Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
Whyte, Warren A., Orlando, David A., Hnisz, Denes, Abraham, Brian J., Lin, Charles Y., Kagey, Michael H., Rahl, Peter B., Lee, Tong Ihn, Young, Richard A.
Published in Cell (11.04.2013)
Published in Cell (11.04.2013)
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Journal Article
Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
Lovén, Jakob, Hoke, Heather A., Lin, Charles Y., Lau, Ashley, Orlando, David A., Vakoc, Christopher R., Bradner, James E., Lee, Tong Ihn, Young, Richard A.
Published in Cell (11.04.2013)
Published in Cell (11.04.2013)
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Journal Article
Revisiting Global Gene Expression Analysis
Lovén, Jakob, Orlando, David A., Sigova, Alla A., Lin, Charles Y., Rahl, Peter B., Burge, Christopher B., Levens, David L., Lee, Tong Ihn, Young, Richard A.
Published in Cell (26.10.2012)
Published in Cell (26.10.2012)
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Journal Article
Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling
Mullen, Alan C., Orlando, David A., Newman, Jamie J., Lovén, Jakob, Kumar, Roshan M., Bilodeau, Steve, Reddy, Jessica, Guenther, Matthew G., DeKoter, Rodney P., Young, Richard A.
Published in Cell (28.10.2011)
Published in Cell (28.10.2011)
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Journal Article
Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome
Orlando, David A., Chen, Mei Wei, Brown, Victoria E., Solanki, Snehakumari, Choi, Yoon J., Olson, Eric R., Fritz, Christian C., Bradner, James E., Guenther, Matthew G.
Published in Cell reports (Cambridge) (06.11.2014)
Published in Cell reports (Cambridge) (06.11.2014)
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Journal Article
Global Transcriptional and Translational Repression in Human-Embryonic-Stem-Cell-Derived Rett Syndrome Neurons
Li, Yun, Wang, Haoyi, Muffat, Julien, Cheng, Albert W., Orlando, David A., Lovén, Jakob, Kwok, Show-ming, Feldman, Danielle A., Bateup, Helen S., Gao, Qing, Hockemeyer, Dirk, Mitalipova, Maisam, Lewis, Caroline A., Vander Heiden, Matthew G., Sur, Mriganka, Young, Richard A., Jaenisch, Rudolf
Published in Cell stem cell (03.10.2013)
Published in Cell stem cell (03.10.2013)
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Journal Article
Mediator and cohesin connect gene expression and chromatin architecture
Taatjes, Dylan J, van Berkum, Nynke L, Young, Richard A, Kagey, Michael H, Bilodeau, Steve, Zhan, Ye, Ebmeier, Christopher C, Levine, Stuart S, Newman, Jamie J, Rahl, Peter B, Dekker, Job, Goossens, Jesse, Orlando, David A
Published in Nature (London) (23.09.2010)
Published in Nature (London) (23.09.2010)
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Journal Article
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells
Sigova, Alla A., Mullen, Alan C., Molinie, Benoit, Gupta, Sumeet, Orlando, David A., Guenther, Matthew G., Almada, Albert E., Lin, Charles, Sharp, Phillip A., Giallourakis, Cosmas C., Young, Richard A.
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2013)
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Journal Article
Discovery and Characterization of SY-1365, a Selective, Covalent Inhibitor of CDK7
Hu, Shanhu, Marineau, Jason J, Rajagopal, Nisha, Hamman, Kristin B, Choi, Yoon Jong, Schmidt, Darby R, Ke, Nan, Johannessen, Liv, Bradley, Michael J, Orlando, David A, Alnemy, Sydney R, Ren, Yixuan, Ciblat, Stephane, Winter, Dana K, Kabro, Anzhelika, Sprott, Kevin T, Hodgson, J Graeme, Fritz, Christian C, Carulli, John P, di Tomaso, Emmanuelle, Olson, Eric R
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
High-Resolution Root Spatiotemporal Map Reveals Dominant Expression Patterns
Brady, Siobhan M, Orlando, David A, Lee, Ji-Young, Wang, Jean Y, Koch, Jeremy, Dinneny, José R, Mace, Daniel, Ohler, Uwe, Benfey, Philip N
Published in Science (American Association for the Advancement of Science) (02.11.2007)
Published in Science (American Association for the Advancement of Science) (02.11.2007)
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Journal Article
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
Ceol, Craig J., Houvras, Yariv, Jane-Valbuena, Judit, Bilodeau, Steve, Orlando, David A., Battisti, Valentine, Fritsch, Lauriane, Lin, William M., Hollmann, Travis J., Ferré, Fabrizio, Bourque, Caitlin, Burke, Christopher J., Turner, Laura, Uong, Audrey, Johnson, Laura A., Beroukhim, Rameen, Mermel, Craig H., Loda, Massimo, Ait-Si-Ali, Slimane, Garraway, Levi A., Young, Richard A., Zon, Leonard I.
Published in Nature (London) (24.03.2011)
Published in Nature (London) (24.03.2011)
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Journal Article
Global control of cell-cycle transcription by coupled CDK and network oscillators
Haase, Steven B, Wang, Jean Y, Lin, Charles Y, Iversen, Edwin S, Hartemink, Alexander J, Orlando, David A, Bernard, Allister, Socolar, Joshua E. S
Published in Nature (12.06.2008)
Published in Nature (12.06.2008)
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Journal Article
Cyclin-Dependent Kinases Are Regulators and Effectors of Oscillations Driven by a Transcription Factor Network
Simmons Kovacs, Laura A., Mayhew, Michael B., Orlando, David A., Jin, Yuanjie, Li, Qingyun, Huang, Chenchen, Reed, Steven I., Mukherjee, Sayan, Haase, Steven B.
Published in Molecular cell (09.03.2012)
Published in Molecular cell (09.03.2012)
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Journal Article
Protonophore‐ and pH‐insensitive glucose and sucrose accumulation detected by FRET nanosensors in Arabidopsis root tips
Chaudhuri, Bhavna, Hörmann, Friederike, Lalonde, Sylvie, Brady, Siobhan M., Orlando, David A., Benfey, Philip, Frommer, Wolf B.
Published in The Plant journal : for cell and molecular biology (01.12.2008)
Published in The Plant journal : for cell and molecular biology (01.12.2008)
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Journal Article
Manipulating large-scale Arabidopsis microarray expression data: identifying dominant expression patterns and biological process enrichment
Orlando, David A, Brady, Siobhan M, Koch, Jeremy D, Dinneny, José R, Benfey, Philip N
Published in Methods in molecular biology (Clifton, N.J.) (2009)
Published in Methods in molecular biology (Clifton, N.J.) (2009)
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Journal Article
Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist
McKeown, Michael R, Corces, M Ryan, Eaton, Matthew L, Fiore, Chris, Lee, Emily, Lopez, Jeremy T, Chen, Mei Wei, Smith, Darren, Chan, Steven M, Koenig, Julie L, Austgen, Kathryn, Guenther, Matthew G, Orlando, David A, Lovén, Jakob, Fritz, Christian C, Majeti, Ravindra
Published in Cancer discovery (01.10.2017)
Published in Cancer discovery (01.10.2017)
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Journal Article
Detecting separate time scales in genetic expression data
Orlando, David A, Brady, Siobhan M, Fink, Thomas M A, Benfey, Philip N, Ahnert, Sebastian E
Published in BMC genomics (16.06.2010)
Published in BMC genomics (16.06.2010)
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