PRC2 Components Maintain DNA Hypermethylation of the Upstream Promoter and Regulate Robo4 Expression in Endothelial Cells
Izawa, Kohei, Shirakura, Keisuke, Kakiuchi, Koji, Funahashi, Nobuaki, Maekawa, Naoki, Hino, Nobumasa, Tanaka, Toru, Doi, Takefumi, Okada, Yoshiaki
Published in Biological & pharmaceutical bulletin (01.04.2020)
Published in Biological & pharmaceutical bulletin (01.04.2020)
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Safety and efficacy of an anti-claudin-5 monoclonal antibody to increase blood–brain barrier permeability for drug delivery to the brain in a non-human primate
Tachibana, Keisuke, Hashimoto, Yosuke, Shirakura, Keisuke, Okada, Yoshiaki, Hirayama, Ryuichi, Iwashita, Yumi, Nishino, Itsuki, Ago, Yukio, Takeda, Hiroyuki, Kuniyasu, Hiroki, Kondoh, Masuo
Published in Journal of controlled release (10.08.2021)
Published in Journal of controlled release (10.08.2021)
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Claudin-5-Binders Enhance Permeation of Solutes across the Blood-Brain Barrier in a Mammalian Model
Hashimoto, Yosuke, Shirakura, Keisuke, Okada, Yoshiaki, Takeda, Hiroyuki, Endo, Kohki, Tamura, Maki, Watari, Akihiro, Sadamura, Yoshifusa, Sawasaki, Tatsuya, Doi, Takefumi, Yagi, Kiyohito, Kondoh, Masuo
Published in The Journal of pharmacology and experimental therapeutics (01.11.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2017)
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Yes‐associated protein activation potentiates glycogen synthase kinase‐3 inhibitor‐induced proliferation of neonatal cardiomyocytes and iPS cell‐derived cardiomyocytes
Kametani, Yusuke, Tanaka, Shota, Wada, Yuriko, Suzuki, Shota, Umeda, Ayaka, Nishinaka, Kosuke, Okada, Yoshiaki, Maeda, Makiko, Miyagawa, Shigeru, Sawa, Yoshiki, Obana, Masanori, Fujio, Yasushi
Published in Journal of cellular physiology (01.05.2022)
Published in Journal of cellular physiology (01.05.2022)
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World Health Organization International Standard to harmonize assays for detection of hepatitis E virus RNA
Baylis, Sally A, Blümel, Johannes, Mizusawa, Saeko, Matsubayashi, Keiji, Sakata, Hidekatsu, Okada, Yoshiaki, Nübling, C Micha, Hanschmann, Kay-Martin O
Published in Emerging infectious diseases (01.05.2013)
Published in Emerging infectious diseases (01.05.2013)
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Engineered membrane protein antigens successfully induce antibodies against extracellular regions of claudin-5
Hashimoto, Yosuke, Zhou, Wei, Hamauchi, Kohtaroh, Shirakura, Keisuke, Doi, Takefumi, Yagi, Kiyohito, Sawasaki, Tatsuya, Okada, Yoshiaki, Kondoh, Masuo, Takeda, Hiroyuki
Published in Scientific reports (30.05.2018)
Published in Scientific reports (30.05.2018)
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The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells
Zhang, Lidan, Noguchi, Yu-taro, Nakayama, Hiroyuki, Kaji, Takayuki, Tsujikawa, Kazutake, Ikemoto-Uezumi, Madoka, Uezumi, Akiyoshi, Okada, Yoshiaki, Doi, Takefumi, Watanabe, Shuichi, Braun, Thomas, Fujio, Yasushi, Fukada, So-ichiro
Published in Cell reports (Cambridge) (19.11.2019)
Published in Cell reports (Cambridge) (19.11.2019)
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Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models
Morita, Maaya, Yoneda, Aki, Tokunoh, Nagisa, Masaki, Tatsumi, Shirakura, Keisuke, Kinoshita, Mayumi, Hashimoto, Rina, Shigesada, Naoya, Takahashi, Junya, Tachibana, Masashi, Tanaka, Shota, Obana, Masanori, Hino, Nobumasa, Ikawa, Masahito, Tsujikawa, Kazutake, Ono, Chikako, Matsuura, Yoshiharu, Kidoya, Hiroyasu, Takakura, Nobuyuki, Kubota, Yoshiaki, Doi, Takefumi, Takayama, Kazuo, Yoshioka, Yasuo, Fujio, Yasushi, Okada, Yoshiaki
Published in Proceedings of the National Academy of Sciences - PNAS (17.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (17.01.2023)
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Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires Hes1 to bind diverse DNA sites
Noguchi, Yu-Taro, Nakamura, Miki, Hino, Nobumasa, Nogami, Jumpei, Tsuji, Sayaka, Sato, Takahiko, Zhang, Lidan, Tsujikawa, Kazutake, Tanaka, Toru, Izawa, Kohei, Okada, Yoshiaki, Doi, Takefumi, Kokubo, Hiroki, Harada, Akihito, Uezumi, Akiyoshi, Gessler, Manfred, Ohkawa, Yasuyuki, Fukada, So-Ichiro
Published in Development (Cambridge) (20.02.2019)
Published in Development (Cambridge) (20.02.2019)
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Arid5a/IL-6/PAI-1 Signaling Is Involved in the Pathogenesis of Lipopolysaccharide-Induced Kidney Injury
Tanaka, Koki, Harada, Hiroki, Kamuro, Hiroyasu, Sakai, Hibiki, Yamamoto, Ayaha, Tomimatsu, Masashi, Ikeda, Akari, Chosokabe, Renya, Tanaka, Shota, Okada, Yoshiaki, Fujio, Yasushi, Obana, Masanori
Published in Biological & pharmaceutical bulletin (01.12.2023)
Published in Biological & pharmaceutical bulletin (01.12.2023)
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The Robo4-TRAF7 complex suppresses endothelial hyperpermeability in inflammation
Shirakura, Keisuke, Ishiba, Ryosuke, Kashio, Taito, Funatsu, Risa, Tanaka, Toru, Fukada, So-Ichiro, Ishimoto, Kenji, Hino, Nobumasa, Kondoh, Masuo, Ago, Yukio, Fujio, Yasushi, Yano, Kiichiro, Doi, Takefumi, Aird, William C, Okada, Yoshiaki
Published in Journal of cell science (02.01.2019)
Published in Journal of cell science (02.01.2019)
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Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling
Tomimatsu, Masashi, Matsumoto, Kotaro, Ashizuka, Moe, Kumagai, Shohei, Tanaka, Shota, Nakae, Takafumi, Yokota, Kosei, Kominami, Shunsuke, Kajiura, Ryota, Okuzaki, Daisuke, Motooka, Daisuke, Shiraishi, Aki, Abe, Takaya, Matsuda, Hideo, Okada, Yoshiaki, Maeda, Makiko, Seno, Shigeto, Obana, Masanori, Fujio, Yasushi
Published in Scientific reports (05.10.2022)
Published in Scientific reports (05.10.2022)
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Endothelial Robo4 regulates IL-6 production by endothelial cells and monocytes via a crosstalk mechanism in inflammation
Shirakura, Keisuke, Ishiba, Ryosuke, Kashio, Taito, Sakai, Miki, Fukushima, Yu, Yamamoto, Nana, Manabe, Shiori, Shigesada, Naoya, Tanaka, Toru, Hino, Nobumasa, Aird, William C., Doi, Takefumi, Okada, Yoshiaki
Published in Biochemical and biophysical research communications (01.01.2018)
Published in Biochemical and biophysical research communications (01.01.2018)
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Ubiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase Activity
Ishimoto, Kenji, Kawamata, Natsuko, Uchihara, Yoshie, Okubo, Moeka, Fujimoto, Reiko, Gotoh, Eiko, Kakinouchi, Keisuke, Mizohata, Eiichi, Hino, Nobumasa, Okada, Yoshiaki, Mochizuki, Yasuhiro, Tanaka, Toshiya, Hamakubo, Takao, Sakai, Juro, Kodama, Tatsuhiko, Inoue, Tsuyoshi, Tachibana, Keisuke, Doi, Takefumi
Published in PloS one (31.10.2016)
Published in PloS one (31.10.2016)
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Highly Regio- and Stereoselective Synthesis of Multialkylated Olefins through Carbozirconation of Alkynylboronates and Sequential Negishi and Suzuki-Miyaura Coupling Reactions
Nishihara, Yasushi, Okada, Yoshiaki, Jiao, Jiao, Suetsugu, Masato, Lan, Ming-Tzu, Kinoshita, Megumi, Iwasaki, Masayuki, Takagi, Kentaro
Published in Angewandte Chemie International Edition (05.09.2011)
Published in Angewandte Chemie International Edition (05.09.2011)
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Runx1 is upregulated by STAT3 and promotes proliferation of neonatal rat cardiomyocytes
Suzuki, Shota, Tanaka, Shota, Kametani, Yusuke, Umeda, Ayaka, Nishinaka, Kosuke, Egawa, Kaho, Okada, Yoshiaki, Obana, Masanori, Fujio, Yasushi
Published in Physiological reports (01.12.2023)
Published in Physiological reports (01.12.2023)
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Journal Article
ETV2-TET1/TET2 Complexes Induce Endothelial Cell-Specific Robo4 Expression via Promoter Demethylation
Tanaka, Toru, Izawa, Kohei, Maniwa, Yusuke, Okamura, Maki, Okada, Atsumasa, Yamaguchi, Tomoko, Shirakura, Keisuke, Maekawa, Naoki, Matsui, Hayato, Ishimoto, Kenji, Hino, Nobumasa, Nakagawa, Osamu, Aird, William C., Mizuguchi, Hiroyuki, Kawabata, Kenji, Doi, Takefumi, Okada, Yoshiaki
Published in Scientific reports (04.04.2018)
Published in Scientific reports (04.04.2018)
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