The BiTE (bispecific T‐cell engager) platform: Development and future potential of a targeted immuno‐oncology therapy across tumor types
Einsele, Hermann, Borghaei, Hossein, Orlowski, Robert Z., Subklewe, Marion, Roboz, Gail J., Zugmaier, Gerhard, Kufer, Peter, Iskander, Karim, Kantarjian, Hagop M.
Published in Cancer (15.07.2020)
Published in Cancer (15.07.2020)
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Bortezomib with lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone in patients with newly diagnosed myeloma without intent for immediate autologous stem-cell transplant (SWOG S0777): a randomised, open-label, phase 3 trial
Durie, Brian G M, Dr Prof, Hoering, Antje, PhD, Abidi, Muneer H, MD, Rajkumar, S Vincent, Prof, Epstein, Joshua, Prof, Kahanic, Stephen P, MD, Thakuri, Mohan, MD, Reu, Frederic, MD, Reynolds, Christopher M, MD, Sexton, Rachael, MS, Orlowski, Robert Z, Prof, Barlogie, Bart, Prof, Dispenzieri, Angela, Prof
Published in The Lancet (British edition) (04.02.2017)
Published in The Lancet (British edition) (04.02.2017)
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Daratumumab, lenalidomide, bortezomib, and dexamethasone for transplant-eligible newly diagnosed multiple myeloma: the GRIFFIN trial
Voorhees, Peter M., Kaufman, Jonathan L., Laubach, Jacob, Sborov, Douglas W., Reeves, Brandi, Rodriguez, Cesar, Chari, Ajai, Silbermann, Rebecca, Costa, Luciano J., Anderson, Larry D., Nathwani, Nitya, Shah, Nina, Efebera, Yvonne A., Holstein, Sarah A., Costello, Caitlin, Jakubowiak, Andrzej, Wildes, Tanya M., Orlowski, Robert Z., Shain, Kenneth H., Cowan, Andrew J., Murphy, Sean, Lutska, Yana, Pei, Huiling, Ukropec, Jon, Vermeulen, Jessica, de Boer, Carla, Hoehn, Daniela, Lin, Thomas S., Richardson, Paul G.
Published in Blood (20.08.2020)
Published in Blood (20.08.2020)
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Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group
Palumbo, Antonio, Avet-Loiseau, Hervé, Oliva, Stefania, Lokhorst, Henk M, Goldschmidt, Hartmut, Rosinol, Laura, Richardson, Paul, Caltagirone, Simona, Lahuerta, Juan José, Facon, Thierry, Bringhen, Sara, Gay, Francesca, Attal, Michel, Passera, Roberto, Spencer, Andrew, Offidani, Massimo, Kumar, Shaji, Musto, Pellegrino, Lonial, Sagar, Petrucci, Maria T, Orlowski, Robert Z, Zamagni, Elena, Morgan, Gareth, Dimopoulos, Meletios A, Durie, Brian G M, Anderson, Kenneth C, Sonneveld, Pieter, San Miguel, Jésus, Cavo, Michele, Rajkumar, S Vincent, Moreau, Philippe
Published in Journal of clinical oncology (10.09.2015)
Published in Journal of clinical oncology (10.09.2015)
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Proteasome inhibitors in multiple myeloma: 10 years later
Moreau, Philippe, Richardson, Paul G., Cavo, Michele, Orlowski, Robert Z., San Miguel, Jesús F., Palumbo, Antonio, Harousseau, Jean-Luc
Published in Blood (02.08.2012)
Published in Blood (02.08.2012)
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Carfilzomib, pomalidomide, and dexamethasone for relapsed or refractory myeloma
Shah, Jatin J., Stadtmauer, Edward A., Abonour, Rafat, Cohen, Adam D., Bensinger, William I., Gasparetto, Cristina, Kaufman, Jonathan L., Lentzsch, Suzanne, Vogl, Dan T., Gomes, Christina L., Pascucci, Natalia, Smith, David D., Orlowski, Robert Z., Durie, BrianG.M.
Published in Blood (12.11.2015)
Published in Blood (12.11.2015)
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Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
Zhu, Yuan Xiao, Braggio, Esteban, Shi, Chang-Xin, Bruins, Laura A., Schmidt, Jessica E., Van Wier, Scott, Chang, Xiu-Bao, Bjorklund, Chad C., Fonseca, Rafael, Bergsagel, P. Leif, Orlowski, Robert Z., Stewart, A. Keith
Published in Blood (03.11.2011)
Published in Blood (03.11.2011)
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Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
Li, Zongwei, Liu, Huan, He, Jin, Wang, Zhiqiang, Yin, Zheng, You, Gichun, Wang, Zhiming, Davis, Richard E., Lin, Pei, Bergsagel, P. Leif, Manasanch, Elisabet E., Wong, Stephen T.C., Esnaola, Nestor F., Chang, Jenny C., Orlowski, Robert Z., Yi, Qing, Yang, Jing
Published in Cell metabolism (05.01.2021)
Published in Cell metabolism (05.01.2021)
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Clinical and pathological characteristics of HIV- and HHV-8–negative Castleman disease
Yu, Li, Tu, Meifeng, Cortes, Jorge, Xu-Monette, Zijun Y., Miranda, Roberto N., Zhang, Jun, Orlowski, Robert Z., Neelapu, Sattva, Boddu, Prajwal C., Akosile, Mary A., Uldrick, Thomas S., Yarchoan, Robert, Medeiros, L.Jeffrey, Li, Yong, Fajgenbaum, David C., Young, Ken H.
Published in Blood (23.03.2017)
Published in Blood (23.03.2017)
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Prospective analysis of antigen-specific immunity, stem-cell antigens, and immune checkpoints in monoclonal gammopathy
Dhodapkar, Madhav V., Sexton, Rachael, Das, Rituparna, Dhodapkar, Kavita M., Zhang, Lin, Sundaram, Ranjini, Soni, Sonal, Crowley, John J., Orlowski, Robert Z., Barlogie, Bart
Published in Blood (26.11.2015)
Published in Blood (26.11.2015)
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International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation
PALUMBO, Antonio, VINCENT RAJKUMAR, S, DIMOPOULOS, Meletios A, RICHARDSON, Paul G, CAVO, Michele, SPENCER, Andrew, KEITH STEWART, A, SHIMIZU, Kazuyuki, LONIAL, Sagar, SONNEVELD, Pieter, DURIE, Brian G. M, MOREAU, Philippe, SAN MIGUEL, Jesus F, ORLOWSKI, Robert Z, LAROCCA, Alessandra, NIESVIZKY, Ruben, MORGAN, Gareth, LANDGREN, Ola, HAJEK, Roman, EINSELE, Hermann, ANDERSON, Kenneth C
Published in Journal of clinical oncology (20.02.2014)
Published in Journal of clinical oncology (20.02.2014)
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Osteoblastic niche supports the growth of quiescent multiple myeloma cells
Chen, Zheng, Orlowski, Robert Z., Wang, Michael, Kwak, Larry, McCarty, Nami
Published in Blood (03.04.2014)
Published in Blood (03.04.2014)
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Phase 2 dose-expansion study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma
Wang, Michael, Martin, Tom, Bensinger, William, Alsina, Melissa, Siegel, David S., Kavalerchik, Edward, Huang, Mei, Orlowski, Robert Z., Niesvizky, Ruben
Published in Blood (31.10.2013)
Published in Blood (31.10.2013)
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Safety and activity of lenalidomide and rituximab in untreated indolent lymphoma: an open-label, phase 2 trial
Fowler, Nathan H, Dr, Davis, R Eric, MD, Rawal, Seema, PhD, Nastoupil, Loretta, MD, Hagemeister, Fredrick B, Prof, McLaughlin, Peter, Prof, Kwak, Larry W, Prof, Romaguera, Jorge E, Prof, Fanale, Michelle A, MD, Fayad, Luis E, MD, Westin, Jason R, MD, Shah, Jatin, MD, Orlowski, Robert Z, Prof, Wang, Michael, Prof, Turturro, Francesco, Prof, Oki, Yasuhiro, MD, Claret, Linda C, RN, Feng, Lei, MS, Baladandayuthapani, Veerabhadran, PhD, Muzzafar, Tariq, MD, Tsai, Kenneth Y, MD, Samaniego, Felipe, MD, Neelapu, Sattva S, MD
Published in The lancet oncology (01.11.2014)
Published in The lancet oncology (01.11.2014)
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Leukocyte immunoglobulin-like receptor B1 (LILRB1) protects human multiple myeloma cells from ferroptosis by maintaining cholesterol homeostasis
Xian, Miao, Wang, Qiang, Xiao, Liuling, Zhong, Ling, Xiong, Wei, Ye, Lingqun, Su, Pan, Zhang, Chuanchao, Li, Yabo, Orlowski, Robert Z., Zhan, Fenghuang, Ganguly, Siddhartha, Zu, Youli, Qian, Jianfei, Yi, Qing
Published in Nature communications (09.07.2024)
Published in Nature communications (09.07.2024)
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A Phase 1 Dose Escalation Study of the Safety and Pharmacokinetics of the Novel Proteasome Inhibitor Carfilzomib (PR-171) in Patients with Hematologic Malignancies
O'Connor, Owen A., Stewart, A. Keith, Vallone, Marcy, Molineaux, Christopher J., Kunkel, Lori A., Gerecitano, John F., Orlowski, Robert Z.
Published in Clinical cancer research (15.11.2009)
Published in Clinical cancer research (15.11.2009)
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Ubiquitin-activating enzyme inhibition induces an unfolded protein response and overcomes drug resistance in myeloma
Zhuang, Junling, Shirazi, Fazal, Singh, Ram Kumar, Kuiatse, Isere, Wang, Hua, Lee, Hans C., Berkova, Zuzana, Berger, Allison, Hyer, Marc, Chattopadhyay, Nibedita, Syed, Sakeena, Shi, Judy Qiuju, Yu, Jie, Shinde, Vaishali, Tirrell, Stephen, Jones, Richard Julian, Wang, Zhiqiang, Davis, R. Eric, Orlowski, Robert Z.
Published in Blood (04.04.2019)
Published in Blood (04.04.2019)
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