Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation
Groth, Petra, Orta, Manuel Luís, Elvers, Ingegerd, Majumder, Muntasir Mamun, Lagerqvist, Anne, Helleday, Thomas
Published in Nucleic acids research (01.08.2012)
Published in Nucleic acids research (01.08.2012)
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Journal Article
Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair
Petermann, Eva, Orta, Manuel Luís, Issaeva, Natalia, Schultz, Niklas, Helleday, Thomas
Published in Molecular cell (26.02.2010)
Published in Molecular cell (26.02.2010)
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Journal Article
Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors
Hajji, Nabil, Garcia-Revilla, Juan, Soto, Manuel Sarmiento, Perryman, Richard, Symington, Jake, Quarles, Chad C, Healey, Deborah R, Guo, Yijie, Orta-Vázquez, Manuel Luis, Mateos-Cordero, Santiago, Shah, Khalid, Bomalaski, John, Anichini, Giulio, Tzakos, Andreas G, Crook, Timothy, O'Neill, Kevin, Scheck, Adrienne C, Venero, Jose Luis, Syed, Nelofer
Published in The Journal of clinical investigation (15.03.2022)
Published in The Journal of clinical investigation (15.03.2022)
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Journal Article
5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair
Orta, Manuel Luís, Calderón-Montaño, José Manuel, Domínguez, Inmaculada, Pastor, Nuria, Burgos-Morón, Estefanía, López-Lázaro, Miguel, Cortés, Felipe, Mateos, Santiago, Helleday, Thomas
Published in Nucleic acids research (01.06.2013)
Published in Nucleic acids research (01.06.2013)
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Journal Article
Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death
Calderón-Montaño, José Manuel, Burgos-Morón, Estefanía, Orta, Manuel Luis, Pastor, Nuria, Austin, Caroline A., Mateos, Santiago, López-Lázaro, Miguel
Published in Toxicology letters (12.09.2013)
Published in Toxicology letters (12.09.2013)
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Journal Article
Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
Burgos-Morón, Estefanía, Calderón-Montaño, José Manuel, Orta, Manuel Luis, Guillén-Mancina, Emilio, Mateos, Santiago, López-Lázaro, Miguel
Published in Toxins (08.07.2016)
Published in Toxins (08.07.2016)
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Journal Article
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions
Orta, Manuel Luis, Höglund, Andreas, Calderón-Montaño, José Manuel, Domínguez, Inmaculada, Burgos-Morón, Estefanía, Visnes, Torkild, Pastor, Nuria, Ström, Cecilia, López-lázaro, Miguel, Helleday, Thomas
Published in Nucleic acids research (18.08.2014)
Published in Nucleic acids research (18.08.2014)
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Journal Article
Metabolic Disturbance of High-Saturated Fatty Acid Diet in Cognitive Preservation
Rivas-Domínguez, Antonio, Mohamed-Mohamed, Himan, Jimenez-Palomares, Margarita, García-Morales, Victoria, Martinez-Lopez, Laura, Orta, Manuel Luis, Ramos-Rodriguez, Juan José, Bermudez-Pulgarin, Beatriz
Published in International journal of molecular sciences (28.04.2023)
Published in International journal of molecular sciences (28.04.2023)
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Journal Article
The Coffee Constituent Chlorogenic Acid Induces Cellular DNA Damage and Formation of Topoisomerase I– and II–DNA Complexes in Cells
Burgos-Morón, Estefanía, Calderón-Montaño, José Manuel, Orta, Manuel Luis, Pastor, Nuria, Pérez-Guerrero, Concepción, Austin, Caroline, Mateos, Santiago, López-Lázaro, Miguel
Published in Journal of agricultural and food chemistry (01.08.2012)
Published in Journal of agricultural and food chemistry (01.08.2012)
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Journal Article
A hydroalcoholic extract from the leaves of Nerium oleander inhibits glycolysis and induces selective killing of lung cancer cells
Calderón-Montaño, José Manuel, Burgos-Morón, Estefanía, Orta, Manuel Luis, Mateos, Santiago, López-Lázaro, Miguel
Published in Planta medica (01.08.2013)
Published in Planta medica (01.08.2013)
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Journal Article
Selective Cytotoxic Activity of New Lipophilic Hydroxytyrosol Alkyl Ether Derivatives
Calderón-Montaño, José Manuel, Madrona, Andrés, Burgos-Morón, Estefanía, Orta, Manuel Luis, Mateos, Santiago, Espartero, José Luis, López-Lázaro, Miguel
Published in Journal of agricultural and food chemistry (29.05.2013)
Published in Journal of agricultural and food chemistry (29.05.2013)
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Journal Article
Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination
Orta, Manuel Luis, Pastor, Nuria, Burgos-Morón, Estefanía, Domínguez, Inmaculada, Calderón-Montaño, José Manuel, Huertas Castaño, Carlos, López-Lázaro, Miguel, Helleday, Thomas, Mateos, Santiago
Published in DNA repair (01.09.2017)
Published in DNA repair (01.09.2017)
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Journal Article
In Vitro Anticancer Activity and Mechanism of Action of an Aziridinyl Galactopyranoside
Burgos-Morón, Estefanía, Pastor, Nuria, Orta, Manuel Luis, Jiménez-Alonso, Julio José, Palo-Nieto, Carlos, Vega-Holm, Margarita, Vega-Pérez, José Manuel, Iglesias-Guerra, Fernando, Mateos, Santiago, López-Lázaro, Miguel, Calderón-Montaño, José Manuel
Published in Biomedicines (01.01.2022)
Published in Biomedicines (01.01.2022)
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Journal Article
Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside
Burgos‐Morón, Estefanía, Pastor, Nuria, Orta, Manuel Luis, Jiménez‐Alonso, Julio José, Vega‐Holm, Margarita, Vega‐Pérez, José Manuel, Iglesias‐Guerra, Fernando, Mateos, Santiago, López‐Lázaro, Miguel, Calderón‐Montaño, José Manuel
Published in Drug development research (01.12.2018)
Published in Drug development research (01.12.2018)
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Journal Article
Protection of halogenated DNA from strand breakage and sister-chromatid exchange induced by the topoisomerase I inhibitor camptothecin
Orta, Manuel Luís, Mateos, Santiago, Cantero, Gloria, Wolff, Lisa J, Cortés, Felipe
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (01.01.2008)
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (01.01.2008)
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Journal Article