100 years of insulin: celebrating the past, present and future of diabetes therapy
Sims, Emily K., Carr, Alice L. J., Oram, Richard A., DiMeglio, Linda A., Evans-Molina, Carmella
Published in Nature medicine (01.07.2021)
Published in Nature medicine (01.07.2021)
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Journal Article
A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults
Oram, Richard A, Patel, Kashyap, Hill, Anita, Shields, Beverley, McDonald, Timothy J, Jones, Angus, Hattersley, Andrew T, Weedon, Michael N
Published in Diabetes care (01.03.2016)
Published in Diabetes care (01.03.2016)
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Journal Article
Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis
Sharp, Seth A, Rich, Stephen S, Wood, Andrew R, Jones, Samuel E, Beaumont, Robin N, Harrison, James W, Schneider, Darius A, Locke, Jonathan M, Tyrrell, Jess, Weedon, Michael N, Hagopian, William A, Oram, Richard A
Published in Diabetes care (01.02.2019)
Published in Diabetes care (01.02.2019)
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Journal Article
Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank
Thomas, Nicholas J, Jones, Samuel E, Weedon, Michael N, Shields, Beverley M, Oram, Richard A, Hattersley, Andrew T
Published in The lancet. Diabetes & endocrinology (01.02.2018)
Published in The lancet. Diabetes & endocrinology (01.02.2018)
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Journal Article
Preventing type 1 diabetes in childhood
Dayan, Colin M., Besser, Rachel E. J., Oram, Richard A., Hagopian, William, Vatish, Manu, Bendor-Samuel, Owen, Snape, Matthew D., Todd, John A.
Published in Science (American Association for the Advancement of Science) (30.07.2021)
Published in Science (American Association for the Advancement of Science) (30.07.2021)
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Journal Article
Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes
Patel, K A, Oram, R A, Flanagan, S E, De Franco, E, Colclough, K, Shepherd, M, Ellard, S, Weedon, M N, Hattersley, A T
Published in Diabetes (New York, N.Y.) (01.07.2016)
Published in Diabetes (New York, N.Y.) (01.07.2016)
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Journal Article
Utility of genetic risk scores in type 1 diabetes
Luckett, Amber M., Weedon, Michael N., Hawkes, Gareth, Leslie, R. David, Oram, Richard A., Grant, Struan F. A.
Published in Diabetologia (01.09.2023)
Published in Diabetologia (01.09.2023)
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Journal Article
Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children
Bonifacio, Ezio, Beyerlein, Andreas, Hippich, Markus, Winkler, Christiane, Vehik, Kendra, Weedon, Michael N, Laimighofer, Michael, Hattersley, Andrew T, Krumsiek, Jan, Frohnert, Brigitte I, Steck, Andrea K, Hagopian, William A, Krischer, Jeffrey P, Lernmark, Åke, Rewers, Marian J, She, Jin-Xiong, Toppari, Jorma, Akolkar, Beena, Oram, Richard A, Rich, Stephen S, Ziegler, Anette-G
Published in PLoS medicine (03.04.2018)
Published in PLoS medicine (03.04.2018)
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Journal Article
Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis
Loginovic, Pavel, Wang, Feiyi, Li, Jiang, Ferrat, Lauric, Mirshahi, Uyenlinh L., Rao, H. Shanker, Petzold, Axel, Tyrrell, Jessica, Green, Harry D., Weedon, Michael N., Ganna, Andrea, Tuomi, Tiinamaija, Carey, David J., Oram, Richard A., Braithwaite, Tasanee
Published in Nature communications (28.02.2024)
Published in Nature communications (28.02.2024)
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Journal Article
A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care
Sharp, Seth A., Jones, Samuel E., Kimmitt, Robert A., Weedon, Michael N., Halpin, Anne M., Wood, Andrew R., Beaumont, Robin N., King, Seema, Heel, David A., Campbell, Patricia M., Hagopian, William A., Turner, Justine M., Oram, Richard A
Published in Alimentary pharmacology & therapeutics (01.10.2020)
Published in Alimentary pharmacology & therapeutics (01.10.2020)
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Journal Article
Type 1 diabetes
DiMeglio, Linda A, Evans-Molina, Carmella, Oram, Richard A
Published in The Lancet (British edition) (16.06.2018)
Published in The Lancet (British edition) (16.06.2018)
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Journal Article
Estimating disease prevalence in large datasets using genetic risk scores
Evans, Benjamin D., Słowiński, Piotr, Hattersley, Andrew T., Jones, Samuel E., Sharp, Seth, Kimmitt, Robert A., Weedon, Michael N., Oram, Richard A., Tsaneva-Atanasova, Krasimira, Thomas, Nicholas J.
Published in Nature communications (08.11.2021)
Published in Nature communications (08.11.2021)
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Journal Article
Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes
Ocaña, Gail J, Sims, Emily K, Watkins, Renecia A, Ragg, Susanne, Mather, Kieren J, Oram, Richard A, Mirmira, Raghavendra G, DiMeglio, Linda A, Blum, Janice S, Evans-Molina, Carmella
Published in PloS one (01.01.2019)
Published in PloS one (01.01.2019)
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Journal Article
IgA Nephropathy Genetic Risk Score to Estimate the Prevalence of IgA Nephropathy in UK Biobank
Sukcharoen, Kittiya, Sharp, Seth A., Thomas, Nicholas J., Kimmitt, Robert A., Harrison, Jamie, Bingham, Coralie, Mozere, Monika, Weedon, Michael N., Tyrrell, Jessica, Barratt, Jonathan, Gale, Daniel P., Oram, Richard A.
Published in Kidney international reports (01.10.2020)
Published in Kidney international reports (01.10.2020)
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Journal Article
Teplizumab approval for type 1 diabetes in the USA
Evans-Molina, Carmella, Oram, Richard A.
Published in The lancet. Diabetes & endocrinology (01.02.2023)
Published in The lancet. Diabetes & endocrinology (01.02.2023)
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Journal Article
Mutations in the hepatocyte nuclear factor-1β ( HNF1B) gene are common with combined uterine and renal malformations but are not found with isolated uterine malformations
Oram, Richard A., MD, Edghill, Emma L., PhD, Blackman, Jenny, MD, Taylor, Miles J.O., MD, Kay, Tracey, MD, Flanagan, Sarah E., PhD, Ismail-Pratt, Ida, MD, Creighton, Sarah M., MD, Ellard, Sian, PhD, Hattersley, Andrew T., DM, Bingham, Coralie, MD
Published in American journal of obstetrics and gynecology (01.10.2010)
Published in American journal of obstetrics and gynecology (01.10.2010)
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Journal Article
Logistic regression has similar performance to optimised machine learning algorithms in a clinical setting: application to the discrimination between type 1 and type 2 diabetes in young adults
Lynam, Anita L, Dennis, John M, Owen, Katharine R, Oram, Richard A, Jones, Angus G, Shields, Beverley M, Ferrat, Lauric A
Published in Diagnostic and prognostic research (04.06.2020)
Published in Diagnostic and prognostic research (04.06.2020)
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