A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
Hampe, Jochen, Schreiber, Stefan, Franke, Andre, Rosenstiel, Philip, Till, Andreas, Teuber, Markus, Huse, Klaus, Albrecht, Mario, Mayr, Gabriele, De La Vega, Francisco M, Briggs, Jason, Günther, Simone, Prescott, Natalie J, Onnie, Clive M, Häsler, Robert, Sipos, Bence, Fölsch, Ulrich R, Lengauer, Thomas, Platzer, Matthias, Mathew, Christopher G, Krawczak, Michael
Published in Nature genetics (01.02.2007)
Published in Nature genetics (01.02.2007)
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Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
Domingues, Francisco S, Vermeire, Séverine, Rutgeerts, Paul, Franke, Andre, Sina, Christian, Rosenstiel, Philip, Wijmenga, Cisca, Sventoraityte, Jurgita, Mayr, Gabriele, Karlsen, Tom H, Nikolaus, Susanna, Balschun, Tobias, Mathew, Christopher G, Stokkers, Pieter C F, Schreiber, Stefan, Albrecht, Mario, Vatn, Morten H, Onnie, Clive M, Ellinghaus, David, Gazouli, Maria, Strachan, David, Nothnagel, Michael, McArdle, Wendy L, Weersma, Rinse K, Krawczak, Michael
Published in Nature genetics (01.11.2008)
Published in Nature genetics (01.11.2008)
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Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
Parkes, Miles, Barrett, Jeffrey C, Prescott, Natalie J, Tremelling, Mark, Anderson, Carl A, Fisher, Sheila A, Roberts, Roland G, Nimmo, Elaine R, Cummings, Fraser R, Soars, Dianne, Drummond, Hazel, Lees, Charlie W, Khawaja, Saud A, Bagnall, Richard, Burke, Denis A, Todhunter, Catherine E, Ahmad, Tariq, Onnie, Clive M, McArdle, Wendy, Strachan, David, Bethel, Graeme, Bryan, Claire, Lewis, Cathryn M, Deloukas, Panos, Forbes, Alastair, Sanderson, Jeremy, Jewell, Derek P, Satsangi, Jack, Mansfield, John C, Cardon, Lon, Mathew, Christopher G
Published in Nature genetics (01.07.2007)
Published in Nature genetics (01.07.2007)
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Journal Article
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
Ouwehand, Willem, Keniry, Andrew, Fisher, Sheila A, Jewell, Derek P, Anderson, Carl A, Prescott, Natalie J, Deloukas, Panos, Blaszczyk, Katarzyna, Mansfield, John C, Mathew, Christopher G, Watkins, Nick, Drummond, Hazel, Cummings, Fraser R, Forbes, Alastair, Barrett, Jeffrey C, Ravindrarajah, Radhi, Sanderson, Jeremy, Inouye, Mike, Hunt, Sarah, Nimmo, Elaine R, Johnson, Christopher, Bumpstead, Suzannah, Hanson, Catherine E, Lobo, Alan, Massey, Dunecan, Cardon, Lon, Ewels, Philip, Satsangi, Jack, Tremelling, Mark, Gwilliam, Rhian, Carter, Martyn, Berzuini, Carlo, Lees, Charlie W, Onnie, Clive M, Parkes, Miles, Lewis, Cathryn M
Published in Nature genetics (01.06.2008)
Published in Nature genetics (01.06.2008)
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Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 ( IL17REL )
Franke, Andre, Balschun, Tobias, Sina, Christian, Ellinghaus, David, Häsler, Robert, Mayr, Gabriele, Albrecht, Mario, Wittig, Michael, Buchert, Eva, Nikolaus, Susanna, Gieger, Christian, Wichmann, H Erich, Sventoraityte, Jurgita, Kupcinskas, Limas, Onnie, Clive M, Gazouli, Maria, Anagnou, Nicholas P, Strachan, David, McArdle, Wendy L, Mathew, Christopher G, Rutgeerts, Paul, Vermeire, Séverine, Vatn, Morten H, Krawczak, Michael, Rosenstiel, Philip, Karlsen, Tom H, Schreiber, Stefan
Published in Nature genetics (01.04.2010)
Published in Nature genetics (01.04.2010)
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Systematic association mapping identifies NELL1 as a novel IBD disease gene
Franke, Andre, Hampe, Jochen, Rosenstiel, Philip, Becker, Christian, Wagner, Florian, Häsler, Robert, Little, Randall D, Huse, Klaus, Ruether, Andreas, Balschun, Tobias, Wittig, Michael, Elsharawy, Abdou, Mayr, Gabriele, Albrecht, Mario, Prescott, Natalie J, Onnie, Clive M, Fournier, Hélène, Keith, Tim, Radelof, Uwe, Platzer, Matthias, Mathew, Christopher G, Stoll, Monika, Krawczak, Michael, Nürnberg, Peter, Schreiber, Stefan
Published in PloS one (08.08.2007)
Published in PloS one (08.08.2007)
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Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship
Anderson, Carl A, Massey, Dunecan C O, Barrett, Jeffrey C, Prescott, Natalie J, Tremelling, Mark, Fisher, Sheila A, Gwilliam, Rhian, Jacob, Jemima, Nimmo, Elaine R, Drummond, Hazel, Lees, Charlie W, Onnie, Clive M, Hanson, Catherine, Blaszczyk, Katarzyna, Ravindrarajah, Radhi, Hunt, Sarah, Varma, Dhiraj, Hammond, Naomi, Lewis, Gregory, Attlesey, Heather, Watkins, Nick, Ouwehand, Willem, Strachan, David, McArdle, Wendy, Lewis, Cathryn M, Lobo, Alan, Sanderson, Jeremy, Jewell, Derek P, Deloukas, Panos, Mansfield, John C, Mathew, Christopher G, Satsangi, Jack, Parkes, Miles
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2009)
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IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease
Tremelling, Mark, Cummings, Fraser, Fisher, Sheila A, Mansfield, John, Gwilliam, Rhian, Keniry, Andrew, Nimmo, Elaine R, Drummond, Hazel, Onnie, Clive M, Prescott, Natalie J, Sanderson, Jeremy, Bredin, Francesca, Berzuini, Carlo, Forbes, Alastair, Lewis, Cathryn M, Cardon, Lon, Deloukas, Panos, Jewell, Derek, Mathew, Christopher G, Parkes, Miles, Satsangi, Jack
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2007)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2007)
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Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease
Prescott, Natalie J., Dominy, Katherine M., Kubo, Michiaki, Lewis, Cathryn M., Fisher, Sheila A., Redon, Richard, Huang, Ni, Stranger, Barbara E., Blaszczyk, Katarzyna, Hudspith, Barry, Parkes, Gareth, Hosono, Naoya, Yamazaki, Keiko, Onnie, Clive M., Forbes, Alastair, Dermitzakis, Emmanouil T., Nakamura, Yusuke, Mansfield, John C., Sanderson, Jeremy, Hurles, Matthew E., Roberts, Roland G., Mathew, Christopher G.
Published in Human molecular genetics (01.05.2010)
Published in Human molecular genetics (01.05.2010)
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Journal Article
A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5
Prescott, Natalie J, Fisher, Sheila A, Franke, Andre, Hampe, Jochen, Onnie, Clive M, Soars, Dianne, Bagnall, Richard, Mirza, Muddassar M, Sanderson, Jeremy, Forbes, Alastair, Mansfield, John C, Lewis, Cathryn M, Schreiber, Stefan, Mathew, Christopher G
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2007)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2007)
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Genetic variation in myosin IXB is associated with ulcerative colitis
van Bodegraven, Adriaan A, Curley, Christine R, Hunt, Karen A, Monsuur, Alienke J, Linskens, Ronald K, Onnie, Clive M, Crusius, J Bart A, Annese, Vito, Latiano, Anna, Silverberg, Mark S, Bitton, Alain, Fisher, Sheila A, Steinhart, A Hilary, Forbes, Alastair, Sanderson, Jeremy, Prescott, Natalie J, Strachan, David P, Playford, Raymond J, Mathew, Christopher G, Wijmenga, Cisca, Daly, Mark J, Rioux, John D, van Heel, David A
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2006)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2006)
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Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and Inflammatory Bowel Disease and their effects on disease behavior: A case‐control and meta‐analysis study
Onnie, Clive M., Fisher, Sheila A., Pattni, Reenal, Sanderson, Jeremy, Forbes, Alastair, Lewis, Cathryn M., Mathew, Christopher G.
Published in Inflammatory bowel diseases (01.04.2006)
Published in Inflammatory bowel diseases (01.04.2006)
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Direct or indirect association in a complex disease: the role of SLC22A4 and SLC22A5 functional variants in Crohn disease
Fisher, Sheila A., Hampe, Jochen, Onnie, Clive M., Daly, Mark J., Curley, Christine, Purcell, Shaun, Sanderson, Jeremy, Mansfield, John, Annese, Vito, Forbes, Alastair, Lewis, Cathryn M., Schreiber, Stefan, Rioux, John D., Mathew, Christopher G.
Published in Human mutation (01.08.2006)
Published in Human mutation (01.08.2006)
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Combined evidence from three large British Association studies rejects TUCAN/CARD8 as an IBD susceptibility gene
Fisher, Sheila A, Mirza, Muddassar M, Onnie, Clive M, Soars, Dianne, Lewis, Cathryn M, Prescott, Natalie J, Mathew, Christopher G, Sanderson, Jeremy, Forbes, Alastair, Todhunter, Catherine, Donaldson, Peter, Mansfield, John
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2007)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2007)
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Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease
Onnie, Clive M, Fisher, Sheila A, Prescott, Natalie J, Mirza, Muddassar M, Green, Peter, Sanderson, Jeremy, Forbes, Alastair, Lewis, Cathryn M, Mathew, Christopher G
Published in European journal of gastroenterology & hepatology (01.01.2008)
Published in European journal of gastroenterology & hepatology (01.01.2008)
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Searching for Genotype-Phenotype Structure: Using Hierarchical Log-Linear Models in Crohn Disease
Chapman, Juliet M., Onnie, Clive M., Prescott, Natalie J., Fisher, Sheila A., Mansfield, John C., Mathew, Christopher G., Lewis, Cathryn M., Verzilli, Claudio J., Whittaker, John C.
Published in American journal of human genetics (13.02.2009)
Published in American journal of human genetics (13.02.2009)
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Journal Article
Mutation, selection, and evolution of the Crohn disease susceptibility gene CARD15
King, Kathy, Sheikh, Mohammed F., Cuthbert, Andrew P., Fisher, Sheila A., Onnie, Clive M., Mirza, Muddassar M., Pattni, Reenal C., Sanderson, Jeremy, Forbes, Alastair, Mansfield, John, Lewis, Cathryn M., Roberts, Roland G., Mathew, Christopher G.
Published in Human mutation (01.01.2006)
Published in Human mutation (01.01.2006)
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Journal Article
Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population
PEARCE, Alexandra V, FISHER, Sheila A, LEWIS, Cathryn M, MATHEW, Christopher G, PRESCOTT, Natalie J, ONNIE, Clive M, PATTNI, Reenal, GREEN, Peter, FORBES, Alastair, MANSFIELD, John, SANDERSON, Jeremy, SCHREIBER, Stefan
Published in International journal of colorectal disease (01.04.2007)
Published in International journal of colorectal disease (01.04.2007)
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Journal Article
Direct or indirect association in a complex disease: the role ofSLC22A4 andSLC22A5 functional variants in Crohn disease
Fisher, Sheila A., Hampe, Jochen, Onnie, Clive M., Daly, Mark J., Curley, Christine, Purcell, Shaun, Sanderson, Jeremy, Mansfield, John, Annese, Vito, Forbes, Alastair, Lewis, Cathryn M., Schreiber, Stefan, Rioux, John D., Mathew, Christopher G.
Published in Human mutation (01.08.2006)
Published in Human mutation (01.08.2006)
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Journal Article
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Burton, Paul R, Clayton, David G, Cardon, Lon R, Craddock, Nick, Deloukas, Panos, Duncanson, Audrey, Kwiatkowski, Dominic P, McCarthy, Mark I, Ouwehand, Willem H, Samani, Nilesh J, Todd, John A, Donnelly, Peter, Barrett, Jeffrey C
Published in Nature (07.06.2007)
Published in Nature (07.06.2007)
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