Search Results - "Original Research article" :: K.UTB vyhledávací portál

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ORIGINAL RESEARCH ARTICLE

by Katsube, Takayuki, Shimizu, Ryosuke, Fukuhara, Takahiro, Kano, Takeshi, Wajima, Toshihiro
Published in Clinical pharmacokinetics (01.11.2019)

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Population Pharmacokinetics of Efsubaglutide Alfa in Healthy Subjects and Subjects with Type 2 Diabetes: PopPK of Efsubaglutide Alfa

by Lou, Yan-Ru, Xu, Yu-Long, Xiong, Yifeng, Deng, Chenhui, Wang, Qinghua
Published in Clinical pharmacokinetics (01.04.2025)

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SHR-1918, A Monoclonal Antibody Against Angiopoietin-Like 3, in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Study: SHR-1918, A Monoclonal Antibody Against Aangiopoietin-Like 3, in Healthy Subjects

by Qin, Ruzhai, Ye, Lika, Duan, Lian, Li, Mingyan, He, Wenkai, Mei, Xiao, Li, Deen, Jin, Rong, Lv, Chao, Zhu, Min, Wang, Shihui, Xie, Zhihong
Published in Clinical pharmacokinetics (01.08.2025)

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Population Pharmacokinetics of Telmisartan in Healthy Subjects and Hypertensive Patients: PopPKs of Telmisartan in Healthy Subjects and Hypertensive Patients

by Jeong, In Hwan, Ryu, Sooyoon, Han, Nayoung, Staatz, Christine E., Baek, In-hwan
Published in Clinical pharmacokinetics (01.02.2025)

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Safety and Pharmacokinetics of Single and Multiple Ascending Doses of the Novel Oral Human GLP-1 Analogue, Oral Semaglutide, in Healthy Subjects and Subjects with Type 2 Diabetes

by Granhall, Charlotte, Donsmark, Morten, Blicher, Thalia M., Golor, Georg, Søndergaard, Flemming L., Thomsen, Mette, Bækdal, Tine A.
Published in Clinical pharmacokinetics (01.06.2019)

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A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects

by Taylor, Lesley, Gidal, Barry, Blakey, Graham, Tayo, Bola, Morrison, Gilmour
Published in CNS drugs (01.11.2018)

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Population Pharmacokinetics of Upadacitinib Using the Immediate-Release and Extended-Release Formulations in Healthy Subjects and Subjects with Rheumatoid Arthritis: Analyses of Phase I–III Clinical Trials

by Klünder, Ben, Mittapalli, Rajendar K., Mohamed, Mohamed-Eslam F., Friedel, Anna, Noertersheuser, Peter, Othman, Ahmed A.
Published in Clinical pharmacokinetics (01.08.2019)

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First-in-Human Study on Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Escalating Doses of HEC88473, a Novel Dual GLP-1 and FGF21 Receptor Agonist in Healthy and Obese Chinese Subjects: First-in-Human Study of Single Escalating Doses of HEC88473

by Zhang, Hong, Li, Qianqian, Chen, Hong, Guo, Lingfeng, Li, Jing, Xie, Can, Yan, Jiangyu, Ding, Yanhua
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01.05.2025)

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Effect of Food on the Pharmacokinetic Characteristics of a Single Oral Dose of D-1553, a Selective Inhibitor of KRASG12C, in Healthy Chinese Subjects: D-1553 Food Effect Study

by Liu, Yue, Gao, Xin, Li, Yang, He, Xuemei, Shi, Zhe, Zhang, Ling, Wang, Yaolin, Shi, Aixin
Published in Clinical drug investigation (01.04.2025)

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Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects

by Dolder, Patrick C., Schmid, Yasmin, Steuer, Andrea E., Kraemer, Thomas, Rentsch, Katharina M., Hammann, Felix, Liechti, Matthias E.
Published in Clinical pharmacokinetics (01.10.2017)

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Pharmacokinetics and Pharmacodynamics of Recombinant Human Angiotensin-Converting Enzyme 2 in Healthy Human Subjects

by Haschke, Manuel, Schuster, Manfred, Poglitsch, Marko, Loibner, Hans, Salzberg, Marc, Bruggisser, Marcel, Penninger, Joseph, Krähenbühl, Stephan
Published in Clinical pharmacokinetics (01.09.2013)

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Pharmacokinetic and Pharmacodynamic Properties of Cemdisiran, an RNAi Therapeutic Targeting Complement Component 5, in Healthy Subjects and Patients with Paroxysmal Nocturnal Hemoglobinuria

by Badri, Prajakta, Jiang, Xuemin, Borodovsky, Anna, Najafian, Nader, Kim, Jae, Clausen, Valerie A., Goel, Varun, Habtemariam, Bahru, Robbie, Gabriel J.
Published in Clinical pharmacokinetics (01.03.2021)

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Safety, Pharmacodynamics, and Pharmacokinetics of P2X3 Receptor Antagonist Eliapixant (BAY 1817080) in Healthy Subjects: Double-Blind Randomized Study

by Friedrich, Christian, Francke, Klaus, Gashaw, Isabella, Scheerans, Christian, Klein, Stefan, Fels, Lueder, Smith, Jaclyn A., Hummel, Thomas, Morice, Alyn
Published in Clinical pharmacokinetics (01.08.2022)

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Population Pharmacokinetics of Esketamine Nasal Spray and its Metabolite Noresketamine in Healthy Subjects and Patients with Treatment-Resistant Depression

by Perez-Ruixo, Carlos, Rossenu, Stefaan, Zannikos, Peter, Nandy, Partha, Singh, Jaskaran, Drevets, Wayne C., Perez-Ruixo, Juan Jose
Published in Clinical pharmacokinetics (01.04.2021)

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Bioequivalence and Safety of Two Amisulpride Formulations in Healthy Chinese Subjects Under Fasting and Fed Conditions: A Randomized, Open‑Label, Single‑Dose, Crossover Study: Bioequivalence and Safety of Two Amisulpride Formulations

by Wang, Min, Peng, Yu, Yan, Hegui, Pan, Zhixiang, Du, Ronghui, Liu, Guan
Published in Drugs in R&D (01.06.2025)

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Pharmacokinetics, Pharmacodynamics, and Safety of Single Dose HSK7653 Tablets in Chinese Subjects with Normal or Impaired Renal Function

by Shi, Dan, Chen, Lin, Li, Gexuan, Wu, Nan, Zhang, Fengyi, Wang, Xiaofei, Mu, Nan, Chen, Xi, Yang, Xiangyi, Lu, Jia, Lu, Yali, Wang, Meixia, Zhang, Dongliang
Published in Clinical pharmacokinetics (01.02.2024)

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Population Pharmacokinetics of Upadacitinib in Healthy Subjects and Subjects with Rheumatoid Arthritis: Analyses of Phase I and II Clinical Trials

by Klünder, Ben, Mohamed, Mohamed-Eslam F., Othman, Ahmed A.
Published in Clinical pharmacokinetics (01.08.2018)

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Bioequivalence Analysis of Ondansetron Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Two-Period Crossover Phase I Study: Bioequivalence Analysis of Ondansetron Hydrochloride Tablets

by Jia, Caiyun, Zhao, Na, Song, Haojing, Hu, Yiting, Xu, Yufang, Guo, Caihui, Bai, Wanjun, Dong, Zhanjun
Published in Drugs in R&D (01.12.2024)

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Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects with Renal Impairment

by Granhall, Charlotte, Søndergaard, Flemming L., Thomsen, Mette, Anderson, Thomas W.
Published in Clinical pharmacokinetics (01.12.2018)

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A Phase I, Open-Label, Parallel-Group, Single-Dose Trial of the Pharmacokinetics, Safety, and Tolerability of Cannabidiol in Subjects with Mild to Severe Renal Impairment

by Tayo, Bola, Taylor, Lesley, Sahebkar, Farhad, Morrison, Gilmour
Published in Clinical pharmacokinetics (01.06.2020)

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