Design of Group IIA Secreted/Synovial Phospholipase A2 Inhibitors: An Oxadiazolone Derivative Suppresses Chondrocyte Prostaglandin E2 Secretion
Ombetta, Jean-Edouard, Thelier, Natacha, Dong, Chang Zhi, Plocki, Stéphanie, Tsagris, Lydia, Rannou, François, Massicot, France, Djimdé, Atimé, El-Hayek, Elissar, Shi, Yiming, Heymans, Françoise, Gresh, Nohad, Chauvet, Caroline
Published in PloS one (01.06.2010)
Published in PloS one (01.06.2010)
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Journal Article
Antioxidative properties of galantamine on neuronal damage induced by hydrogen peroxide in SK–N–SH cells
Ezoulin, Miezan J.M., Ombetta, Jean-Edouard, Dutertre-Catella, Hélène, Warnet, Jean-Michel, Massicot, France
Published in Neurotoxicology (Park Forest South) (01.03.2008)
Published in Neurotoxicology (Park Forest South) (01.03.2008)
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Inhibition of secretory phospholipase A2. 2-Synthesis and structure-activity relationship studies of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one (PMS1062) derivatives specific for group II enzyme
DONG, Chang-Zhi, AHAMADA-HIMIDI, Azali, MASSICOT, France, HEYMANS, Francoise, PLOCKI, Stephanie, AOUN, Darina, TOUAIBIA, Mohamed, MEDDAD-BEL HABICH, Nadia, HUET, Jack, REDEUILH, Catherine, OMBETTA, Jean-Edouard, GODFROID, Jean-Jacques
Published in Bioorganic & medicinal chemistry (15.03.2005)
Published in Bioorganic & medicinal chemistry (15.03.2005)
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Journal Article
Differential effect of PMS777, a new type of acetylcholinesterase inhibitor, and galanthamine on oxidative injury induced in human neuroblastoma SK-N-SH cells
Ezoulin, Miezan J.-M., Li, Juan, Wu, Guirong, Dong, Chang-Zhi, Ombetta, Jean-Edouard, Chen, Hong-Zhuan, Massicot, France, Heymans, Françoise
Published in Neuroscience letters (02.12.2005)
Published in Neuroscience letters (02.12.2005)
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Journal Article
Structure-activity relationships in platelet-activating factor (PAF). 11-From PAF-antagonism to phospholipase A2 inhibition: syntheses and structure-activity relationships in 1-arylsulfamido-2-alkylpiperazines
BINISTI, Carine, ASSOGBA, Léon, TOUBOUL, Estéra, MOUNIER, Carine, HUET, Jack, OMBETTA, Jean-Edouard, CHANG ZHI DONG, REDEUILH, Catherine, HEYMANS, Francoise, GODFROID, Jean-Jacques
Published in European journal of medicinal chemistry (01.10.2001)
Published in European journal of medicinal chemistry (01.10.2001)
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Journal Article
Design of group IIA secreted/synovial phospholipase A(2) inhibitors: an oxadiazolone derivative suppresses chondrocyte prostaglandin E(2) secretion
Ombetta, Jean-Edouard, Thelier, Natacha, Dong, Chang Zhi, Plocki, Stéphanie, Tsagris, Lydia, Rannou, François, Massicot, France, Djimdé, Atimé, El-Hayek, Elissar, Shi, Yiming, Heymans, Françoise, Gresh, Nohad, Chauvet, Caroline
Published in PloS one (01.06.2010)
Published in PloS one (01.06.2010)
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Journal Article
Iododerivative of pargyline: A potential tracer for the exploration of monoamine oxidase sites by SPECT
Lena, Isabelle, Ombetta, Jean-Edouard, Chalon, Sylvie, Dognon, Anne-Marie, Baulieu, Jean-Louis, Frangin, Yves, Garreau, Lucette, Besnard, Jean-Claude, Guilloteau, Denis
Published in Nuclear medicine and biology (01.08.1995)
Published in Nuclear medicine and biology (01.08.1995)
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Synthesis and characterization of [ 125I] N-(2-aminoethyl)-4-iodobenzamide as a selective monoamine oxidase B inhibitor
Rafii, Hamid, Chalon, Sylvie, Ombetta, Jean-Edouard, Frangin, Yves, Garreau, Lucette, Dognon, Anne-Marie, Lena, Isabelle, Bodard, Sylvie, Vilar, Marie-Paule, Besnard, Jean-Claude, Guilloteau, Denis
Published in Nuclear medicine and biology (01.07.1995)
Published in Nuclear medicine and biology (01.07.1995)
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Journal Article
Design of Group IIA Secreted/Synovial Phospholipase A.sub.2 Inhibitors: An Oxadiazolone Derivative Suppresses Chondrocyte Prostaglandin E.sub.2 Secretion
Ombetta, Jean-Edouard, Thelier, Natacha, Dong, Chang Zhi, Plocki, Stéphanie, Tsagris, Lydia, Rannou, François, Massicot, France, Djimdé, Atimé, El-Hayek, Elissar, Shi, Yiming, Heymans, Françoise, Gresh, Nohad, Chauvet, Caroline
Published in PloS one (01.06.2010)
Published in PloS one (01.06.2010)
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Journal Article
Inhibition of secretory phospholipase A2. 1-Design, synthesis and structure-activity relationship studies starting from 4-tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLA2s
ASSOGBA, Léon, AHAMADA-HIMIDI, Azali, GODFROID, Jean-Jacques, DONG, Chang-Zhi, HEYMANS, Francoise, HABICH, Nadia Meddad-Bel, AOUN, Darina, BOUKLI, Latifa, MASSICOT, France, MOUNIER, Carine M, HUET, Jack, LAMOURI, Aazdine, OMBETTA, Jean-Edouard
Published in European journal of medicinal chemistry (01.09.2005)
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Published in European journal of medicinal chemistry (01.09.2005)
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Synthesis of 4′-Iodo-5-methoxyvalerophenone O-(2-aminoethyl)oxime as an agent for exploration of serotoninergic transporter
Branger, Caroline, Garreau, Lucette, Dognon, Anne-Marie, Frangin, Yves, Caillet, Mireille, Ombetta-Goka, Jean-Edouard, Chalon, Sylvie, Besnard, Jean-Claude, Guilloteau, Denis
Published in Nuclear medicine and biology (1995)
Published in Nuclear medicine and biology (1995)
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Journal Article
Molecular Modeling, Design, and Synthesis of Less Lipophilic Derivatives of 3‐(4‐Tetradecyloxybenzyl)‐4 H‐ 1,2,4‐oxadiazol‐5‐one (PMS1062) Specific for Group II Enzyme
Plocki, Stéphanie, Aoun, Darina, Ahamada‐Himidi, Azali, Tavarès‐Camarinha, Fernanda, Dong, Chang‐Zhi, Massicot, France, Huet, Jack, Adolphe‐Pierre, Sylvie, Chau, François, Godfroid, Jean‐Jacques, Gresh, Nohad, Ombetta, Jean Edouard, Heymans, Françoise
Published in European journal of organic chemistry (01.07.2005)
Published in European journal of organic chemistry (01.07.2005)
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Journal Article
Inhibition of secretory phospholipase A 2. 2-Synthesis and structure–activity relationship studies of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4 H-oxadiazol-5-one ( PMS1062) derivatives specific for group II enzyme
Dong, Chang-Zhi, Ahamada-Himidi, Azali, Plocki, Stéphanie, Aoun, Darina, Touaibia, Mohamed, Meddad-Bel Habich, Nadia, Huet, Jack, Redeuilh, Catherine, Ombetta, Jean-Edouard, Godfroid, Jean-Jacques, Massicot, France, Heymans, Françoise
Published in Bioorganic & medicinal chemistry (2005)
Published in Bioorganic & medicinal chemistry (2005)
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Journal Article
Inhibition of secretory phospholipase A 2. 1-Design, synthesis and structure–activity relationship studies starting from 4-tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLA 2s
Assogba, Léon, Ahamada-Himidi, Azali, Habich, Nadia Meddad-Bel, Aoun, Darina, Boukli, Latifa, Massicot, France, Mounier, Carine M., Huet, Jack, Lamouri, Aazdine, Ombetta, Jean-Edouard, Godfroid, Jean-Jacques, Dong, Chang-Zhi, Heymans, Françoise
Published in European journal of medicinal chemistry (2005)
Published in European journal of medicinal chemistry (2005)
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Journal Article
Structure–activity relationships in platelet-activating factor (PAF). 11-From PAF-antagonism to phospholipase A 2 inhibition: syntheses and structure–activity relationships in 1-arylsulfamido-2-alkylpiperazines
Binisti, Carine, Assogba, Léon, Touboul, Estéra, Mounier, Carine, Huet, Jack, Ombetta, Jean-Edouard, Dong, Chang Zhi, Redeuilh, Catherine, Heymans, Françoise, Godfroid, Jean-Jacques
Published in European journal of medicinal chemistry (2001)
Published in European journal of medicinal chemistry (2001)
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Journal Article
Molecular Modeling, Design, and Synthesis of Less Lipophilic Derivatives of 3-(4-Tetradecyloxybenzyl)-4H-1,2,4-oxadiazol-5-one (PMS1062) Specific for Group II Enzyme
Plocki, Stéphanie, Aoun, Darina, Ahamada-Himidi, Azali, Tavarès-Camarinha, Fernanda, Dong, Chang-Zhi, Massicot, France, Huet, Jack, Adolphe-Pierre, Sylvie, Chau, François, Godfroid, Jean-Jacques, Gresh, Nohad, Ombetta, Jean Edouard, Heymans, Françoise
Published in European Journal of Organic Chemistry (01.07.2005)
Published in European Journal of Organic Chemistry (01.07.2005)
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Book Review
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Synthesis and characterization of a new pyrimidine derivative: 5-[1-phenyl-2-(3-chlorophenyl)ethyl]-2,4,6-trichloropyrimidine
Fellahi, Y, Dubois, P, Agafonov, Moussa, F, OmbettaGoka, JE, Guenzet, J, Frangin, Y
Published in Bulletin de la Société chimique de France (01.01.1996)
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Published in Bulletin de la Société chimique de France (01.01.1996)
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