The BACH1 inhibitor ASP8731 inhibits inflammation and vaso-occlusion and induces fetal hemoglobin in sickle cell disease
Belcher, John D, Nataraja, Selvaraj, Abdulla, Fuad, Zhang, Ping, Chen, Chunsheng, Nguyen, Julia, Ruan, Conglin, Singh, Maneet, Demes, Shilpa, Olson, Lyndsay, Stickens, Domi, Stanwix, Jeff, Clarke, Emer, Huang, Yongzhao, Biddle, Margaret, Vercellotti, Gregory M
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Published in Frontiers in medicine (18.04.2023)
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Orally Bioavailable Enzymatic Inhibitor of CD38, MK-0159, Protects against Ischemia/Reperfusion Injury in the Murine Heart
Lagu, Bharat, Wu, Xinyuan, Kulkarni, Santosh, Paul, Rakesh, Becherer, J. David, Olson, Lyndsay, Ravani, Stella, Chatzianastasiou, Athanasia, Papapetropoulos, Andreas, Andrzejewski, Sylvia
Published in Journal of medicinal chemistry (14.07.2022)
Published in Journal of medicinal chemistry (14.07.2022)
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ML-0207/ASP8731: A Novel BACH1 Inhibitor That Induces Fetal Hemoglobin in Treatment of Sickle Cell Disease
Nataraja, Selva, Singh, Maneet, Demes, Shilpa, Olson, Lyndsay, Stanwix, Jeff, Biddle, Margaret, Clarke, Emer, Huang, Yongzhao, Nguyen, Julia, Chen, Chunsheng, Zhang, Ping, Abdulla, Fuad, Vercellotti, Gregory M., Belcher, John D
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Bach1 Inhibitors Reduce Stasis in Townes Sickle Cell Mouse Model
Belcher, John D, Biddle, Margaret, Stickens, Domi, Olson, Lyndsay, Bell, Eric, Chen, Chunsheng, Abdulla, Fuad, Nguyen, Julia, Kiser, Zachary Monroe, Lloyd, Jacob, Vercellotti, Gregory M
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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PPARδ modulation rescues mitochondrial fatty acid oxidation defects in the mdx model of muscular dystrophy
Bell, Eric L, Shine, Robert W, Dwyer, Peter, Olson, Lyndsay, Truong, Jennifer, Fredenburg, Ross, Goddeeris, Matthew, Stickens, Dominique, Tozzo, Effie
Published in Mitochondrion (01.05.2019)
Published in Mitochondrion (01.05.2019)
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