Interplay between metabolic identities in the intestinal crypt supports stem cell function
Rodríguez-Colman, Maria J., Schewe, Matthias, Meerlo, Maaike, Stigter, Edwin, Gerrits, Johan, Pras-Raves, Mia, Sacchetti, Andrea, Hornsveld, Marten, Oost, Koen C., Snippert, Hugo J., Verhoeven-Duif, Nanda, Fodde, Riccardo, Burgering, Boudewijn M. T.
Published in Nature (London) (16.03.2017)
Published in Nature (London) (16.03.2017)
Get full text
Journal Article
High-resolution 3D imaging of fixed and cleared organoids
Dekkers, Johanna F., Alieva, Maria, Wellens, Lianne M., Ariese, Hendrikus C. R., Jamieson, Paul R., Vonk, Annelotte M., Amatngalim, Gimano D., Hu, Huili, Oost, Koen C., Snippert, Hugo J. G., Beekman, Jeffrey M., Wehrens, Ellen J., Visvader, Jane E., Clevers, Hans, Rios, Anne C.
Published in Nature protocols (01.06.2019)
Published in Nature protocols (01.06.2019)
Get full text
Journal Article
Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer
Fumagalli, Arianna, Oost, Koen C., Kester, Lennart, Morgner, Jessica, Bornes, Laura, Bruens, Lotte, Spaargaren, Lisa, Azkanaz, Maria, Schelfhorst, Tim, Beerling, Evelyne, Heinz, Maria C., Postrach, Daniel, Seinstra, Danielle, Sieuwerts, Anieta M., Martens, John W.M., van der Elst, Stefan, van Baalen, Martijn, Bhowmick, Debajit, Vrisekoop, Nienke, Ellenbroek, Saskia I.J., Suijkerbuijk, Saskia J.E., Snippert, Hugo J., van Rheenen, Jacco
Published in Cell stem cell (02.04.2020)
Published in Cell stem cell (02.04.2020)
Get full text
Journal Article
A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression
Fumagalli, Arianna, Suijkerbuijk, Saskia J E, Begthel, Harry, Beerling, Evelyne, Oost, Koen C, Snippert, Hugo J, van Rheenen, Jacco, Drost, Jarno
Published in Nature protocols (01.02.2018)
Published in Nature protocols (01.02.2018)
Get full text
Journal Article
Integrative multi‐omics analysis of intestinal organoid differentiation
Lindeboom, Rik GH, van Voorthuijsen, Lisa, Oost, Koen C, Rodríguez‐Colman, Maria J, Luna‐Velez, Maria V, Furlan, Cristina, Baraille, Floriane, Jansen, Pascal WTC, Ribeiro, Agnès, Burgering, Boudewijn MT, Snippert, Hugo J, Vermeulen, Michiel
Published in Molecular systems biology (01.06.2018)
Published in Molecular systems biology (01.06.2018)
Get full text
Journal Article
Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene
Oost, Koen C., van Voorthuijsen, Lisa, Fumagalli, Arianna, Lindeboom, Rik G.H., Sprangers, Joep, Omerzu, Manja, Rodriguez-Colman, Maria J., Heinz, Maria C., Verlaan-Klink, Ingrid, Maurice, Madelon M., Burgering, Boudewijn M.T., van Rheenen, Jacco, Vermeulen, Michiel, Snippert, Hugo J.G.
Published in Cell reports (Cambridge) (06.02.2018)
Published in Cell reports (Cambridge) (06.02.2018)
Get full text
Journal Article
Advances in optical pooled screening to map spatial complexity
Kahnwald, Maurice, Mählen, Marius, Oost, Koen C, Liberali, Prisca
Published in Nature biotechnology (07.10.2024)
Published in Nature biotechnology (07.10.2024)
Get full text
Journal Article
Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage
Heinz, Maria C, Peters, Niek A, Oost, Koen C, Lindeboom, Rik G H, van Voorthuijsen, Lisa, Fumagalli, Arianna, van der Net, Mirjam C, de Medeiros, Gustavo, Hageman, Joris H, Verlaan-Klink, Ingrid, Borel Rinkes, Inne H M, Liberali, Prisca, Gloerich, Martijn, van Rheenen, Jacco, Vermeulen, Michiel, Kranenburg, Onno, Snippert, Hugo J G
Published in Cancer research (Chicago, Ill.) (16.05.2022)
Published in Cancer research (Chicago, Ill.) (16.05.2022)
Get full text
Journal Article
Retrograde movements determine effective stem cell numbers in the intestine
Azkanaz, Maria, Corominas-Murtra, Bernat, Ellenbroek, Saskia I. J., Bruens, Lotte, Webb, Anna T., Laskaris, Dimitrios, Oost, Koen C., Lafirenze, Simona J. A., Annusver, Karl, Messal, Hendrik A., Iqbal, Sharif, Flanagan, Dustin J., Huels, David J., Rojas-Rodríguez, Felipe, Vizoso, Miguel, Kasper, Maria, Sansom, Owen J., Snippert, Hugo J., Liberali, Prisca, Simons, Benjamin D., Katajisto, Pekka, Hannezo, Edouard, van Rheenen, Jacco
Published in Nature (London) (21.07.2022)
Published in Nature (London) (21.07.2022)
Get full text
Journal Article
Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns
Bollen, Yannik, Stelloo, Ellen, van Leenen, Petra, van den Bos, Myrna, Ponsioen, Bas, Lu, Bingxin, van Roosmalen, Markus J., Bolhaqueiro, Ana C. F., Kimberley, Christopher, Mossner, Maximilian, Cross, William C. H., Besselink, Nicolle J. M., van der Roest, Bastiaan, Boymans, Sander, Oost, Koen C., de Vries, Sippe G., Rehmann, Holger, Cuppen, Edwin, Lens, Susanne M. A., Kops, Geert J. P. L., Kloosterman, Wigard P., Terstappen, Leon W. M. M., Barnes, Chris P., Sottoriva, Andrea, Graham, Trevor A., Snippert, Hugo J. G.
Published in Nature genetics (01.08.2021)
Published in Nature genetics (01.08.2021)
Get full text
Journal Article
Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity
Melhem, Hassan, Kaya, Berna, Kaymak, Tanay, Wuggenig, Philipp, Flint, Emilio, Roux, Julien, Oost, Koen C., Cavelti-Weder, Claudia, Balmer, Maria L., Walser, Jean-Claude, Morales, Rodrigo A., Riedel, Christian U., Liberali, Prisca, Villablanca, Eduardo J., Niess, Jan Hendrik
Published in Mucosal immunology (01.03.2022)
Published in Mucosal immunology (01.03.2022)
Get full text
Journal Article