Thompson, Gary S, Sutton, J Mark, Hind, Charlotte K, Hiscock, Jennifer R
Published in Chemical communications (Cambridge, England) (29.08.2023)
Published in Chemical communications (Cambridge, England) (29.08.2023)
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A quantitative assay to study the lipid selectivity of membrane-associated systems using solution NMR
Medina-Carmona, Encarnacion, Varela, Lorena, Hendry, Alex C, Thompson, Gary S, White, Lisa J, Boles, Jessica E, Hiscock, Jennifer R, Ortega-Roldan, Jose L
Published in Chemical communications (Cambridge, England) (07.10.2020)
Published in Chemical communications (Cambridge, England) (07.10.2020)
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Journal Article
Discovery and Rational Mutagenesis of Methionine Sulfoxide Reductase Biocatalysts To Expand the Substrate Scope of the Kinetic Resolution of Chiral Sulfoxides
Anselmi, Silvia, Carvalho, Alexandra T. P., Serrano-Sanchez, Angela, Ortega-Roldan, Jose L., Caswell, Jill, Omar, Iman, Perez-Ortiz, Gustavo, Barry, Sarah M., Moody, Thomas S., Castagnolo, Daniele
Published in ACS catalysis (07.04.2023)
Published in ACS catalysis (07.04.2023)
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Journal Article
Establishing the selective phospholipid membrane coordination, permeation and lysis properties for a series of 'druggable' supramolecular self-associating antimicrobial amphiphiles
Boles, Jessica E, Bennett, Charlotte, Baker, Jennifer, Hilton, Kira L. F, Kotak, Hiral A, Clark, Ewan R, Long, Yifan, White, Lisa J, Lai, Hin Yuk, Hind, Charlotte K, Sutton, J. Mark, Garrett, Michelle D, Cheasty, Anne, Ortega-Roldan, Jose L, Charles, Mark, Haynes, Cally J. E, Hiscock, Jennifer R
Published in Chemical science (Cambridge) (24.08.2022)
Published in Chemical science (Cambridge) (24.08.2022)
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Journal Article
high resolution NMR structure of the third SH3 domain of CD2AP
Ortega Roldan, Jose L, Romero Romero, M. Luisa, Ora, Ari, AB, Eiso, Lopez Mayorga, Obdulio, Azuaga, Ana I, van Nuland, Nico A. J
Published in Journal of biomolecular NMR (01.12.2007)
Published in Journal of biomolecular NMR (01.12.2007)
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Journal Article
Phospholipid headgroup composition modulates the molecular interactions and antimicrobial effects of sulfobetaine zwitterionic detergents against the "ESKAPE" pathogen
Hilton, Kira L. F, Tolley, Howard, Ortega-Roldan, Jose L, Thompson, Gary S, Sutton, J. Mark, Hind, Charlotte K, Hiscock, Jennifer R
Published in Chemical communications (Cambridge, England) (29.08.2023)
Published in Chemical communications (Cambridge, England) (29.08.2023)
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Journal Article
Multimeric and differential binding of CIN 85/ CD 2 AP with two atypical proline‐rich sequences from CD 2 and Cbl‐b
Ceregido, M. Angeles, Garcia‐Pino, Abel, Ortega‐Roldan, Jose L., Casares, Salvador, López Mayorga, Obdulio, Bravo, Jeronimo, van Nuland, Nico A. J., Azuaga, Ana I.
Published in The FEBS journal (01.07.2013)
Published in The FEBS journal (01.07.2013)
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Journal Article
Structure-based discovery and in vitro validation of selective inhibitors of Chloride Intracellular Channel 4 protein
Olotu, Fisayo, Medina-Carmona, Encarnacion, El-Hamdaoui, Abdelaziz, Bishop, Ozlem Tastan, Ortega-Roldan, Jose L, Abdul-Salam, Vahitha B
Published in bioRxiv (22.04.2022)
Published in bioRxiv (22.04.2022)
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