Analysis of the Time-To-Onset and Factors Affecting Clinical Outcomes of Immune Reconstitution Inflammatory Syndrome in People Living with HIV Using Data from the Japanese Spontaneous Reporting Database
Tanaka, Hiroyuki, Wada, Tatsuhiko, Ohyama, Katsuhiro Ohyama, Ishii, Toshihiro
Published in Journal of pharmacy & pharmaceutical sciences (2021)
Published in Journal of pharmacy & pharmaceutical sciences (2021)
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Journal Article
Plasma and Hepatic Exposures of Celecoxib and Diclofenac Prescribed Alone in Patients with Cytochrome P450 2C93 Modeled after Virtual Oral Administrations and Likely Associated with Adverse Drug Events Reported in a Japanese Database
Adachi, Koichiro, Ohyama, Katsuhiro, Tanaka, Yoichi, Nakano, Hina, Sato, Tasuku, Murayama, Norie, Shimizu, Makiko, Saito, Yoshiro, Yamazaki, Hiroshi
Published in Biological & pharmaceutical bulletin (01.06.2023)
Published in Biological & pharmaceutical bulletin (01.06.2023)
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Journal Article
Pharmacovigilance study of the association between dipeptidyl peptidase–4 inhibitors and angioedema using the FDA Adverse Event Reporting System (FAERS)
Ohyama, Katsuhiro, Shindo, Junichiro, Takahashi, Tomohiro, Takeuchi, Hironori, Hori, Yusuke
Published in Scientific reports (30.07.2022)
Published in Scientific reports (30.07.2022)
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Modeled Hepatic/Plasma Exposures of Fluvastatin Prescribed Alone in Subjects with Impaired Cytochrome P450 2C93 as One of Possible Determinant Factors Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database
Adachi, Koichiro, Ohyama, Katsuhiro, Tanaka, Yoichi, Saito, Yoshiro, Shimizu, Makiko, Yamazaki, Hiroshi
Published in Biological & pharmaceutical bulletin (15.03.2024)
Published in Biological & pharmaceutical bulletin (15.03.2024)
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Journal Article
Modeled Hepatic/Plasma Exposures of Omeprazole Prescribed Alone in Cytochrome P450 2C19 Poor Metabolizers Are Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database
Adachi, Koichiro, Ohyama, Katsuhiro, Tanaka, Yoichi, Murayama, Norie, Shimizu, Makiko, Saito, Yoshiro, Yamazaki, Hiroshi
Published in Biological & pharmaceutical bulletin (24.05.2024)
Published in Biological & pharmaceutical bulletin (24.05.2024)
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Journal Article
Cytochrome P450-depedent Drug Oxidation Activity of Liver Microsomes from Microminipigs, A Possible New Animal Model for Humans in Non-clinical Studies
Murayama, Norie, Kaneko, Naoki, Horiuchi, Kana, Ohyama, Katsuhiro, Shimizu, Makiko, Ito, Katzuhiko, Yamazaki, Hiroshi
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2009)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2009)
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Roles of NADPH-P450 Reductase and Apo- and Holo-Cytochrome b5 on Xenobiotic Oxidations Catalyzed by 12 Recombinant Human Cytochrome P450s Expressed in Membranes of Escherichia coli
Yamazaki, Hiroshi, Nakamura, Mami, Komatsu, Tomoko, Ohyama, Katsuhiro, Hatanaka, Naoya, Asahi, Satoru, Shimada, Noriaki, Guengerich, F.Peter, Shimada, Tsutomu, Nakajima, Miki, Yokoi, Tsuyoshi
Published in Protein expression and purification (01.04.2002)
Published in Protein expression and purification (01.04.2002)
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A Significant Role of Human Cytochrome P450 2C8 in Amiodarone N-Deethylation: An Approach to Predict the Contribution with Relative Activity Factor
OHYAMA, Katsuhiro, NAKAJIMA, Miki, NAKAMURA, Sumika, SHIMADA, Noriaki, YAMAZAKI, Hiroshi, YOKOI, Tsuyoshi
Published in Drug metabolism and disposition (01.11.2000)
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Published in Drug metabolism and disposition (01.11.2000)
Journal Article
Pharmacokinetic Models Scaled Up from Humanized Liver Mouse Data Can Account for Drug Monitoring Results of Atomoxetine and Its 4-Hydroxylated and N -Demethylated Metabolites in Pediatric Patients Genotyped for Cytochrome P450 2D6
Shimizu, Makiko, Uehara, Shotaro, Ohyama, Katsuhiro, Nishimura, Haruka, Tanaka, Yoichi, Saito, Yoshiro, Suemizu, Hiroshi, Yoshida, Sayaka, Yamazaki, Hiroshi
Published in Drug metabolism and disposition (01.01.2024)
Published in Drug metabolism and disposition (01.01.2024)
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Journal Article
High hepatic and plasma exposures of atorvastatin in subjects harboring impaired cytochrome P450 3A4∗16 modeled after virtual administrations and possibly associated with statin intolerance found in the Japanese adverse drug event report database
Adachi, Koichiro, Ohyama, Katsuhiro, Tanaka, Yoichi, Sato, Tasuku, Murayama, Norie, Shimizu, Makiko, Saito, Yoshiro, Yamazaki, Hiroshi
Published in Drug metabolism and pharmacokinetics (01.04.2023)
Published in Drug metabolism and pharmacokinetics (01.04.2023)
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Journal Article
Association of gynecomastia with antidiabetic medications in older adults: Data mining from different national pharmacovigilance databases
Ohyama, Katsuhiro, Tanaka, Hiroyuki, Shindo, Junichiro, Shibayama, Manami, Iwata, Maya, Hori, Yusuke
Published in International journal of clinical pharmacology and therapeutics (01.01.2022)
Published in International journal of clinical pharmacology and therapeutics (01.01.2022)
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