IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation
Allinne, Jeanne, Scott, George, Lim, Wei Keat, Birchard, Dylan, Erjefält, Jonas S., Sandén, Caroline, Ben, Li-Hong, Agrawal, Amit, Kaur, Navneet, Kim, Jee Hae, Kamat, Vishal, Fury, Wen, Huang, Tammy, Stahl, Neil, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Matthew A., Orengo, Jamie M.
Published in Journal of allergy and clinical immunology (01.12.2019)
Published in Journal of allergy and clinical immunology (01.12.2019)
Get full text
Journal Article
Biologics as novel therapeutics for the treatment of allergy: Challenges and opportunities
Atanasio, Amanda, Orengo, Jamie M., Sleeman, Matthew A., Stahl, Neil
Published in Frontiers in allergy (24.10.2022)
Published in Frontiers in allergy (24.10.2022)
Get full text
Journal Article
Chronic allergen exposure drives accumulation of long-lived IgE plasma cells in the bone marrow, giving rise to serological memory
Asrat, Seblewongel, Kaur, Navneet, Liu, Xia, Ben, Li-Hong, Kajimura, Daisuke, Murphy, Andrew J, Sleeman, Matthew A, Limnander, Andre, Orengo, Jamie M
Published in Science immunology (10.01.2020)
Published in Science immunology (10.01.2020)
Get more information
Journal Article
REGN1908‐1909 monoclonal antibodies block Fel d 1 in cat allergic subjects: Translational pharmacokinetics and pharmacodynamics
Kamal, Mohamed A., Dingman, Robert, Wang, Claire Q., Lai, Ching‐Ha, Rajadhyaksha, Manoj, DeVeaux, Michelle, Orengo, Jamie M., Radin, Allen, Davis, John D.
Published in Clinical and translational science (01.11.2021)
Published in Clinical and translational science (01.11.2021)
Get full text
Journal Article
Dual blockade of IL‐4 and IL‐13 with dupilumab, an IL‐4Rα antibody, is required to broadly inhibit type 2 inflammation
Le Floc’h, Audrey, Allinne, Jeanne, Nagashima, Kirsten, Scott, George, Birchard, Dylan, Asrat, Seblewongel, Bai, Yu, Lim, Wei Keat, Martin, Joel, Huang, Tammy, Potocky, Terra B., Kim, Jee H., Rafique, Ashique, Papadopoulos, Nicholas J., Stahl, Neil, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Matthew A., Orengo, Jamie M.
Published in Allergy (Copenhagen) (01.05.2020)
Published in Allergy (Copenhagen) (01.05.2020)
Get full text
Journal Article
Plasmodium-induced inflammation by uric acid
Orengo, Jamie M, Evans, James E, Bettiol, Esther, Leliwa-Sytek, Aleksandra, Day, Karen, Rodriguez, Ana
Published in PLoS pathogens (07.03.2008)
Published in PLoS pathogens (07.03.2008)
Get full text
Journal Article
Passive Prophylactic Administration with a Single Dose of Anti–Fel d 1 Monoclonal Antibodies REGN1908–1909 in Cat Allergen–induced Allergic Rhinitis: A Randomized, Double-Blind, Placebo-controlled Clinical Trial
Shamji, Mohamed H., Singh, Iesha, Layhadi, Janice A., Ito, Constance, Karamani, Angeliki, Kouser, Lubna, Sharif, Hanisah, Tang, Jiaqian, Handijiev, Sava, Parkin, Rebecca V., Durham, Stephen R., Kostic, Ana, Orengo, Jamie M., DeVeaux, Michelle, Kamal, Mohamed, Stahl, Neil, Yancopoulos, George D., Wang, Claire Q., Radin, Allen R.
Published in American journal of respiratory and critical care medicine (01.07.2021)
Published in American journal of respiratory and critical care medicine (01.07.2021)
Get full text
Journal Article
Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response
Atanasio, Amanda, Franklin, Matthew C., Kamat, Vishal, Hernandez, Annabel Romero, Badithe, Ashok, Ben, Li-Hong, Jones, Jennifer, Bautista, Joannie, Yancopoulos, George D., Olson, William, Murphy, Andrew J., Sleeman, Matthew A., Orengo, Jamie M.
Published in Journal of allergy and clinical immunology (01.01.2022)
Published in Journal of allergy and clinical immunology (01.01.2022)
Get full text
Journal Article
IL-4 and IL-13, not eosinophils, drive type 2 airway inflammation, remodeling and lung function decline
Scott, George, Asrat, Seblewongel, Allinne, Jeanne, Keat Lim, Wei, Nagashima, Kirsten, Birchard, Dylan, Srivatsan, Subhashini, Ajithdoss, Dharani K., Oyejide, Adelekan, Ben, Li-Hong, Walls, Johnathon, Le Floc'h, Audrey, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Matthew A., Orengo, Jamie M.
Published in Cytokine (Philadelphia, Pa.) (01.02.2023)
Published in Cytokine (Philadelphia, Pa.) (01.02.2023)
Get full text
Journal Article
Novel antibody cocktail targeting Bet v 1 rapidly and sustainably treats birch allergy symptoms in a phase 1 study
Gevaert, Philippe, De Craemer, Jarno, De Ruyck, Natalie, Rottey, Sylvie, de Hoon, Jan, Hellings, Peter W., Volckaert, Bram, Lesneuck, Kristof, Orengo, Jamie M., Atanasio, Amanda, Kamal, Mohamed A., Abdallah, Hisham, Kamat, Vishal, Dingman, Robert, DeVeaux, Michelle, Ramesh, Divya, Perlee, Lorah, Wang, Claire Q., Weinreich, David M., Herman, Gary, Yancopoulos, George D., O’Brien, Meagan P.
Published in Journal of allergy and clinical immunology (01.01.2022)
Published in Journal of allergy and clinical immunology (01.01.2022)
Get full text
Journal Article
REGN1908/1909 prevented cat allergen–induced early asthmatic responses in an environmental exposure unit
de Blay, Frederic J., Gherasim, Alina, Domis, Nathalie, Meier, Pretty, Shawki, Furat, Wang, Claire Q., Orengo, Jamie M., DeVeaux, Michelle, Ramesh, Divya, Jalbert, Jessica J., Kamal, Mohamed A., Abdallah, Hisham, Dingman, Robert, Perlee, Lorah, Weinreich, David.M., Herman, Gary, Yancopoulos, George D., O’Brien, Meagan P.
Published in Journal of allergy and clinical immunology (01.12.2022)
Published in Journal of allergy and clinical immunology (01.12.2022)
Get full text
Journal Article
The IL-4-IL-4Rα axis modulates olfactory neuroimmune signaling to induce loss of smell
Hara, Yannis, Jha, Mithilesh Kumar, Huang, Jeremy Y, Han, Yingnan, Langohr, Ingeborg M, Gaglia, Giorgio, Zhu, Cheng, Piepenhagen, Peter, Gayvert, Kaitlyn, Lim, Wei Keat, Asrat, Seblewongel, Nash, Scott, Jacob-Nara, Juby A, Orengo, Jamie M, Bangari, Dinesh S, de Rinaldis, Emanuele, Mattoo, Hamid, Hicks, Alexandra
Published in Allergy (Copenhagen) (17.10.2024)
Published in Allergy (Copenhagen) (17.10.2024)
Get full text
Journal Article
Differential modulation of allergic rhinitis nasal transcriptome by dupilumab and allergy immunotherapy
Wipperman, Matthew F., Gayvert, Kaitlyn M., Atanasio, Amanda, Wang, Claire Q., Corren, Jonathan, Covarrubias, Angelica, Setliff, Ian, Chio, Erica, Laws, Elizabeth, Wolfe, Kelley, Harel, Sivan, Maloney, Jennifer, Herman, Gary, Orengo, Jamie M., Lim, Wei Keat, Hamon, Sara C., Hamilton, Jennifer D., O'Brien, Meagan P.
Published in Allergy (Copenhagen) (01.04.2024)
Published in Allergy (Copenhagen) (01.04.2024)
Get full text
Journal Article
A therapeutic strategy to target distinct sources of IgE and durably reverse allergy
Limnander, Andre, Kaur, Navneet, Asrat, Seblewongel, Tasker, Carley, Boyapati, Anita, Ben, Li-Hong, Janczy, John, Pedraza, Paulina, Abreu, Pablo, Chen, Wen-Chi, Godin, Stephen, Daniel, Benjamin J, Chin, Harvey, DeVeaux, Michelle, Rodriguez Lorenc, Karen, Sirulnik, Andres, Harari, Olivier, Stahl, Neil, Sleeman, Matthew A, Murphy, Andrew J, Yancopoulos, George D, Orengo, Jamie M
Published in Science translational medicine (13.12.2023)
Published in Science translational medicine (13.12.2023)
Get more information
Journal Article
Pathophysiology of Bullous Pemphigoid: Role of Type 2 Inflammation and Emerging Treatment Strategies (Narrative Review)
Werth, Victoria P., Murrell, Dédée F., Joly, Pascal, Heck, Renata, Orengo, Jamie M., Ardeleanu, Marius, Hultsch, Verena
Published in Advances in therapy (01.12.2024)
Published in Advances in therapy (01.12.2024)
Get full text
Journal Article
A Plasmodium yoelii soluble factor inhibits the phenotypic maturation of dendritic cells
Orengo, Jamie M, Wong, Kurt A, Ocaña-Morgner, Carlos, Rodriguez, Ana
Published in Malaria journal (15.12.2008)
Published in Malaria journal (15.12.2008)
Get full text
Journal Article
Clinical and immunological evaluation of cat‐allergic asthmatics living with or without a cat
Wambre, Erik R., Farrington, Mary, Bajzik, Veronique, DeBerg, Hannah A., Ruddy, Marcella, DeVeaux, Michelle, Meier, Pretty, Robinson, David, Cantor, Matt, Huang, Chengrui, Orengo, Jamie M., Wang, Claire Q., Radin, Allen
Published in Clinical and experimental allergy (01.12.2021)
Published in Clinical and experimental allergy (01.12.2021)
Get full text
Journal Article
Blocking common γ chain cytokine signaling ameliorates T cell-mediated pathogenesis in disease models
Le Floc'h, Audrey, Nagashima, Kirsten, Birchard, Dylan, Scott, George, Ben, Li-Hong, Ajithdoss, Dharani, Gayvert, Kaitlyn, Romero Hernandez, Annabel, Herbin, Olivier, Tay, Amanda, Farrales, Pamela, Korgaonkar, Chandrashekhar K, Pan, Hao, Shah, Sweta, Kamat, Vishal, Chatterjee, Ishita, Popke, Jon, Oyejide, Adelekan, Lim, Wei Keat, Kim, Jee H, Huang, Tammy, Franklin, Matthew, Olson, William, Norton, Thomas, Perlee, Lorah, Yancopoulos, George D, Murphy, Andrew J, Sleeman, Matthew A, Orengo, Jamie M
Published in Science translational medicine (11.01.2023)
Published in Science translational medicine (11.01.2023)
Get more information
Journal Article
Dupilumab Significantly Modulates Pain and Discomfort in Patients With Atopic Dermatitis: A Post Hoc Analysis of 5 Randomized Clinical Trials
Silverberg, Jonathan I, Simpson, Eric L, Guttman-Yassky, Emma, Cork, Michael J, de Bruin-Weller, Marjolein, Yosipovitch, Gil, Eckert, Laurent, Chen, Zhen, Ardeleanu, Marius, Shumel, Brad, Hultsch, Thomas, Rossi, Ana B, Hamilton, Jennifer D, Orengo, Jamie M, Ruddy, Marcella, Graham, Neil M H, Pirozzi, Gianluca, Gadkari, Abhijit
Published in Dermatitis (01.10.2021)
Published in Dermatitis (01.10.2021)
Get more information
Journal Article
TRAPnSeq allows high-throughput profiling of antigen-specific antibody-secreting cells
Asrat, Seblewongel, Devlin, Joseph C., Vecchione, Andrea, Klotz, Brian, Setliff, Ian, Srivastava, Devin, Limnander, Andre, Rafique, Ashique, Adler, Christina, Porter, Stephen, Murphy, Andrew J., Atwal, Gurinder S., Sleeman, Matthew A., Lim, Wei Keat, Orengo, Jamie M.
Published in Cell reports methods (24.07.2023)
Published in Cell reports methods (24.07.2023)
Get full text
Journal Article