Ursolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathways
Shanmugam, Muthu K, Ong, Tina H, Kumar, Alan Prem, Lun, Chang K, Ho, Paul C, Wong, Peter T H, Hui, Kam M, Sethi, Gautam
Published in PloS one (12.03.2012)
Published in PloS one (12.03.2012)
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Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3
Dai, Xiaoyun, Ahn, Kwang Seok, Kim, Chulwon, Siveen, Kodappully Sivaraman, Ong, Tina H., Shanmugam, Muthu K., Li, Feng, Shi, Jizhong, Kumar, Alan Prem, Wang, Ling Zhi, Goh, Boon Cher, Magae, Junji, Hui, Kam M., Sethi, Gautam
Published in Molecular oncology (01.04.2015)
Published in Molecular oncology (01.04.2015)
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Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model
Shanmugam, Muthu K., Manu, Kanjoormana A., Ong, Tina H., Ramachandran, Lalitha, Surana, Rohit, Bist, Pradeep, Lim, Lina H.K, Prem Kumar, Alan, Hui, Kam M., Sethi, Gautam
Published in International journal of cancer (01.10.2011)
Published in International journal of cancer (01.10.2011)
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Journal Article
Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo
RAJENDRAN, Peramaiyan, ONG, Tina H, HUI, Kam M, SETHI, Gautam, LUXI CHEN, FENG LI, SHANMUGAM, Muthu K, VALI, Shireen, ABBASI, Taher, KAPOOR, Shweta, SHARMA, Ashish, PREM KUMAR, Alan
Published in Clinical cancer research (15.03.2011)
Published in Clinical cancer research (15.03.2011)
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Journal Article
Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma
Manu, Kanjoormana Aryan, Shanmugam, Muthu K, Ong, Tina H, Subramaniam, Aruljothi, Siveen, Kodappully Sivaraman, Perumal, Ekambaram, Samy, Ramar Perumal, Bist, Pradeep, Lim, Lina H K, Kumar, Alan Prem, Hui, Kam M, Sethi, Gautam
Published in PloS one (05.03.2013)
Published in PloS one (05.03.2013)
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Journal Article
Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3
Subramaniam, Aruljothi, Shanmugam, Muthu K, Ong, Tina H, Li, Feng, Perumal, Ekambaram, Chen, Luxi, Vali, Shireen, Abbasi, Taher, Kapoor, Shweta, Ahn, Kwang Seok, Kumar, Alan Prem, Hui, Kam M, Sethi, Gautam
Published in British journal of pharmacology (01.10.2013)
Published in British journal of pharmacology (01.10.2013)
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Journal Article
Diosgenin attenuates tumor growth and metastasis in transgenic prostate cancer mouse model by negatively regulating both NF-κB/STAT3 signaling cascades
Sikka, Sakshi, Shanmugam, Muthu K., Siveen, Kodappully Sivaraman, Ong, Tina H., Yang, Min Hee, Lee, Jong Hyun, Rajendran, Peramaiyan, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Alahmadi, Tahani Awad, Vali, Shireen, Kumar, Alan Prem, Sethi, Gautam, Wang, Lingzhi, Hui, Kam Man, Ahn, Kwang Seok
Published in European journal of pharmacology (05.09.2021)
Published in European journal of pharmacology (05.09.2021)
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Journal Article
Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers
Li, Feng, Shanmugam, Muthu K, Siveen, Kodappully Sivaraman, Wang, Fan, Ong, Tina H, Loo, Ser Yue, Swamy, Mahadeva M M, Mandal, Somnath, Kumar, Alan Prem, Goh, Boon Cher, Kundu, Tapas, Ahn, Kwang Seok, Wang, Ling Zhi, Hui, Kam Man, Sethi, Gautam
Published in Oncotarget (10.03.2015)
Published in Oncotarget (10.03.2015)
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Journal Article
Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers
Li, Feng, Shanmugam, Muthu K., Siveen, Kodappully Sivaraman, Wang, Fan, Ong, Tina H., Loo, Ser Yue, Swamy, Mahadeva M.M., Mandal, Somnath, Kumar, Alan Prem, Goh, Boon Cher, Kundu, Tapas, Ahn, Kwang Seok, Wang, Ling Zhi, Hui, Kam Man, Sethi, Gautam
Published in Oncotarget (10.03.2015)
Published in Oncotarget (10.03.2015)
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Journal Article
γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model
Siveen, Kodappully Sivaraman, Ahn, Kwang Seok, Ong, Tina H., Shanmugam, Muthu K., Li, Feng, Yap, Wei Ney, Kumar, Alan Prem, Fong, Chee Wai, Tergaonkar, Vinay, Hui, Kam M, Sethi, Gautam
Published in Oncotarget (15.04.2014)
Published in Oncotarget (15.04.2014)
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Journal Article
Abstract 2813: Modulation of Signal Transducer and Activator of Transcription 3 by emodin through the induction of a phosphatase leads to the suppression of HCC growth in orthotopic mouse model
Shanmugam, Muthu K., Ong, Tina H., Peramaiyan, Rajendran, Subramaniam, Aruljothi, Hui, Kam M., Sethi, Gautam
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model
Siveen, Kodappully Sivaraman, Ahn, Kwang Seok, Ong, Tina H, Shanmugam, Muthu K, Li, Feng, Yap, Wei Ney, Kumar, Alan Prem, Fong, Chee Wai, Tergaonkar, Vinay, Hui, Kam M, Sethi, Gautam
Published in Oncotarget (15.04.2014)
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Published in Oncotarget (15.04.2014)
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