Aberrant protein S -nitrosylation contributes to the pathophysiology of neurodegenerative diseases
Nakamura, Tomohiro, Prikhodko, Olga A, Pirie, Elaine, Nagar, Saumya, Akhtar, Mohd Waseem, Oh, Chang-Ki, McKercher, Scott R, Ambasudhan, Rajesh, Okamoto, Shu-ichi, Lipton, Stuart A
Published in Neurobiology of disease (01.12.2015)
Published in Neurobiology of disease (01.12.2015)
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Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1
Satoh, Takumi, Kosaka, Kunio, Itoh, Ken, Kobayashi, Akira, Yamamoto, Masayuki, Shimojo, Yosuke, Kitajima, Chieko, Cui, Jiankun, Kamins, Joshua, Okamoto, Shu-ichi, Izumi, Masanori, Shirasawa, Takuji, Lipton, Stuart A
Published in Journal of neurochemistry (01.02.2008)
Published in Journal of neurochemistry (01.02.2008)
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Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin
Talantova, Maria, Kaul, Marcus, Yao, Dongdong, Xia, Peng, Ehrnhoefer, Dagmar E, Zaidi, Rameez, Lipton, Stuart A, Graham, Rona K, Tong, Gary, Zhang, Dongxian, Clemente, Arjay, Okamoto, Shu-ichi, Hayden, Michael R, Pouladi, Mahmoud A, Vincent Chen, H-S
Published in Nature medicine (01.12.2009)
Published in Nature medicine (01.12.2009)
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Transnitrosylation of XIAP Regulates Caspase-Dependent Neuronal Cell Death
Nakamura, Tomohiro, Wang, Lei, Wong, Catherine C.L., Scott, Fiona L., Eckelman, Brendan P., Han, Xuemei, Tzitzilonis, Christos, Meng, Fanjun, Gu, Zezong, Holland, Emily A., Clemente, Arjay T., Okamoto, Shu-ichi, Salvesen, Guy S., Riek, Roland, Yates, John R., Lipton, Stuart A.
Published in Molecular cell (30.07.2010)
Published in Molecular cell (30.07.2010)
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Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo
Li, Hao, Radford, Jonathan C, Ragusa, Michael J, Shea, Katherine L, McKercher, Scott R, Zaremba, Jeffrey D, Soussou, Walid, Nie, Zhiguo, Kang, Yeon-Joo, Nakanishi, Nobuki, Okamoto, Shu-ichi, Roberts, Amanda J, Schwarz, John J, Lipton, Stuart A
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2008)
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MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress
Nagar, Saumya, Noveral, Sarah M., Trudler, Dorit, Lopez, Kevin M., McKercher, Scott R., Han, Xuemei, Yates, John R., Piña-Crespo, Juan C., Nakanishi, Nobuki, Satoh, Takumi, Okamoto, Shu-ichi, Lipton, Stuart A.
Published in Proceedings of the National Academy of Sciences - PNAS (16.05.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (16.05.2017)
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NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model
Okamoto, Shu-ichi, Prikhodko, Olga, Pina-Crespo, Juan, Adame, Anthony, McKercher, Scott R., Brill, Laurence M., Nakanishi, Nobuki, Oh, Chang-ki, Nakamura, Tomohiro, Masliah, Eliezer, Lipton, Stuart A.
Published in Neurobiology of disease (01.07.2019)
Published in Neurobiology of disease (01.07.2019)
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S-Nitrosylation-Mediated Redox Transcriptional Switch Modulates Neurogenesis and Neuronal Cell Death
Okamoto, Shu-ichi, Nakamura, Tomohiro, Cieplak, Piotr, Chan, Shing Fai, Kalashnikova, Evgenia, Liao, Lujian, Saleem, Sofiyan, Han, Xuemei, Clemente, Arjay, Nutter, Anthony, Sances, Sam, Brechtel, Christopher, Haus, Daniel, Haun, Florian, Sanz-Blasco, Sara, Huang, Xiayu, Li, Hao, Zaremba, Jeffrey D., Cui, Jiankun, Gu, Zezong, Nikzad, Rana, Harrop, Anne, McKercher, Scott R., Godzik, Adam, Yates, John R., Lipton, Stuart A.
Published in Cell reports (Cambridge) (10.07.2014)
Published in Cell reports (Cambridge) (10.07.2014)
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Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease
Tu, Shichun, Okamoto, Shu-ichi, Lipton, Stuart A, Xu, Huaxi
Published in Molecular neurodegeneration (14.11.2014)
Published in Molecular neurodegeneration (14.11.2014)
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Antiapoptotic Role of the p38 Mitogen-Activated Protein Kinase-Myocyte Enhancer Factor 2 Transcription Factor Pathway during Neuronal Differentiation
Okamoto, Shu-Ichi, Krainc, Dimitri, Sherman, Katerina, Lipton, Stuart A.
Published in Proceedings of the National Academy of Sciences - PNAS (20.06.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (20.06.2000)
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Aberrant Protein S-Nitrosylation in Neurodegenerative Diseases
Nakamura, Tomohiro, Tu, Shichun, Akhtar, Mohd Waseem, Sunico, Carmen R., Okamoto, Shu-ichi, Lipton, Stuart A.
Published in Neuron (Cambridge, Mass.) (22.05.2013)
Published in Neuron (Cambridge, Mass.) (22.05.2013)
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Cell Spreading Controls Endoplasmic and Nuclear Calcium: A Physical Gene Regulation Pathway from the Cell Surface to the Nucleus
Itano, Naoki, Okamoto, Shu-ichi, Zhang, Dongxian, Lipton, Stuart A., Ruoslahti, Erkki
Published in Proceedings of the National Academy of Sciences - PNAS (29.04.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (29.04.2003)
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Transcriptional profiling of MEF2-regulated genes in human neural progenitor cells derived from embryonic stem cells
Chan, Shing Fai, Huang, Xiayu, McKercher, Scott R., Zaidi, Rameez, Okamoto, Shu-ichi, Nakanishi, Nobuki, Lipton, Stuart A.
Published in Genomics data (01.03.2015)
Published in Genomics data (01.03.2015)
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Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription
Ryan, Scott D., Dolatabadi, Nima, Chan, Shing Fai, Zhang, Xiaofei, Akhtar, Mohd Waseem, Parker, James, Soldner, Frank, Sunico, Carmen R., Nagar, Saumya, Talantova, Maria, Lee, Brian, Lopez, Kevin, Nutter, Anthony, Shan, Bing, Molokanova, Elena, Zhang, Yaoyang, Han, Xuemei, Nakamura, Tomohiro, Masliah, Eliezer, Yates, John R., Nakanishi, Nobuki, Andreyev, Aleksander Y., Okamoto, Shu-ichi, Jaenisch, Rudolf, Ambasudhan, Rajesh, Lipton, Stuart A.
Published in Cell (05.12.2013)
Published in Cell (05.12.2013)
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Dominant-Interfering Forms of MEF2 Generated by Caspase Cleavage Contribute to NMDA-Induced Neuronal Apoptosis
Okamoto, Shu-ichi, Li, Zhen, Ju, Chung, Schölzke, Marion N., Mathews, Emily, Cui, Jiankun, Salvesen, Guy S., Bossy-Wetzel, Ella, Lipton, Stuart A.
Published in Proceedings of the National Academy of Sciences - PNAS (19.03.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (19.03.2002)
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Molecular mechanism of interleukin-8 gene expression
Mukaida, Naofumi, Okamoto, Shu‐ichi, Ishikawa, Yuji, Matsushima, Kouji
Published in Journal of leukocyte biology (01.11.1994)
Published in Journal of leukocyte biology (01.11.1994)
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Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency
Nagar, Saumya, Trudler, Dorit, McKercher, Scott R, Piña-Crespo, Juan, Nakanishi, Nobuki, Okamoto, Shu-Ichi, Lipton, Stuart A
Published in Investigative ophthalmology & visual science (01.07.2017)
Published in Investigative ophthalmology & visual science (01.07.2017)
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HIV/gp120 decreases adult neural progenitor cell proliferation via checkpoint kinase-mediated cell-cycle withdrawal and G1 arrest
Okamoto, Shu-ichi, Kang, Yeon-Joo, Brechtel, Christopher W, Siviglia, Elisa, Russo, Rossella, Clemente, Arjay, Harrop, Anne, McKercher, Scott, Kaul, Marcus, Lipton, Stuart A
Published in Cell stem cell (16.08.2007)
Published in Cell stem cell (16.08.2007)
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ATM-dependent phosphorylation of MEF2D promotes neuronal survival after DNA damage
Chan, Shing Fai, Sances, Sam, Brill, Laurence M, Okamoto, Shu-Ichi, Zaidi, Rameez, McKercher, Scott R, Akhtar, Mohd W, Nakanishi, Nobuki, Lipton, Stuart A
Published in The Journal of neuroscience (26.03.2014)
Published in The Journal of neuroscience (26.03.2014)
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