Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT
Yamauchi, Tomoaki, Okano, Yumi, Terada, Daishu, Yasukochi, Sai, Tsuruta, Akito, Tsurudome, Yuya, Ushijima, Kentaro, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro
Published in Cancer & metabolism (07.08.2024)
Published in Cancer & metabolism (07.08.2024)
Get full text
Journal Article
Oncogenic accumulation of cysteine promotes cancer cell proliferation by regulating the translation of D-type cyclins
Okano, Yumi, Yamauchi, Tomoaki, Fukuzaki, Runa, Tsuruta, Akito, Yoshida, Yuya, Tsurudome, Yuya, Ushijima, Kentaro, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro
Published in The Journal of biological chemistry (01.11.2024)
Published in The Journal of biological chemistry (01.11.2024)
Get full text
Journal Article
Mechanism and pathological significance of cysteine metabolic reprogramming associated with hepatocarcinogenesis
Tomoaki, Yamauchi, Okano, Yumi, Terada, Daisyu, Tsuruta, Akito, Koyanagi, Satoru, Ohdo, Shigehiro
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2023)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2023)
Get full text
Journal Article