Dendritic Cells in Lupus Are Not Required for Activation of T and B Cells but Promote Their Expansion, Resulting in Tissue Damage
Teichmann, Lino L., Ols, Michelle L., Kashgarian, Michael, Reizis, Boris, Kaplan, Daniel H., Shlomchik, Mark J.
Published in Immunity (Cambridge, Mass.) (14.12.2010)
Published in Immunity (Cambridge, Mass.) (14.12.2010)
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CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling
Henry, Kate L, Kellner, Debra, Bajrami, Bekim, Anderson, John E, Beyna, Mercedes, Bhisetti, Govinda, Cameron, Tom, Capacci, Andrew G, Bertolotti-Ciarlet, Andrea, Feng, Jun, Gao, Benbo, Hopkins, Brian, Jenkins, Tracy, Li, Kejie, May-Dracka, Tricia, Murugan, Paramasivam, Wei, Ru, Zeng, Weike, Allaire, Norm, Buckler, Alan, Loh, Christine, Juhasz, Peter, Lucas, Brian, Ennis, Katelin A, Vollman, Elisabeth, Cahir-McFarland, Ellen, Hett, Erik C, Ols, Michelle L
Published in Science signaling (31.07.2018)
Published in Science signaling (31.07.2018)
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Journal Article
Facultative role for T cells in extrafollicular Toll-like receptor-dependent autoreactive B-cell responses in vivo
Sweet, Rebecca A, Ols, Michelle L, Cullen, Jaime L, Milam, Ashley Viehmann, Yagita, Hideo, Shlomchik, Mark J
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2011)
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Journal Article
348 TIL engineered with membrane-bound IL15 (cytoTIL15™) are enriched for tumor-associated antigen reactivity and demonstrate pharmacologically tunable expansion and persistence in the presence of TAA
Burga, Rachel A, Ocando, Alonso Villasmil, Aksoy, Arman, Pedro, Kyle, Kulkarni, Gauri, Langley, Meghan, Primack, Benjamin, Ross, Theresa, Young, Violet, Tchaicha, Jeremy, Meulen, Jan ter, Ols, Michelle
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
166 Genetically engineered tumor-infiltrating lymphocytes (cytoTIL15) exhibit IL-2-independent persistence and anti-tumor efficacy against melanoma in vivo
Burga, Rachel, Khattar, Mithun, Lajoie, Scott, Pedro, Kyle, Foley, Colleen, Ocando, Alonso Villasmil, Tremblay, Jack, Primack, Benjamin, Langley, Meghan, Thornton, Dan, Tam, Stanley, Brideau, Emily, Ross, Theresa, Wilmes, Gwen, Saha, Sunandan, Helmlinger, Gabriel, Tchaicha, Jeremy, Sethi, Dhruv, Ols, Michelle, Vanasse, Gary, Subramanian, Shyam, Meulen, Jan ter
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Abstract 3580: Enhancing adoptive cell therapies through exogenous regulation
Richardson, Celeste, Elpek, Kutlu, Ols, Michelle, Kassum, Tariq, Shamah, Steve
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract LB072: Tumor-infiltrating lymphocytes (TIL) engineered with membrane-bound IL15 (cytoTIL15 cells) exhibit pharmacologically regulatable signal transduction in cis and trans
Burga, Rachel, Kulkarni, Gauri, Ao, Zheng, Sethi, Dhruv K., ter Meulen, Jan, Ols, Michelle
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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Journal Article
폴리펩티드 페이로드의 기능/풍부성 및 전달의 조절을 위한 조성물 및 시스템
SUN DEXUE, TER MEULEN JAN, SMITH SEAN, LI DAN JUN, OLS MICHELLE, SETHI DHRUV, SCHEBESTA MICHAEL
Year of Publication 28.06.2024
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Year of Publication 28.06.2024
Patent
Abstract LB-013: CAR-Ts armored with small molecule-regulated IL12 or CD40L cassettes for enhanced activity against solid tumors
Ols, Michelle, Schebesta, Michael, Brideau, Emily, Elpek, Kutlu, Fleury, Michelle, Gori, Jennifer, Heller, Scott, Li, Dan Jun, Primack, Benjamin, Reardon, Christopher, Sethi, Dhruv, Storer, Alex, Sun, Dexue, Tran, Karen, Weisman, Elizabeth, Briskin, Michael, Richardson, Celeste, Suri, Vipin, Shamah, Steven
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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막 결합된 인터류킨 15를 갖는 종양 침윤성 림프구및 이의 용도
PEDRO KYLE, TER MEULEN JAN, STORER JAMES ALEXANDER, SUBRAMANIAN SHYAMSUNDAR, OLS MICHELLE, BURGA RACHEL, TCHAICHA JEREMY HATEM, KHATTAR MITHUN
Year of Publication 22.09.2023
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Year of Publication 22.09.2023
Patent
Abstract LB096: IL15-engineered tumor infiltrating lymphocytes (cytoTIL15TM) exhibit activity against autologous tumor cells from multiple solid tumor indications without IL2
Pedro, Kyle D., Burga, Rachel, Ocando, Alonso Villasmil, Langley, Meghan, Kulkarni, Gauri, Ao, Zheng, Primack, Benjamin, Ross, Theresa, Young, Violet, Tchaicha, Jeremy, Ols, Michelle, Meulen, Jan Ter
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Abstract LB065: Tumor-infiltrating lymphocytes (TIL) engineered with regulatable membrane-bound IL15 (mbIL15) and LIGHT (TNFSF14) show enhanced efficacy in fibroblast-containing cold tumors
Koscso, Balazs, Ao, Zheng, Passaro, Carmela, Shah, Nirzari, Ly, Ngoc, Timpug, Patricia, Aksoy, Bulent A., Sun, Dexue, Li, Dan Jun, Sheahan, Kerri-Lynn, Young, Violet, Ross, Theresa, Primack, Benjamin, Langley, Meghan, Tchaicha, Jeremy, Sethi, Dhruv K., ter Meulen, Jan, Ols, Michelle
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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Journal Article
278 Pharmacologically-controlled expression of membrane-bound IL-12 results in T-cell therapy with enhanced potency in preclinical solid tumor models
Smith, Sean, Primack, Benjamin, Ross, Theresa, Timpug, Patricia, Sun, Dexue, Li, Dan Jun, Lajoie, Scott, Young, Violet, Langley, Meghan, Tchaicha, Jeremy, Sethi, Dhruv, Jan ter Meulen, Ols, Michelle
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
Abstract LB101: Novel Drug-responsive domain (DRD)-based regulation technology enables tightly controlled activity of potent membrane-bound IL12 in adoptive cell therapies
Smith, Sean Gregory, Storer, James A., Sun, Dexue, Li, Dan Jun, Primack, Benjamin, Ross, Theresa, LaJoie, Scott, Tchaicha, Jeremy, Sethi, Dhruv, ter Meulen, Jan, Ols, Michelle
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract LB093: Engineering tumor infiltrating lymphocytes from sarcoma and colorectal tumors with membrane bound IL-15 for IL-2 independent expansion and enhanced cytotoxicity against autologous tumor cell lines
Ao, Zheng, Passaro, Carmela, Aksoy, Bulent A., Koscso, Balazs, Burga, Rachel, Pedro, Kyle, Ly, Natasha, Shah, Nirzari, Ocando, Alonso V., Kulkarni, Gauri, Timpug, Trisha, Pollack, Seth M., ter Meulen, Jan, Ols, Michelle L.
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Abstract LB212: Allogeneic, IL-2-independent tumor-infiltrating lymphocytes expressing membrane-bound IL-15 (cytoTIL15࣪) eradicate tumors in a melanoma PDX model through recognition of shared tumor antigens
Tchaicha, Jeremy H., Lajoie, Scott, Burga, Rachel, Ross, Theresa, Primack, Benjamin, Langley, Meghan, Young, Violet, Ocando, Alonso Villasmil, Pedro, Kyle, Tremblay, Jack, Kulkarni, Gauri, Khattar, Mithun, Sethi, Dhruv, Ols, Michelle, Helmlinger, Gabriel, Vanasse, Gary, Subramanian, Shyam, ter Meulen, Jan
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
369 Enhancers of innate and adaptive immunity combine with membrane bound IL15 to increase the efficacy of tumor infiltrating lymphocyte (TIL) therapy for tumors with immunosuppressive microenvironments
Passaro, Carmela, Koscso, Balazs, Smith, Sean, Young, Violet, Ross, Theresa, Primack, Benjamin, Ly, Natasha, Timpug, Patricia, Davoodi, Shabnam, Burga, Rachel, Kulkarni, Gauri, Lajoie, Scott, Langley, Meghan, Shah, Nirzari, Sun, Dexue, Li, Dan Jun, Duan, Raina, Aksoy, Arman, Khattar, Mithun, Tchaicha, Jeremy, Sethi, Dhruv, Jan ter Meulen, Ols, Michelle
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
조율가능한 조절을 위한 인간 탄산 무수화효소 2 조성물 및 방법
SURI VIPIN, RICHARDSON CELESTE, SUN DEXUE, GORI JENNIFER LEAH, SETHI DHRUV KAM, FLEURY MICHELLE LOIS, EZELL TUCKER, OLS MICHELLE LYNN, DOLINSKI BRIAN, HELLER SCOTT FRANCIS, OLINGER GRACE Y, INNISS MARA CHRISTINE, WEISMAN ELIZABETH JANE, ELPEK KUTLU GOKSU, SCHEBESTA MICHAEL, KULKARNI ABHISHEK
Year of Publication 08.12.2021
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Year of Publication 08.12.2021
Patent