Hypouricemic agents reduce indoxyl sulfate excretion by inhibiting the renal transporters OAT1/3 and ABCG2
Taniguchi, Tetsuya, Omura, Koichi, Motoki, Keisuke, Sakai, Miku, Chikamatsu, Noriko, Ashizawa, Naoki, Takada, Tappei, Iwanaga, Takashi
Published in Scientific reports (31.03.2021)
Published in Scientific reports (31.03.2021)
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Journal Article
Ideal pharmacokinetic profile of dotinurad as a selective urate reabsorption inhibitor
Omura, Koichi, Miyata, Kengo, Kobashi, Seiichi, Ito, Azusa, Fushimi, Masahiko, Uda, Junichiro, Sasaki, Tomomitsu, Iwanaga, Takashi, Ohashi, Tetsuo
Published in Drug metabolism and pharmacokinetics (01.06.2020)
Published in Drug metabolism and pharmacokinetics (01.06.2020)
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Journal Article
Pharmacokinetic/pharmacodynamic modeling and simulation of dotinurad, a novel uricosuric agent, in healthy volunteers
Motoki, Keisuke, Igarashi, Takako, Omura, Koichi, Nakatani, Hiroshi, Iwanaga, Takashi, Tamai, Ikumi, Ohashi, Tetsuo
Published in Pharmacology research & perspectives (01.12.2019)
Published in Pharmacology research & perspectives (01.12.2019)
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Journal Article
Metabolic Profile of FYX-051 (4-(5-Pyridin-4-yl-1H-[1,2,4]triazol-3-yl)pyridine-2-carbonitrile) in the Rat, Dog, Monkey, and Human: Identification of N-Glucuronides and N-Glucosides
Nakazawa, Takashi, Miyata, Kengo, Omura, Koichi, Iwanaga, Takashi, Nagata, Osamu
Published in Drug metabolism and disposition (01.11.2006)
Published in Drug metabolism and disposition (01.11.2006)
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Journal Article
Characterization of N-Glucuronidation of 4-(5-Pyridin-4-yl-1H-[1,2,4]triazol-3-yl) pyridine-2-carbonitrile (FYX-051): A New Xanthine Oxidoreductase Inhibitor
OMURA, Koichi, NAKAZAWA, Takashi, SATO, Takahiro, IWANAGA, Takashi, NAGATA, Osamu
Published in Drug metabolism and disposition (01.12.2007)
Published in Drug metabolism and disposition (01.12.2007)
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Journal Article
Identification of Human UDP-Glucuronosyltransferase and Sulfotransferase as Responsible for the Metabolism of Dotinurad, a Novel Selective Urate Reabsorption Inhibitor
Omura, Koichi, Motoki, Keisuke, Kobashi, Seiichi, Miyata, Kengo, Yamano, Katsuhiro, Iwanaga, Takashi
Published in Drug metabolism and disposition (01.11.2021)
Published in Drug metabolism and disposition (01.11.2021)
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Journal Article
Design of Organic-inorganic Hybrid Waveguide
Segawa, Hiroyo, Omura, Koichi, Arai, Yasuhiko, Yoshida, Kazuaki
Published in Journal of Photopolymer Science and Technology (2002)
Published in Journal of Photopolymer Science and Technology (2002)
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Journal Article
LIQUID CRYSTAL DISPLAY DEVICE AND PROJECTION TYPE DISPLAY DEVICE
MIZUGUCHI YOSHIHIRO, TAKAGI HIROSHI, KOBAYASHI HIROSHI, OMURA KOICHI, HIRAKAWA YOSHIHIRO
Year of Publication 08.09.2016
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Year of Publication 08.09.2016
Patent
EFFERVESCENT FOOD PRODUCT
SUZUKI AKIHIRO, OCHI TAIRIN, NEGISHI JUNICHI, OMURA KOICHI, KUWABARA ETSUKO, NAKAGAWA HARUNA, YAMADA MARIKO
Year of Publication 27.10.2014
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Year of Publication 27.10.2014
Patent
Metabolic profile of FYX-051 (4-(5-pyridin-4-yl-1h-[1,2,4]triazol-3-yl)pyridine-2-carbonitrile) Hn the rat, dog, monkey, and human : Identification of N-glucuronides and N-glucosides
NAKAZAWA, Takashi, MIYATA, Kengo, OMURA, Koichi, IWANAGA, Takashi, NAGATA, Osamu
Published in Drug metabolism and disposition (2006)
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Published in Drug metabolism and disposition (2006)
Journal Article