Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
Tam, Kevin J, Liu, Liangliang, Hsing, Michael, Dalal, Kush, Thaper, Daksh, McConeghy, Brian, Yenki, Parvin, Bhasin, Satyam, Peacock, James W, Wang, Yuzhuo, Cherkasov, Artem, Rennie, Paul S, Gleave, Martin E, Ong, Christopher J
Published in Scientific reports (25.03.2024)
Published in Scientific reports (25.03.2024)
Get full text
Journal Article
Semaphorin 3C as a Therapeutic Target in Prostate and Other Cancers
Hui, Daniel H F, Tam, Kevin J, Jiao, Ivy Z F, Ong, Christopher J
Published in International journal of molecular sciences (12.02.2019)
Published in International journal of molecular sciences (12.02.2019)
Get full text
Journal Article
SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1
Peacock, James W, Takeuchi, Ario, Hayashi, Norihiro, Liu, Liangliang, Tam, Kevin J, Al Nakouzi, Nader, Khazamipour, Nastaran, Tombe, Tabitha, Dejima, Takashi, Lee, Kevin CK, Shiota, Masaki, Thaper, Daksh, Lee, Wilson CW, Hui, Daniel HF, Kuruma, Hidetoshi, Ivanova, Larissa, Yenki, Parvin, Jiao, Ivy ZF, Khosravi, Shahram, Mui, Alice L‐F, Fazli, Ladan, Zoubeidi, Amina, Daugaard, Mads, Gleave, Martin E, Ong, Christopher J
Published in EMBO molecular medicine (01.02.2018)
Published in EMBO molecular medicine (01.02.2018)
Get full text
Journal Article
Dependency of Tamoxifen Sensitive and Resistant ER + Breast Cancer Cells on Semaphorin 3C (SEMA3C) for Growth
Bhasin, Satyam, Dusek, Christopher, Peacock, James W, Cherkasov, Artem, Wang, Yuzhuo, Gleave, Martin, Ong, Christopher J
Published in Cells (Basel, Switzerland) (25.06.2023)
Published in Cells (Basel, Switzerland) (25.06.2023)
Get full text
Journal Article
Suppression of LIM and SH3 Domain Protein 1 (LASP1) Negatively Regulated by Androgen Receptor Delays Castration Resistant Prostate Cancer Progression
Dejima, Takashi, Imada, Kenjiro, Takeuchi, Ario, Shiota, Masaki, Leong, Jeffrey, Tombe, Tabitha, Tam, Kevin, Fazli, Ladan, Naito, Seiji, Gleave, Martin E., Ong, Christopher J.
Published in The Prostate (01.02.2017)
Published in The Prostate (01.02.2017)
Get full text
Journal Article
Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells
Ong, Christopher J., Ming-Lum, Andrew, Nodwell, Matt, Ghanipour, Ali, Yang, Lu, Williams, David E., Kim, Joseph, Demirjian, Loutfig, Qasimi, Pooran, Ruschmann, Jens, Cao, Li-Ping, Ma, Kewei, Chung, Stephen W., Duronio, Vincent, Andersen, Raymond J., Krystal, Gerald, Mui, Alice L.-F.
Published in Blood (15.09.2007)
Published in Blood (15.09.2007)
Get full text
Journal Article
The role of the metastasis suppressor gene KAI1 in melanoma angiogenesis
Tang, Yun, Bhandaru, Madhuri, Cheng, Yabin, Lu, Jing, Li, Gang, Ong, Christopher J.
Published in Pigment cell and melanoma research (01.11.2015)
Published in Pigment cell and melanoma research (01.11.2015)
Get full text
Journal Article
Borrelidin, a small molecule nitrile-containing macrolide inhibitor of threonyl-tRNA synthetase, is a potent inducer of apoptosis in acute lymphoblastic leukemia
Habibi, Darya, Ogloff, Nadya, Jalili, Reza B., Yost, Arla, Weng, Andrew P., Ghahary, Aziz, Ong, Christopher J.
Published in Investigational new drugs (01.08.2012)
Published in Investigational new drugs (01.08.2012)
Get full text
Journal Article
Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-inflammatory Effects through SHIP1/STAT3 Complexes
Chamberlain, Thomas C., Cheung, Sylvia T., Yoon, Jeff S.J., Ming-Lum, Andrew, Gardill, Bernd R., Shakibakho, Soroush, Dzananovic, Edis, Ban, Fuqiang, Samiea, Abrar, Jawanda, Kamaldeep, Priatel, John, Krystal, Gerald, Ong, Christopher J., Cherkasov, Artem, Andersen, Raymond J., McKenna, Sean A., Van Petegem, Filip, Mui, Alice L-F.
Published in iScience (21.08.2020)
Published in iScience (21.08.2020)
Get full text
Journal Article
PTEN Loss Promotes Mitochondrially Dependent Type II Fas-Induced Apoptosis via PEA-15
Peacock, James W., Palmer, Jodie, Fink, Dieter, Ip, Stephen, Pietras, Eric M., Mui, Alice L.-F., Chung, Stephen W., Gleave, Martin E., Cox, Michael E., Parsons, Ramon, Peter, Marcus E., Ong, Christopher J.
Published in Molecular and Cellular Biology (01.03.2009)
Published in Molecular and Cellular Biology (01.03.2009)
Get full text
Journal Article
Differentiation of mouse embryonic stem cells into endoderm without embryoid body formation
Kim, Peter T W, Hoffman, Brad G, Plesner, Annette, Helgason, Cheryl D, Verchere, C Bruce, Chung, Stephen W, Warnock, Garth L, Mui, Alice L F, Ong, Christopher J
Published in PloS one (30.11.2010)
Published in PloS one (30.11.2010)
Get full text
Journal Article
Inhibition of the phosphatidylinositol 3'-kinase pathway promotes autocrine fas-induced death of phosphatase and tensin homologue-deficient prostate cancer cells
BERTRAM, Jerod, PEACOCK, James W, TAN, Clara, MUI, Alice L-F, CHUNG, Stephen W, GLEAVE, Martin E, DEDHAR, Shoukat, COX, Michael E, ONG, Christopher J
Published in Cancer research (Chicago, Ill.) (01.05.2006)
Published in Cancer research (Chicago, Ill.) (01.05.2006)
Get full text
Journal Article
Selectively targeting the dimerization interface of human androgen receptor with small-molecules to treat castration-resistant prostate cancer
Dalal, Kush, Ban, Fuqiang, Li, Huifang, Morin, Hélène, Roshan-Moniri, Mani, Tam, Kevin J., Shepherd, Ashley, Sharma, Aishwariya, Peacock, James, Carlson, Michael L., LeBlanc, Eric, Perez, Carl, Duong, Franck, Ong, Christopher J., Rennie, Paul S., Cherkasov, Artem
Published in Cancer letters (28.11.2018)
Published in Cancer letters (28.11.2018)
Get full text
Journal Article
Heterochromatin Protein 1α Mediates Development and Aggressiveness of Neuroendocrine Prostate Cancer
Ci, Xinpei, Hao, Jun, Dong, Xin, Choi, Stephen Y, Xue, Hui, Wu, Rebecca, Qu, Sifeng, Gout, Peter W, Zhang, Fang, Haegert, Anne M, Fazli, Ladan, Crea, Francesco, Ong, Christopher J, Zoubeidi, Amina, He, Housheng H, Gleave, Martin E, Collins, Colin C, Lin, Dong, Wang, Yuzhuo
Published in Cancer research (Chicago, Ill.) (15.05.2018)
Published in Cancer research (Chicago, Ill.) (15.05.2018)
Get full text
Journal Article
Semaphorin 3C promotes de novo steroidogenesis in prostate cancer cells
Yenki, Parvin, Bhasin, Satyam, Liu, Liang, Nabavi, Noushin, Cheng, Chi Wing, Tam, Kevin J, Peacock, James W, Adomat, Hans H, Tombe, Tabitha, Fazli, Ladan, Ivanova, Larissa, Dusek, Christopher, Khosravi, Shahram, Guns, Emma S Tomlinson, Wang, Yuzhuo, Buttyan, Ralph, Gleave, Martin E, Ong, Christopher J
Published in Endocrine-related cancer (01.12.2023)
Published in Endocrine-related cancer (01.12.2023)
Get full text
Journal Article