Points to Consider in Continuous Manufacturing of Biotechnological Products
OKUDAIRA, Shinichi, SAKURAI, Kyoko, TAKEDA, Hiroshi, MATSUDA, Yoshihiro, TAKARADA, Tetsuhito, KONDO, Kohei, TAKAHASHI, Masabumi, ISHII, Ryusei, UCHIDA, Kazuhisa, LEE, In EUI, WADA, Kazuyo, KOBAYASHI, Yuki, SHIMIZU, Rie, KATO, Yasubumi, KURASHIMA, Hideki, HATAYAMA, Katsuhiro, OHDA, Toyoo, TORIKAI, Yusuke, KARIYA, Kinya, TSUKAMOTO, Jiro, OKURA, Hiroya, WATANABE, Naoto, MURAI, Kastushi, HARIGANEYA, Naohito, HIRASAWA, Ryutaro, HONGO, Tomoko, OYAMA, Kazunobu, TOKIEDA, Yoshiyuki, OTA, Yasumasa, SHIBATA, Mizuyo, SHINONAGA, Hideki, SHIBA, Yoichiro, SHIMIZU, Yoshiaki, YOSHINO, Takeshi, HORIUCHI, Takayuki, ISHIKAWA, Yoshimitsu, OE, Seigo, KAWASAKI, Tadayoshi, SHIBATA, Hiroko, HYUGA, Masashi, HONDA, Shinya, YAMAMOTO, Shuichi, MURAKAMI, Sei, OMASA, Takeshi, ISHII-WATABE, Akiko
Published in PDA Journal of GMP and Validation in Japan (2021)
Published in PDA Journal of GMP and Validation in Japan (2021)
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Journal Article
Development of a fed-batch culture process for enhanced production of recombinant human antithrombin by Chinese hamster ovary cells
Kuwae, Shinobu, Ohda, Toyoo, Tamashima, Hiroshi, Miki, Hideo, Kobayashi, Kaoru
Published in Journal of bioscience and bioengineering (01.11.2005)
Published in Journal of bioscience and bioengineering (01.11.2005)
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Journal Article
High level secretion of recombinant human serum albumin by fed-batch fermentation of the methylotrophic yeast, Pichia pastoris, based on optimal methanol feeding strategy
Kobayashi, Kaoru, Kuwae, Shinobu, Ohya, Tomoshi, Ohda, Toyoo, Ohyama, Masao, Tomomitsu, Kenji
Published in Journal of bioscience and bioengineering (2000)
Published in Journal of bioscience and bioengineering (2000)
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Journal Article
バイオ医薬品の連続生産に関するPoints to Consider
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Published in 日本PDA学術誌 GMPとバリデーション (2021)
Published in 日本PDA学術誌 GMPとバリデーション (2021)
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Journal Article
High-level expression of recombinant human serum albumin from the methylotrophic yeast Pichia pastoris with minimal protease production and activation
Kobayashi, Kaoru, Kuwae, Shinobu, Ohya, Tomoshi, Ohda, Toyoo, Ohyama, Masao, Ohi, Hideyuki, Tomomitsu, Kenji, Ohmura, Takao
Published in Journal of bioscience and bioengineering (2000)
Published in Journal of bioscience and bioengineering (2000)
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Journal Article
Analysis of Pichia pastoris Components in Recombinant Human Serum Albumin by Immunological Assays and by HPLC with Pulsed Amperometric Detection
Ohtani, Wataru, Ohda, Toyoo, Sumi, Akinori, Kobayashi, Kaoru, Ohmura, Takao
Published in Analytical chemistry (Washington) (15.01.1998)
Published in Analytical chemistry (Washington) (15.01.1998)
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Journal Article
Addition of oleic acid increases expression of recombinant human serum albumin by the AOX2 promoter in Pichia pastoris
Kobayashi, Kaoru, Kuwae, Shinobu, Ohya, Tomoshi, Ohda, Toyoo, Ohyama, Masao, Tomomitsu, Kenji
Published in Journal of bioscience and bioengineering (2000)
Published in Journal of bioscience and bioengineering (2000)
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Journal Article
PROCESS FOR PRODUCING RECOMBINANT ANTITHROMBIN
KOBAYASHI, KAORU, OHDA, TOYOO, KONDOU, MASAHIDE, OHI, HIDEYUKI, HIROSE, MASAAKI, MOCHIZUKI, SHINOBU, TAMASHIMA, HIROSHI, MIYANO, KENMI, KUWAE, SHINOBU
Year of Publication 28.10.2004
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Year of Publication 28.10.2004
Patent
PROCESS FOR PRODUCING GLYCOPROTEIN
MIKI, HIDEO, KOBAYASHI, KAORU, OHDA, TOYOO, SUGA, KENICHI, KATAKURA, YOSHIO, KISHIMOTO, MICHIMASA, OMASA, TAKESHI
Year of Publication 10.01.2002
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Year of Publication 10.01.2002
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PROCESS FOR PRODUCING FOREIGN PROTEINS
KOBAYASHI, KAORU, OHDA, TOYOO, OHYA, TOMOSHI, UEMURA, YAHIRO, OHYAMA, MASAO, KUWAE, SHINOBU
Year of Publication 08.10.1998
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Year of Publication 08.10.1998
Patent
PROCESS FOR PRODUCING PROTEINS
KOBAYASHI, KAORU, OHMURA, TAKAO, OHDA, TOYOO, TOMOMITSU, KENJI, OHYA, TOMOSHI, KUWAE, SHINOBU
Year of Publication 02.05.1996
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Year of Publication 02.05.1996
Patent
PROCESS FOR PRODUCING HUMAN SERUM ALBUMIN
KOBAYASHI, KAORU, OHDA, TOYOO, TOMOMITSU, KENJI, OHYA, TOMOSHI, KUWAE, SHINOBU
Year of Publication 08.04.2008
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Year of Publication 08.04.2008
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PRODUCTION METHOD OF HETEROLOGOUS PROTEIN
KOBAYASHI, KAORU, OHDA, TOYOO, OHYA, TOMOSHI, UEMURA, YAHIRO, OHYAMA, MASAO, KUWAE, SHINOBU
Year of Publication 23.06.2009
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Year of Publication 23.06.2009
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METHOD FOR PRODUCING PROTEIN
KOBAYASHI, KAORU, OHMURA, TAKAO, OHDA, TOYOO, TOMOMITSU, KENJI, OHYA, TOMOSHI, KUWAE, SHINOBU
Year of Publication 27.01.2009
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Year of Publication 27.01.2009
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Verfahren zur Herstellung von Protein
KOBAYASHI, KAORU, OHMURA, TAKAO, OHDA, TOYOO, TOMOMITSU, KENJI, OHYA, TOMOSHI, KUWAE, SHINOBU
Year of Publication 10.04.2008
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Year of Publication 10.04.2008
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PROCESS FOR PRODUCING PROTEINS
KOBAYASHI, KAORU, OHMURA, TAKAO, OHDA, TOYOO, TOMOMITSU, KENJI, OHYA, TOMOSHI, KUWAE, SHINOBU
Year of Publication 29.08.2007
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Year of Publication 29.08.2007
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Process for producing glycoprotein
KATAKURA YOSHIO, KISHIMOTO MICHIMASA, OHDA TOYOO, MIKI HIDEO, SUGA KENICHI, OMASA TAKESHI, KOBAYASHI KAORU
Year of Publication 21.06.2007
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Year of Publication 21.06.2007
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VERFAHREN ZUR HERSTELLUNG VON FREMDEN PROTEINEN
KUWAE,SHINOBU, KOBAYASHI, KAORU, OHDA, TOYOO, OHYA, TOMOSHI, UEMURA, YAHIRO, OHYAMA, MASAO
Year of Publication 06.07.2006
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Year of Publication 06.07.2006
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Process for producing human serum albumin
KOBAYASHI, KAORU, OHDA, TOYOO, TOMOMITSU, KENJI, OHYA, TOMOSHI, KUWAE, SHINOBU
Year of Publication 31.07.2002
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Year of Publication 31.07.2002
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