DSP-6745, a novel 5-hydroxytryptamine modulator with rapid antidepressant, anxiolytic, antipsychotic and procognitive effects
Kitaichi, Maiko, Kato, Taro, Oki, Hitomi, Tatara, Ayaka, Kawada, Takuya, Miyazaki, Kenji, Ishikawa, Chihiro, Kaneda, Katsuyuki, Shimizu, Isao
Published in Psychopharmacology (01.11.2024)
Published in Psychopharmacology (01.11.2024)
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Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity
Ishibashi, Tadashi, Horisawa, Tomoko, Tokuda, Kumiko, Ishiyama, Takeo, Ogasa, Masaaki, Tagashira, Rie, Matsumoto, Kenji, Nishikawa, Hiroyuki, Ueda, Yoko, Toma, Satoko, Oki, Hitomi, Tanno, Norihiko, Saji, Ikutaro, Ito, Akira, Ohno, Yukihiro, Nakamura, Mitsutaka
Published in The Journal of pharmacology and experimental therapeutics (01.07.2010)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2010)
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Discovery of DSP-1053, a novel benzylpiperidine derivative with potent serotonin transporter inhibitory activity and partial 5-HT1A receptor agonistic activity
Yoshinaga, Hidefumi, Nishida, Tomoaki, Sasaki, Izumi, Kato, Taro, Oki, Hitomi, Yabuuchi, Kazuki, Toyoda, Tomohiro
Published in Bioorganic & medicinal chemistry (01.05.2018)
Published in Bioorganic & medicinal chemistry (01.05.2018)
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Application of cytochrome P450 reactivity on the characterization of chemical compounds and its association with repeated-dose toxicity
Watanabe, Michiko, Sasaki, Takamitsu, Takeshita, Jun-ichi, Kushida, Madoka, Shimizu, Yuki, Oki, Hitomi, Kitsunai, Yoko, Nakayama, Haruka, Saruhashi, Hitomi, Ogura, Rui, Shizu, Ryota, Hosaka, Takuomi, Yoshinari, Kouichi
Published in Toxicology and applied pharmacology (01.02.2020)
Published in Toxicology and applied pharmacology (01.02.2020)
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Discovery of SMP-304, a novel benzylpiperidine derivative with serotonin transporter inhibitory activity and 5-HT1A weak partial agonistic activity showing the antidepressant-like effect
Yoshinaga, Hidefumi, Masumoto, Shuji, Koyama, Koji, Kinomura, Naoya, Matsumoto, Yuji, Kato, Taro, Baba, Satoko, Matsumoto, Kenji, Horisawa, Tomoko, Oki, Hitomi, Yabuuchi, Kazuki, Kodo, Toru
Published in Bioorganic & medicinal chemistry (01.01.2017)
Published in Bioorganic & medicinal chemistry (01.01.2017)
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Journal Article
Discovery of DSP-1053, a novel benzylpiperidine derivative with potent serotonin transporter inhibitory activity and partial 5-HT 1A receptor agonistic activity
Yoshinaga, Hidefumi, Nishida, Tomoaki, Sasaki, Izumi, Kato, Taro, Oki, Hitomi, Yabuuchi, Kazuki, Toyoda, Tomohiro
Published in Bioorganic & medicinal chemistry (01.05.2018)
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Published in Bioorganic & medicinal chemistry (01.05.2018)
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Discriminative models using molecular descriptors for predicting increased serum ALT levels in repeated-dose toxicity studies of rats
Takeshita, Jun-ichi, Nakayama, Haruka, Kitsunai, Yoko, Tanabe, Misako, Oki, Hitomi, Sasaki, Takamitsu, Yoshinari, Kouichi
Published in Computational toxicology (01.05.2018)
Published in Computational toxicology (01.05.2018)
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Journal Article
Discovery of SMP-304, a novel benzylpiperidine derivative with serotonin transporter inhibitory activity and 5-HT 1A weak partial agonistic activity showing the antidepressant-like effect
Yoshinaga, Hidefumi, Masumoto, Shuji, Koyama, Koji, Kinomura, Naoya, Matsumoto, Yuji, Kato, Taro, Baba, Satoko, Matsumoto, Kenji, Horisawa, Tomoko, Oki, Hitomi, Yabuuchi, Kazuki, Kodo, Toru
Published in Bioorganic & medicinal chemistry (01.01.2017)
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Published in Bioorganic & medicinal chemistry (01.01.2017)
Journal Article
Pharmacological Profile of Lurasidone, a Novel Antipsychotic Agent with Potent 5-Hydroxytryptamine 7 (5-HT 7 ) and 5-HT 1A Receptor Activity
Ishibashi, Tadashi, Horisawa, Tomoko, Tokuda, Kumiko, Ishiyama, Takeo, Ogasa, Masaaki, Tagashira, Rie, Matsumoto, Kenji, Nishikawa, Hiroyuki, Ueda, Yoko, Toma, Satoko, Oki, Hitomi, Tanno, Norihiko, Saji, Ikutaro, Ito, Akira, Ohno, Yukihiro, Nakamura, Mitsutaka
Published in The Journal of pharmacology and experimental therapeutics (01.07.2010)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2010)
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