RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares
Orange, Dana E, Yao, Vicky, Sawicka, Kirsty, Fak, John, Frank, Mayu O, Parveen, Salina, Blachere, Nathalie E, Hale, Caryn, Zhang, Fan, Raychaudhuri, Soumya, Troyanskaya, Olga G, Darnell, Robert B
Published in The New England journal of medicine (16.07.2020)
Published in The New England journal of medicine (16.07.2020)
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Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation
Stephenson, William, Donlin, Laura T., Butler, Andrew, Rozo, Cristina, Bracken, Bernadette, Rashidfarrokhi, Ali, Goodman, Susan M., Ivashkiv, Lionel B., Bykerk, Vivian P., Orange, Dana E., Darnell, Robert B., Swerdlow, Harold P., Satija, Rahul
Published in Nature communications (23.02.2018)
Published in Nature communications (23.02.2018)
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Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data
Orange, Dana E., Agius, Phaedra, DiCarlo, Edward F., Robine, Nicolas, Geiger, Heather, Szymonifka, Jackie, McNamara, Michael, Cummings, Ryan, Andersen, Kathleen M., Mirza, Serene, Figgie, Mark, Ivashkiv, Lionel B., Pernis, Alessandra B., Jiang, Caroline S., Frank, Mayu O., Darnell, Robert B., Lingampali, Nithya, Robinson, William H., Gravallese, Ellen, Bykerk, Vivian P., Goodman, Susan M., Donlin, Laura T.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2018)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2018)
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Machine learning identification of thresholds to discriminate osteoarthritis and rheumatoid arthritis synovial inflammation
Mehta, Bella, Goodman, Susan, DiCarlo, Edward, Jannat-Khah, Deanna, Gibbons, J Alex B, Otero, Miguel, Donlin, Laura, Pannellini, Tania, Robinson, William H, Sculco, Peter, Figgie, Mark, Rodriguez, Jose, Kirschmann, Jessica M, Thompson, James, Slater, David, Frezza, Damon, Xu, Zhenxing, Wang, Fei, Orange, Dana E
Published in Arthritis research & therapy (02.03.2023)
Published in Arthritis research & therapy (02.03.2023)
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Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression
Meednu, Nida, Rangel-Moreno, Javier, Zhang, Fan, Escalera-Rivera, Katherine, Corsiero, Elisa, Prediletto, Edoardo, DiCarlo, Edward, Goodman, Susan, Donlin, Laura T., Raychauduri, Soumya, Bombardieri, Michele, Pitzalis, Costantino, Orange, Dana E., McDavid, Andrew, Anolik, Jennifer H.
Published in Cell reports (Cambridge) (03.05.2022)
Published in Cell reports (Cambridge) (03.05.2022)
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Rheumatoid Arthritis Flares After Total Hip and Total Knee Arthroplasty: Outcomes at One Year
Goodman, Susan M., Mirza, Serene Z., DiCarlo, Edward F., Pearce‐Fisher, Diyu, Zhang, Meng, Mehta, Bella, Donlin, Laura T., Bykerk, Vivian P., Figgie, Mark P., Orange, Dana E.
Published in Arthritis care & research (2010) (01.07.2020)
Published in Arthritis care & research (2010) (01.07.2020)
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Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue
Bell, Richard D., Brendel, Matthew, Konnaris, Maxwell A., Xiang, Justin, Otero, Miguel, Fontana, Mark A., Bai, Zilong, Krenitsky, Daria M., Meednu, Nida, Rangel-Moreno, Javier, Scheel-Toellner, Dagmar, Carr, Hayley, Nayar, Saba, McMurray, Jack, DiCarlo, Edward, Anolik, Jennifer H., Donlin, Laura T., Orange, Dana E., Kenney, H. Mark, Schwarz, Edward M., Filer, Andrew, Ivashkiv, Lionel B., Wang, Fei
Published in Nature communications (29.08.2024)
Published in Nature communications (29.08.2024)
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Rheumatoid Arthritis Synovial Inflammation Quantification Using Computer Vision
Guan, Steven, Mehta, Bella, Slater, David, Thompson, James R., DiCarlo, Edward, Pannellini, Tania, Pearce‐Fisher, Diyu, Zhang, Fan, Raychaudhuri, Soumya, Hale, Caryn, Jiang, Caroline S., Goodman, Susan, Orange, Dana E.
Published in ACR open rheumatology (01.04.2022)
Published in ACR open rheumatology (01.04.2022)
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Sequencing and curation strategies for identifying candidate glioblastoma treatments
Frank, Mayu O, Koyama, Takahiko, Rhrissorrakrai, Kahn, Robine, Nicolas, Utro, Filippo, Emde, Anne-Katrin, Chen, Bo-Juen, Arora, Kanika, Shah, Minita, Geiger, Heather, Felice, Vanessa, Dikoglu, Esra, Rahman, Sadia, Fang, Alice, Vacic, Vladimir, Bergmann, Ewa A, Vogel, Julia L Moore, Reeves, Catherine, Khaira, Depinder, Calabro, Anthony, Kim, Duyang, Lamendola-Essel, Michelle F, Esteves, Cecilia, Agius, Phaedra, Stolte, Christian, Boockvar, John, Demopoulos, Alexis, Placantonakis, Dimitris G, Golfinos, John G, Brennan, Cameron, Bruce, Jeffrey, Lassman, Andrew B, Canoll, Peter, Grommes, Christian, Daras, Mariza, Diamond, Eli, Omuro, Antonio, Pentsova, Elena, Orange, Dana E, Harvey, Stephen J, Posner, Jerome B, Michelini, Vanessa V, Jobanputra, Vaidehi, Zody, Michael C, Kelly, John, Parida, Laxmi, Wrzeszczynski, Kazimierz O, Royyuru, Ajay K, Darnell, Robert B
Published in BMC medical genomics (25.04.2019)
Published in BMC medical genomics (25.04.2019)
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Correction to: Sequencing and curation strategies for identifying candidate glioblastoma treatments
Frank, Mayu O, Koyama, Takahiko, Rhrissorrakrai, Kahn, Robine, Nicolas, Utro, Filippo, Emde, Anne-Katrin, Chen, Bo-Juen, Arora, Kanika, Shah, Minita, Geiger, Heather, Felice, Vanessa, Dikoglu, Esra, Rahman, Sadia, Fang, Xiaolan, Vacic, Vladimir, Bergmann, Ewa A, Moore Vogel, Julia L, Reeves, Catherine, Khaira, Depinder, Calabro, Anthony, Kim, Duyang, Lamendola-Essel, Michelle F, Esteves, Cecilia, Agius, Phaedra, Stolte, Christian, Boockvar, John, Demopoulos, Alexis, Placantonakis, Dimitris G, Golfinos, John G, Brennan, Cameron, Bruce, Jeffrey, Lassman, Andrew B, Canoll, Peter, Grommes, Christian, Daras, Mariza, Diamond, Eli, Omuro, Antonio, Pentsova, Elena, Orange, Dana E, Harvey, Stephen J, Posner, Jerome B, Michelini, Vanessa V, Jobanputra, Vaidehi, Zody, Michael C, Kelly, John, Parida, Laxmi, Wrzeszczynski, Kazimierz O, Royyuru, Ajay K, Darnell, Robert B
Published in BMC medical genomics (02.08.2019)
Published in BMC medical genomics (02.08.2019)
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Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
Zhang, Fan, Wei, Kevin, Slowikowski, Kamil, Fonseka, Chamith Y., Rao, Deepak A., Kelly, Stephen, Goodman, Susan M., Tabechian, Darren, Hughes, Laura B., Salomon-Escoto, Karen, Watts, Gerald F. M., Jonsson, A. Helena, Rangel-Moreno, Javier, Meednu, Nida, Rozo, Cristina, Apruzzese, William, Eisenhaure, Thomas M., Lieb, David J., Boyle, David L., Mandelin, Arthur M., Boyce, Brendan F., DiCarlo, Edward, Gravallese, Ellen M., Gregersen, Peter K., Moreland, Larry, Firestein, Gary S., Hacohen, Nir, Nusbaum, Chad, Lederer, James A., Perlman, Harris, Pitzalis, Costantino, Filer, Andrew, Holers, V. Michael, Bykerk, Vivian P., Donlin, Laura T., Anolik, Jennifer H., Brenner, Michael B., Raychaudhuri, Soumya
Published in Nature immunology (01.07.2019)
Published in Nature immunology (01.07.2019)
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Dendritic cells loaded with FK506 kill T cells in an antigen-specific manner and prevent autoimmunity in vivo
Orange, Dana E, Blachere, Nathalie E, Fak, John, Parveen, Salina, Frank, Mayu O, Herre, Margo, Tian, Suyan, Monette, Sebastien, Darnell, Robert B
Published in eLife (05.02.2013)
Published in eLife (05.02.2013)
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Notch signalling drives synovial fibroblast identity and arthritis pathology
Wei, Kevin, Korsunsky, Ilya, Marshall, Jennifer L., Gao, Anqi, Watts, Gerald F. M., Major, Triin, Croft, Adam P., Watts, Jordan, Blazar, Philip E., Lange, Jeffrey K., Thornhill, Thomas S., Filer, Andrew, Raza, Karim, Donlin, Laura T., Siebel, Christian W., Buckley, Christopher D., Raychaudhuri, Soumya, Brenner, Michael B.
Published in Nature (London) (01.06.2020)
Published in Nature (London) (01.06.2020)
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Response to: ‘Correspondence on ‘Machine learning integration of scleroderma histology and gene expression identifies fibroblast polarisation as a hallmark of clinical severity and improvement’’ by Manetti
Showalter, Kimberly, Magro, Cynthia, Zhang, Yaxia, Spiera, Robert, Orange, Dana E, Gordon, Jessica K
Published in Annals of the rheumatic diseases (01.01.2023)
Published in Annals of the rheumatic diseases (01.01.2023)
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Journal Article
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes
Zhang, Fan, Jonsson, Anna Helena, Nathan, Aparna, Millard, Nghia, Curtis, Michelle, Xiao, Qian, Gutierrez-Arcelus, Maria, Apruzzese, William, Watts, Gerald F. M., Weisenfeld, Dana, Nayar, Saba, Rangel-Moreno, Javier, Meednu, Nida, Marks, Kathryne E., Mantel, Ian, Kang, Joyce B., Rumker, Laurie, Mears, Joseph, Slowikowski, Kamil, Weinand, Kathryn, Orange, Dana E., Geraldino-Pardilla, Laura, Deane, Kevin D., Tabechian, Darren, Ceponis, Arnoldas, Firestein, Gary S., Maybury, Mark, Sahbudin, Ilfita, Ben-Artzi, Ami, Mandelin, Arthur M., Nerviani, Alessandra, Lewis, Myles J., Rivellese, Felice, Pitzalis, Costantino, Hughes, Laura B., Horowitz, Diane, DiCarlo, Edward, Gravallese, Ellen M., Boyce, Brendan F., Moreland, Larry W., Goodman, Susan M., Perlman, Harris, Holers, V. Michael, Liao, Katherine P., Filer, Andrew, Bykerk, Vivian P., Wei, Kevin, Rao, Deepak A., Donlin, Laura T., Anolik, Jennifer H., Brenner, Michael B., Raychaudhuri, Soumya
Published in Nature (London) (16.11.2023)
Published in Nature (London) (16.11.2023)
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Advancing Rheumatoid Arthritis Synovial Biopsy Analysis: One B Cell at a Time
Orange, Dana E., Donlin, Laura T.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2020)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2020)
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Computer Vision Analysis of Rheumatoid Arthritis Synovium Reveals Lymphocytic Inflammation Is Associated With Immunoglobulin Skewing in Blood
Frezza, Damon, DiCarlo, Edward, Hale, Caryn, Ramirez, Daniel, Mehta, Bella, Slater, David, Habib, Saimun, Frank, Mayu O., Spolaore, Edoardo, Smith, Melanie H., Donlin, Laura, Goodman, Susan, Thompson, James R., Orange, Dana E.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2023)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2023)
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Rheumatoid Arthritis Morning Stiffness Is Associated With Synovial Fibrin and Neutrophils
Orange, Dana E., Blachere, Nathalie E., DiCarlo, Edward F., Mirza, Serene, Pannellini, Tania, Jiang, Caroline S., Frank, Mayu O., Parveen, Salina, Figgie, Mark P., Gravallese, Ellen M., Bykerk, Vivian P., Orbai, Ana‐Maria, Mackie, Sarah L., Goodman, Susan M.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2020)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2020)
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