Semaphorin 3C as a Therapeutic Target in Prostate and Other Cancers
Hui, Daniel H F, Tam, Kevin J, Jiao, Ivy Z F, Ong, Christopher J
Published in International journal of molecular sciences (12.02.2019)
Published in International journal of molecular sciences (12.02.2019)
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Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
Tam, Kevin J., Liu, Liangliang, Hsing, Michael, Dalal, Kush, Thaper, Daksh, McConeghy, Brian, Yenki, Parvin, Bhasin, Satyam, Peacock, James W., Wang, Yuzhuo, Cherkasov, Artem, Rennie, Paul S., Gleave, Martin E., Ong, Christopher J.
Published in Scientific reports (25.03.2024)
Published in Scientific reports (25.03.2024)
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Selectively targeting the dimerization interface of human androgen receptor with small-molecules to treat castration-resistant prostate cancer
Dalal, Kush, Ban, Fuqiang, Li, Huifang, Morin, Hélène, Roshan-Moniri, Mani, Tam, Kevin J., Shepherd, Ashley, Sharma, Aishwariya, Peacock, James, Carlson, Michael L., LeBlanc, Eric, Perez, Carl, Duong, Franck, Ong, Christopher J., Rennie, Paul S., Cherkasov, Artem
Published in Cancer letters (28.11.2018)
Published in Cancer letters (28.11.2018)
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Heterochromatin Protein 1α Mediates Development and Aggressiveness of Neuroendocrine Prostate Cancer
Ci, Xinpei, Hao, Jun, Dong, Xin, Choi, Stephen Y, Xue, Hui, Wu, Rebecca, Qu, Sifeng, Gout, Peter W, Zhang, Fang, Haegert, Anne M, Fazli, Ladan, Crea, Francesco, Ong, Christopher J, Zoubeidi, Amina, He, Housheng H, Gleave, Martin E, Collins, Colin C, Lin, Dong, Wang, Yuzhuo
Published in Cancer research (Chicago, Ill.) (15.05.2018)
Published in Cancer research (Chicago, Ill.) (15.05.2018)
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Semaphorin 3C promotes de novo steroidogenesis in prostate cancer cells
Yenki, Parvin, Bhasin, Satyam, Liu, Liang, Nabavi, Noushin, Cheng, Chi Wing, Tam, Kevin J, Peacock, James W, Adomat, Hans H, Tombe, Tabitha, Fazli, Ladan, Ivanova, Larissa, Dusek, Christopher, Khosravi, Shahram, Guns, Emma S Tomlinson, Wang, Yuzhuo, Buttyan, Ralph, Gleave, Martin E, Ong, Christopher J
Published in Endocrine-related cancer (01.12.2023)
Published in Endocrine-related cancer (01.12.2023)
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SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1
Peacock, James W, Takeuchi, Ario, Hayashi, Norihiro, Liu, Liangliang, Tam, Kevin J, Al Nakouzi, Nader, Khazamipour, Nastaran, Tombe, Tabitha, Dejima, Takashi, Lee, Kevin CK, Shiota, Masaki, Thaper, Daksh, Lee, Wilson CW, Hui, Daniel HF, Kuruma, Hidetoshi, Ivanova, Larissa, Yenki, Parvin, Jiao, Ivy ZF, Khosravi, Shahram, Mui, Alice L‐F, Fazli, Ladan, Zoubeidi, Amina, Daugaard, Mads, Gleave, Martin E, Ong, Christopher J
Published in EMBO molecular medicine (01.02.2018)
Published in EMBO molecular medicine (01.02.2018)
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Dependency of Tamoxifen Sensitive and Resistant ER + Breast Cancer Cells on Semaphorin 3C (SEMA3C) for Growth
Bhasin, Satyam, Dusek, Christopher, Peacock, James W, Cherkasov, Artem, Wang, Yuzhuo, Gleave, Martin, Ong, Christopher J
Published in Cells (Basel, Switzerland) (25.06.2023)
Published in Cells (Basel, Switzerland) (25.06.2023)
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eIF4E Is an Adverse Prognostic Marker of Melanoma Patient Survival by Increasing Melanoma Cell Invasion
Khosravi, Shahram, Tam, Kevin J., Ardekani, Gholamreza S., Martinka, Magdalena, McElwee, Kevin J., Ong, Christopher J.
Published in Journal of investigative dermatology (01.05.2015)
Published in Journal of investigative dermatology (01.05.2015)
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Semaphorin 3 C drives epithelial-to-mesenchymal transition, invasiveness, and stem-like characteristics in prostate cells
Tam, Kevin J., Hui, Daniel H. F., Lee, Wilson W., Dong, Mingshu, Tombe, Tabitha, Jiao, Ivy Z. F., Khosravi, Shahram, Takeuchi, Ario, Peacock, James W., Ivanova, Larissa, Moskalev, Igor, Gleave, Martin E., Buttyan, Ralph, Cox, Michael E., Ong, Christopher J.
Published in Scientific reports (13.09.2017)
Published in Scientific reports (13.09.2017)
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Suppression of LIM and SH3 Domain Protein 1 (LASP1) Negatively Regulated by Androgen Receptor Delays Castration Resistant Prostate Cancer Progression
Dejima, Takashi, Imada, Kenjiro, Takeuchi, Ario, Shiota, Masaki, Leong, Jeffrey, Tombe, Tabitha, Tam, Kevin, Fazli, Ladan, Naito, Seiji, Gleave, Martin E., Ong, Christopher J.
Published in The Prostate (01.02.2017)
Published in The Prostate (01.02.2017)
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The third symposium on treatment-induced neuroendocrine prostate cancer: insights and future directions
Wang, Yuzhuo, Scurll, Joshua, Rascón, Itzel Astiazarán, Cui, Cassandra, Ni, Yuchao, Shi, Ace Mingchen, Gangadharannambiar, Priyadarsini, Wang, Yu, Akamatsu, Shusuke, Beltran, Himisha, Cox, Michael, Crea, Francesco, Daugaard, Mads, Dong, Xuesen, Haffner, Michael, He, Hansen, Jachetti, Elena, Kyprianou, Natasha, Li, Benyi, Ong, Christopher E, Rickman, David S, Sen, Triparna, Zhu, Helen He, Zoubeidi, Amina, Gleave, Martin E
Published in Epigenomics (01.09.2024)
Published in Epigenomics (01.09.2024)
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Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells
Ong, Christopher J., Ming-Lum, Andrew, Nodwell, Matt, Ghanipour, Ali, Yang, Lu, Williams, David E., Kim, Joseph, Demirjian, Loutfig, Qasimi, Pooran, Ruschmann, Jens, Cao, Li-Ping, Ma, Kewei, Chung, Stephen W., Duronio, Vincent, Andersen, Raymond J., Krystal, Gerald, Mui, Alice L.-F.
Published in Blood (15.09.2007)
Published in Blood (15.09.2007)
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The role of the metastasis suppressor gene KAI1 in melanoma angiogenesis
Tang, Yun, Bhandaru, Madhuri, Cheng, Yabin, Lu, Jing, Li, Gang, Ong, Christopher J.
Published in Pigment cell and melanoma research (01.11.2015)
Published in Pigment cell and melanoma research (01.11.2015)
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Borrelidin, a small molecule nitrile-containing macrolide inhibitor of threonyl-tRNA synthetase, is a potent inducer of apoptosis in acute lymphoblastic leukemia
Habibi, Darya, Ogloff, Nadya, Jalili, Reza B., Yost, Arla, Weng, Andrew P., Ghahary, Aziz, Ong, Christopher J.
Published in Investigational new drugs (01.08.2012)
Published in Investigational new drugs (01.08.2012)
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Transcriptome-Based Analysis of Molecular Pathways for Clusterin Functions in Kidney Cells
Dairi, Ghida, Guan, Qiunong, Roshan-Moniri, Mani, Collins, Colin C., Ong, Christopher J., Gleave, Martin E., Nguan, Christopher Y.C., Du, Caigan
Published in Journal of cellular physiology (01.12.2016)
Published in Journal of cellular physiology (01.12.2016)
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Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-inflammatory Effects through SHIP1/STAT3 Complexes
Chamberlain, Thomas C., Cheung, Sylvia T., Yoon, Jeff S.J., Ming-Lum, Andrew, Gardill, Bernd R., Shakibakho, Soroush, Dzananovic, Edis, Ban, Fuqiang, Samiea, Abrar, Jawanda, Kamaldeep, Priatel, John, Krystal, Gerald, Ong, Christopher J., Cherkasov, Artem, Andersen, Raymond J., McKenna, Sean A., Van Petegem, Filip, Mui, Alice L-F.
Published in iScience (21.08.2020)
Published in iScience (21.08.2020)
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