Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy
Tong, Mingming, Saito, Toshiro, Zhai, Peiyong, Oka, Shin-ichi, Mizushima, Wataru, Nakamura, Michinari, Ikeda, Shohei, Shirakabe, Akihiro, Sadoshima, Junichi
Published in Circulation research (26.04.2019)
Published in Circulation research (26.04.2019)
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Journal Article
Alternative Mitophagy Protects the Heart Against Obesity-Associated Cardiomyopathy
Tong, Mingming, Saito, Toshiro, Zhai, Peiyong, Oka, Shin-ichi, Mizushima, Wataru, Nakamura, Michinari, Ikeda, Shohei, Shirakabe, Akihiro, Sadoshima, Junichi
Published in Circulation research (03.12.2021)
Published in Circulation research (03.12.2021)
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Journal Article
An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia
Saito, Toshiro, Nah, Jihoon, Oka, Shin-Ichi, Mukai, Risa, Monden, Yoshiya, Maejima, Yasuhiro, Ikeda, Yoshiyuki, Sciarretta, Sebastiano, Liu, Tong, Li, Hong, Baljinnyam, Erdene, Fraidenraich, Diego, Fritzky, Luke, Zhai, Peiyong, Ichinose, Shizuko, Isobe, Mitsuaki, Hsu, Chiao-Po, Kundu, Mondira, Sadoshima, Junichi
Published in The Journal of clinical investigation (01.02.2019)
Published in The Journal of clinical investigation (01.02.2019)
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Journal Article
YAP mediates compensatory cardiac hypertrophy through aerobic glycolysis in response to pressure overload
Kashihara, Toshihide, Mukai, Risa, Oka, Shin-Ichi, Zhai, Peiyong, Nakada, Yasuki, Yang, Zhi, Mizushima, Wataru, Nakahara, Tsutomu, Warren, Junco S, Abdellatif, Maha, Sadoshima, Junichi
Published in The Journal of clinical investigation (15.03.2022)
Published in The Journal of clinical investigation (15.03.2022)
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Journal Article
KLF5 Is Induced by FOXO1 and Causes Oxidative Stress and Diabetic Cardiomyopathy
Kyriazis, Ioannis D., Hoffman, Matthew, Gaignebet, Lea, Lucchese, Anna Maria, Markopoulou, Eftychia, Palioura, Dimitra, Wang, Chao, Bannister, Thomas D., Christofidou-Solomidou, Melpo, Oka, Shin-ichi, Sadoshima, Junichi, Koch, Walter J., Goldberg, Ira J., Yang, Vincent W., Bialkowska, Agnieszka B., Kararigas, Georgios, Drosatos, Konstantinos
Published in Circulation research (05.02.2021)
Published in Circulation research (05.02.2021)
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Journal Article
Correlates of neutralizing/SARS-CoV-2-S1-binding antibody response with adverse effects and immune kinetics in BNT162b2-vaccinated individuals
Maeda, Kenji, Amano, Masayuki, Uemura, Yukari, Tsuchiya, Kiyoto, Matsushima, Tomoko, Noda, Kenta, Shimizu, Yosuke, Fujiwara, Asuka, Takamatsu, Yuki, Ichikawa, Yasuko, Nishimura, Hidehiro, Kinoshita, Mari, Matsumoto, Shota, Gatanaga, Hiroyuki, Yoshimura, Kazuhisa, Oka, Shin-ichi, Mikami, Ayako, Sugiura, Wataru, Sato, Toshiyuki, Yoshida, Tomokazu, Shimada, Shinya, Mitsuya, Hiroaki
Published in Scientific reports (24.11.2021)
Published in Scientific reports (24.11.2021)
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Journal Article
Molecular properties and regulation of NAD+ kinase (NADK)
Oka, Shin-ichi, Titus, Allen Sam, Zablocki, Daniela, Sadoshima, Junichi
Published in Redox biology (01.02.2023)
Published in Redox biology (01.02.2023)
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Journal Article
Hippo Deficiency Leads to Cardiac Dysfunction Accompanied by Cardiomyocyte Dedifferentiation During Pressure Overload
Ikeda, Shohei, Mizushima, Wataru, Sciarretta, Sebastiano, Abdellatif, Maha, Zhai, Peiyong, Mukai, Risa, Fefelova, Nadezhda, Oka, Shin-ichi, Nakamura, Michinari, Del Re, Dominic P, Farrance, Iain, Park, Ji Yeon, Tian, Bin, Xie, Lai-Hua, Kumar, Mohit, Hsu, Chiao-Po, Sadayappan, Sakthivel, Shimokawa, Hiroaki, Lim, Dae-Sik, Sadoshima, Junichi
Published in Circulation research (18.01.2019)
Published in Circulation research (18.01.2019)
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Journal Article
YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases
Ikeda, Shohei, Nah, Jihoon, Shirakabe, Akihiro, Zhai, Peiyong, Oka, Shin-Ichi, Sciarretta, Sebastiano, Guan, Kun-Liang, Shimokawa, Hiroaki, Sadoshima, Junichi
Published in The Journal of clinical investigation (01.03.2021)
Published in The Journal of clinical investigation (01.03.2021)
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Journal Article
Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart
Warren, Junco S., Tracy, Christopher M., Miller, Mickey R., Makaju, Aman, Szulik, Marta W., Oka, Shin-ichi, Yuzyuk, Tatiana N., Cox, James E., Kumar, Anil, Lozier, Bucky K., Wang, Li, Llana, June García, Sabry, Amira D., Cawley, Keiko M., Barton, Dane W., Han, Yong Hwan, Boudina, Sihem, Fiehn, Oliver, Tucker, Haley O., Zaitsev, Alexey V., Franklin, Sarah
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2018)
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Journal Article
Nampt Potentiates Antioxidant Defense in Diabetic Cardiomyopathy
Oka, Shin-ichi, Byun, Jaemin, Huang, Chun-yang, Imai, Nobushige, Ralda, Guersom, Zhai, Peiyong, Xu, Xiaoyong, Kashyap, Sanchita, Warren, Junco S., Alan Maschek, John, Tippetts, Trevor S., Tong, Mingming, Venkatesh, Sundararajan, Ikeda, Yoshiyuki, Mizushima, Wataru, Kashihara, Toshihide, Sadoshima, Junichi
Published in Circulation research (25.06.2021)
Published in Circulation research (25.06.2021)
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Journal Article
Both gain and loss of Nampt function promote pressure overload-induced heart failure
Byun, Jaemin, Oka, Shin-Ichi, Imai, Nobushige, Huang, Chun-Yang, Ralda, Guersom, Zhai, Peiyong, Ikeda, Yoshiyuki, Ikeda, Shohei, Sadoshima, Junichi
Published in American journal of physiology. Heart and circulatory physiology (01.10.2019)
Published in American journal of physiology. Heart and circulatory physiology (01.10.2019)
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Journal Article
Thioredoxin 1 promotes autophagy through transnitrosylation of Atg7 during myocardial ischemia
Nagarajan, Narayani, Oka, Shin-Ichi, Nah, Jihoon, Wu, Changgong, Zhai, Peiyong, Mukai, Risa, Xu, Xiaoyong, Kashyap, Sanchita, Huang, Chun-Yang, Sung, Eun-Ah, Mizushima, Wataru, Titus, Allen Sam, Takayama, Koichiro, Mourad, Youssef, Francisco, Jamie, Liu, Tong, Chen, Tong, Li, Hong, Sadoshima, Junichi
Published in The Journal of clinical investigation (01.02.2023)
Published in The Journal of clinical investigation (01.02.2023)
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Journal Article
Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes
Oka, Shin-ichi, Hirata, Tsuyoshi, Suzuki, Wataru, Naito, Daichi, Chen, Yanbin, Chin, Adave, Yaginuma, Hiroaki, Saito, Toshiro, Nagarajan, Narayani, Zhai, Peiyong, Bhat, Santosh, Schesing, Kevin, Shao, Dan, Hirabayashi, Yoko, Yodoi, Junji, Sciarretta, Sebastiano, Sadoshima, Junichi
Published in The Journal of biological chemistry (17.11.2017)
Published in The Journal of biological chemistry (17.11.2017)
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Journal Article
Multiple Levels of PGC-1α Dysregulation in Heart Failure
Oka, Shin-Ichi, Sabry, Amira D, Cawley, Keiko M, Warren, Junco S
Published in Frontiers in cardiovascular medicine (30.01.2020)
Published in Frontiers in cardiovascular medicine (30.01.2020)
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Journal Article
An Ideal PPAR Response Element Bound to and Activated by PPARα
Tzeng, John, Byun, Jaemin, Park, Ji Yeon, Yamamoto, Takanobu, Schesing, Kevin, Tian, Bin, Sadoshima, Junichi, Oka, Shin-Ichi
Published in PloS one (04.08.2015)
Published in PloS one (04.08.2015)
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Journal Article
PERM1 regulates genes involved in fatty acid metabolism in the heart by interacting with PPARα and PGC-1α
Huang, Chun-yang, Oka, Shin-ichi, Xu, Xiaoyong, Chen, Chian-Feng, Tung, Chien-Yi, Chang, Ya-Yuan, Mourad, Youssef, Vehra, Omair, Ivessa, Andreas, Yehia, Ghassan, Romanienko, Peter, Hsu, Chiao-Po, Sadoshima, Junichi
Published in Scientific reports (26.08.2022)
Published in Scientific reports (26.08.2022)
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Journal Article
Redox Regulatory Mechanism of Transnitrosylation by Thioredoxin
Wu, Changgong, Liu, Tong, Chen, Wei, Oka, Shin-ichi, Fu, Cexiong, Jain, Mohit Raja, Parrott, Andrew Myles, Baykal, Ahmet Tarik, Sadoshima, Junichi, Li, Hong
Published in Molecular & cellular proteomics (01.10.2010)
Published in Molecular & cellular proteomics (01.10.2010)
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Journal Article
Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1
Oka, Shin-Ichi, Sabry, Amira D, Horiuchi, Amanda K, Cawley, Keiko M, O'Very, Sean A, Zaitsev, Maria A, Shankar, Thirupura S, Byun, Jaemin, Mukai, Risa, Xu, Xiaoyong, Torres, Natalia S, Kumar, Anil, Yazawa, Masayuki, Ling, Jing, Taleb, Iosif, Saijoh, Yukio, Drakos, Stavros G, Sadoshima, Junichi, Warren, Junco S
Published in PloS one (23.06.2020)
Published in PloS one (23.06.2020)
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