Loading…
First-in-human trial of the post-exposure tuberculosis vaccine H56:IC31 in Mycobacterium tuberculosis infected and non-infected healthy adults
Luabeya, Angelique Kany Kany, Kagina, Benjamin M.N., Tameris, Michele D., Geldenhuys, Hennie, Hoff, Soren T., Shi, Zhongkai, Kromann, Ingrid, Hatherill, Mark, Mahomed, Hassan, Hanekom, Willem A., Andersen, Peter, Scriba, Thomas J., Schoeman, Elisma, Krohn, Colleen, Day, Cheryl L., Africa, Hadn, Makhethe, Lebohang, Smit, Erica, Brown, Yolande, Suliman, Sara, Hughes, E. Jane, Bang, Peter, Snowden, Margaret A., McClain, Bruce, Hussey, Gregory D.
Published in Vaccine (07.08.2015)
Published in Vaccine (07.08.2015)
Get full text
Journal Article
Loading…
Loading…
Immunogenicity and safety of an investigational hepatitis B vaccine with a Toll-like receptor 9 agonist adjuvant (HBsAg-1018) compared to a licensed hepatitis B vaccine in healthy adults 40–70 years of age
Heyward, William L., Kyle, Michael, Blumenau, Joseph, Davis, Matthew, Reisinger, Keith, Kabongo, Martin L., Bennett, Sean, Janssen, Robert S., Namini, Hamid, Martin, J. Tyler
Published in Vaccine (04.11.2013)
Published in Vaccine (04.11.2013)
Get full text
Journal Article
Loading…
Safety and immunogenicity of the novel H4:IC31 tuberculosis vaccine candidate in BCG-vaccinated adults: Two phase I dose escalation trials
Norrby, Maria, Vesikari, Timo, Lindqvist, Lars, Maeurer, Markus, Ahmed, Raija, Mahdavifar, Shahnaz, Bennett, Sean, McClain, J. Bruce, Shepherd, Barbara M., Li, Daner, Hokey, David A., Kromann, Ingrid, Hoff, Søren T., Andersen, Peter, de Visser, Adriëtte W., Joosten, Simone A., Ottenhoff, Tom H.M., Andersson, Jan, Brighenti, Susanna
Published in Vaccine (14.03.2017)
Published in Vaccine (14.03.2017)
Get full text
Journal Article
Loading…
Randomized, double-blind, active-controlled study evaluating the safety and immunogenicity of three vaccination schedules and two dose levels of AV7909 vaccine for anthrax post-exposure prophylaxis in healthy adults
Hopkins, Robert J., Kalsi, Gurdyal, Montalvo-Lugo, Victor M., Sharma, Mona, Wu, Yukun, Muse, Derek D., Sheldon, Eric A., Hampel, Frank C., Lemiale, Laurence
Published in Vaccine (19.04.2016)
Published in Vaccine (19.04.2016)
Get full text
Journal Article
Loading…
A phase 1 study of the BCL2-targeted deoxyribonucleic acid inhibitor (DNAi) PNT2258 in patients with advanced solid tumors
Tolcher, Anthony W., Rodrigueza, Wendi V., Rasco, Drew W., Patnaik, Amita, Papadopoulos, Kyriakos P., Amaya, Alex, Moore, Timothy D., Gaylor, Shari K., Bisgaier, Charles L., Sooch, Mina P., Woolliscroft, Michael J., Messmann, Richard A.
Published in Cancer chemotherapy and pharmacology (01.02.2014)
Published in Cancer chemotherapy and pharmacology (01.02.2014)
Get full text
Journal Article
Loading…
Comparison of safety and immunogenicity of two doses of investigational hepatitis B virus surface antigen co-administered with an immunostimulatory phosphorothioate oligodeoxyribonucleotide and three doses of a licensed hepatitis B vaccine in healthy adults 18–55 years of age
Halperin, Scott A., Ward, Brian, Cooper, Curtis, Predy, Gerald, Diaz-Mitoma, Francisco, Dionne, Marc, Embree, Joanne, McGeer, Allison, Zickler, Paul, Moltz, Karl-Heinz, Martz, René, Meyer, Ingo, McNeil, Shelly, Langley, Joanne M., Martins, Eduardo, Heyward, William L., Martin, J. Tyler
Published in Vaccine (28.03.2012)
Published in Vaccine (28.03.2012)
Get full text
Journal Article
Loading…
Clinical Evaluation of Safety and Immunogenicity of PADRE-Cytomegalovirus (CMV) and Tetanus-CMV Fusion Peptide Vaccines With or Without PF03512676 Adjuvant
La Rosa, Corinna, Longmate, Jeff, Lacey, Simon F., Kaltcheva, Teodora, Sharan, Rahul, Marsano, Denise, Kwon, Peter, Drake, Jennifer, Williams, Brenda, Denison, Sharon, Broyer, Suenell, Couture, Larry, Nakamura, Ryotaro, Kelsey, Morris I., Krieg, Arthur M., Diamond, Don J., Zaia, John A.
Published in The Journal of infectious diseases (15.04.2012)
Published in The Journal of infectious diseases (15.04.2012)
Get full text
Journal Article
Loading…
Enhanced early innate and T cell-mediated responses in subjects immunized with Anthrax Vaccine Adsorbed Plus CPG 7909 (AV7909)
Minang, Jacob T., Inglefield, Jon R., Harris, Andrea M., Lathey, Janet L., Alleva, David G., Sweeney, Diane L., Hopkins, Robert J., Lacy, Michael J., Bernton, Edward W.
Published in Vaccine (28.11.2014)
Published in Vaccine (28.11.2014)
Get full text
Journal Article
Loading…
Randomized, double-blind, placebo-controlled, safety and immunogenicity study of 4 formulations of Anthrax Vaccine Adsorbed plus CPG 7909 (AV7909) in healthy adult volunteers
Hopkins, Robert J., Daczkowski, Nancy F., Kaptur, Paulina E., Muse, Derek, Sheldon, Eric, LaForce, Craig, Sari, Suha, Rudge, Thomas L., Bernton, Edward
Published in Vaccine (26.06.2013)
Published in Vaccine (26.06.2013)
Get full text
Journal Article
Loading…
Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid Tumors
Plummer, Ruth, Vidal, Laura, Griffin, Melanie, Lesley, Mark, de Bono, Johann, Coulthard, Sally, Sludden, Julieann, Siu, Lillian L., Chen, Eric X., Oza, Amit M., Reid, Gregory K., McLeod, A. Robert, Besterman, Jeffrey M., Lee, Chooi, Judson, Ian, Calvert, Hilary, Boddy, Alan V.
Published in Clinical cancer research (01.05.2009)
Published in Clinical cancer research (01.05.2009)
Get full text
Journal Article
Loading…
Administration of a Toll-Like Receptor 9 Agonist Decreases the Proviral Reservoir in Virologically Suppressed HIV-Infected Patients
Winckelmann, Anni A., Munk-Petersen, Lærke V., Rasmussen, Thomas A., Melchjorsen, Jesper, Hjelholt, Thomas J., Montefiori, David, Østergaard, Lars, Søgaard, Ole S., Tolstrup, Martin
Published in PloS one (26.04.2013)
Published in PloS one (26.04.2013)
Get full text
Journal Article
Loading…
Marked enhancement of the immune response to BioThrax® (Anthrax Vaccine Adsorbed) by the TLR9 agonist CPG 7909 in healthy volunteers
Rynkiewicz, Dianna, Rathkopf, Melinda, Sim, Iain, Waytes, A. Thomas, Hopkins, Robert J., Giri, Lallan, DeMuria, Deborah, Ransom, Janet, Quinn, James, Nabors, Gary S., Nielsen, Carl J.
Published in Vaccine (26.08.2011)
Published in Vaccine (26.08.2011)
Get full text
Journal Article
Loading…
CPG 7909, an Immunostimulatory TLR9 Agonist Oligodeoxynucleotide, as Adjuvant to Engerix-B HBV Vaccine in Healthy Adults: A Double-Blind Phase I/II Study
COOPER, C.L., DAVIS, H.L., MORRIS, M.L., EFLER, S.M., ADHAMI, M. AL, KRIEG, A.M., CAMERON, D.W., HEATHCOTE, J.
Published in Journal of clinical immunology (01.11.2004)
Published in Journal of clinical immunology (01.11.2004)
Get full text
Journal Article
Loading…
Loading…
Interleukin‐10 derived from macrophages and/or neutrophils regulates the inflammatory response to LPS but not the response to CpG DNA
Siewe, Lisa, Bollati–Fogolin, Mariela, Wickenhauser, Claudia, Krieg, Thomas, Müller, Werner, Roers, Axel
Published in European Journal of Immunology (01.12.2006)
Published in European Journal of Immunology (01.12.2006)
Get full text
Journal Article
Loading…
Phase 1 testing of detoxified LPS/group B meningococcal outer membrane protein vaccine with and without synthetic CPG 7909 adjuvant for the prevention and treatment of sepsis
Cross, Alan S., Greenberg, Nancy, Billington, Melissa, Zhang, Lei, DeFilippi, Christopher, May, Ryan C., Bajwa, Kanwaldeep K.
Published in Vaccine (27.11.2015)
Published in Vaccine (27.11.2015)
Get full text
Journal Article
Loading…
Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma
Link, Brian K, Ballas, Zuhair K, Weisdorf, Daniel, Wooldridge, James E, Bossler, Aaron D, Shannon, Mary, Rasmussen, Wendy L, Krieg, Arthur M, Weiner, George J
Published in Journal of immunotherapy (1997) (01.09.2006)
Published in Journal of immunotherapy (1997) (01.09.2006)
Get more information
Journal Article
Loading…
Immunostimulatory Sequences Regulate Interferon-inducible Genes but not Allergic Airway Responses
Gauvreau, Gail M, Hessel, Edith M, Boulet, Louis-Philippe, Coffman, Robert L, O'Byrne, Paul M
Published in American journal of respiratory and critical care medicine (01.07.2006)
Published in American journal of respiratory and critical care medicine (01.07.2006)
Get full text
Journal Article
Loading…
Immunogenicity and Efficacy of Intramuscular Replication-Defective and Subunit Vaccines against Herpes Simplex Virus Type 2 in the Mouse Genital Model
Delagrave, Simon, Hernandez, Hector, Zhou, Changhong, Hamberger, John F., Mundle, Sophia T., Catalan, John, Baloglu, Simge, Anderson, Stephen F., DiNapoli, Joshua M., Londoño-Hayes, Patricia, Parrington, Mark, Almond, Jeffrey, Kleanthous, Harry
Published in PloS one (11.10.2012)
Published in PloS one (11.10.2012)
Get full text
Journal Article