Potent and Selective Cathepsin L Inhibitors Do Not Inhibit Human Osteoclast Resorption in Vitro
James, Ian E., Marquis, Robert W., Blake, Simon M., Hwang, Shing Mei, Gress, Catherine J., Ru, Yu, Zembryki, Denise, Yamashita, Dennis S., McQueney, Michael S., Tomaszek, Thaddeus A., Oh, Hye-Ja, Gowen, Maxine, Veber, Daniel F., Lark, Michael W.
Published in The Journal of biological chemistry (13.04.2001)
Published in The Journal of biological chemistry (13.04.2001)
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Structure Activity Relationships of 5-, 6-, and 7-Methyl-Substituted Azepan-3-one Cathepsin K Inhibitors
Yamashita, Dennis S, Marquis, Robert W, Xie, Ren, Nidamarthy, Sirishkumar D, Oh, Hye-Ja, Jeong, Jae U, Erhard, Karl F, Ward, Keith W, Roethke, Theresa J, Smith, Brian R, Cheng, H-Y, Geng, Xiaoliu, Lin, Fan, Offen, Priscilla H, Wang, Bing, Nevins, Neysa, Head, Martha S, Haltiwanger, R. Curtis, Narducci Sarjeant, Amy A, Liable-Sands, Louise M, Zhao, Baoguang, Smith, Ward W, Janson, Cheryl A, Gao, Enoch, Tomaszek, Thaddeus, McQueney, Michael, James, Ian E, Gress, Catherine J, Zembryki, Denise L, Lark, Michael W, Veber, Daniel F
Published in Journal of medicinal chemistry (09.03.2006)
Published in Journal of medicinal chemistry (09.03.2006)
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The discovery of tertiary-amine LXR agonists with potent cholesterol efflux activity in macrophages
Marino, Joseph P., Kallander, Lara S., Ma, Chun, Oh, Hye-Ja, Lee, Dennis, Gaitanopoulos, Dimitri E., Krawiec, John A., Parks, Derek J., Webb, Christine L., Ziegler, Kelly, Jaye, Michael, Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Design, synthesis, and kinetic evaluation of high-affinity FKBP ligands and the X-ray crystal structures of their complexes with FKBP12
Holt, Dennis A, Luengo, Juan I, Yamashita, Dennis S, Oh, Hye Ja, Konialian, Arda L, Yen, Hwa Kwo, Rozamus, Leonard W, Brandt, Martin, Bossard, Mary J
Published in Journal of the American Chemical Society (01.11.1993)
Published in Journal of the American Chemical Society (01.11.1993)
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Structure-activity studies of synthetic FKBP ligands as peptidyl-prolyl isomerase inhibitors
Holt, Dennis A., Konialian-Beck, Arda L., Oh, Hye-Ja, Yen, Hwa-Kwo, Rozamus, Leonard W., Krog, Arnold J., Erhard, Karl F., Ortiz, Elizabeth, Levy, Mark A., Brandt, Martin, Bossard, Mary J., Luengo, Juan I.
Published in Bioorganic & medicinal chemistry letters (01.01.1994)
Published in Bioorganic & medicinal chemistry letters (01.01.1994)
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Discovery of Aminofurazan-azabenzimidazoles as Inhibitors of Rho-Kinase with High Kinase Selectivity and Antihypertensive Activity
Stavenger, Robert A, Cui, Haifeng, Dowdell, Sarah E, Franz, Robert G, Gaitanopoulos, Dimitri E, Goodman, Krista B, Hilfiker, Mark A, Ivy, Robert L, Leber, Jack D, Marino, Joseph P, Oh, Hye-Ja, Viet, Andrew Q, Xu, Weiwei, Ye, Guosen, Zhang, Daohua, Zhao, Yongdong, Jolivette, Larry J, Head, Martha S, Semus, Simon F, Elkins, Patricia A, Kirkpatrick, Robert B, Dul, Edward, Khandekar, Sanjay S, Yi, Tracey, Jung, David K, Wright, Lois L, Smith, Gary K, Behm, David J, Doe, Christopher P, Bentley, Ross, Chen, Zunxuan X, Hu, Erding, Lee, Dennis
Published in Journal of medicinal chemistry (11.01.2007)
Published in Journal of medicinal chemistry (11.01.2007)
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Inhibition of steroid 5α-reductase by unsaturated 3-carboxysteroids
HOLT, D. A, LEVY, M. A, HYE-JA OH, ERB, J. M, HEASLIP, J. I, BRANDT, M, HSUAN-YIN LAN-HARGEST, METCALF, B. W
Published in Journal of medicinal chemistry (01.03.1990)
Published in Journal of medicinal chemistry (01.03.1990)
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Steroidal a ring aryl carboxylic acids : a new class of steroid 5α-reductase inhibitors
HOLT, D. A, LEVY, M. A, LADD, D. L, HYE-JA OH, ERB, J. M, HEASLIP, J. I, BRANDT, M, METCALF, B. W
Published in Journal of medicinal chemistry (01.03.1990)
Published in Journal of medicinal chemistry (01.03.1990)
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Potent dipeptidylketone inhibitors of the cysteine protease cathepsin K
Marquis, Robert W, Ru, Yu, Yamashita, Dennis S, Oh, Hye-Ja, Yen, Jack, Thompson, Scott K, Carr, Thomas J, Levy, Mark A, Tomaszek, Thaddeus A, Ijames, Carl F, Smith, Ward W, Zhao, Baoguang, Janson, Cheryl A, Abdel-Meguid, Sherin S, D'Alessio, Karla J, McQueney, M.S, Veber, Daniel F
Published in Bioorganic & medicinal chemistry (01.04.1999)
Published in Bioorganic & medicinal chemistry (01.04.1999)
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Orally Active and Potent Inhibitors of γ-Aminobutyric Acid Uptake
Ali, Fadia E, Bondinell, William E, Dandridge, Penelope A, Frazee, James S, Garvey, Eleanor, Girard, Gerald R, Kaiser, Carl, Ku, Thomas W, Lafferty, John J, Moonsammy, George I, Oh, Hye-Ja, Rush, Julia A, Setler, Paulette E, Stringer, Orum D, Venslavsky, Joseph W, Volpe, Beth W, Yunger, Libby M, Zirkle, Charles L
Published in Journal of medicinal chemistry (01.05.1985)
Published in Journal of medicinal chemistry (01.05.1985)
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Use of Papain as a Model for the Structure-Based Design of Cathepsin K Inhibitors: Crystal Structures of Two Papain−Inhibitor Complexes Demonstrate Binding to S‘-Subsites
LaLonde, Judith M, Zhao, Baoguang, Smith, Ward W, Janson, Cheryl A, DesJarlais, Renee L, Tomaszek, Thaddeus A, Carr, Thomas J, Thompson, Scott K, Oh, Hye-Ja, Yamashita, Dennis S, Veber, Daniel F, Abdel-Meguid, Sherin S
Published in Journal of medicinal chemistry (05.11.1998)
Published in Journal of medicinal chemistry (05.11.1998)
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3-Phosphinic acid and 3-phosphonic acid steroids as inhibitors of steroid 5α-reductase: Species comparison and mechanistic studies
Levy, Mark A., Metcalf, Brian W., Brandt, Martin, Erb, Jill M., Oh, Hye-Ja, Heaslip, Julie I., Yen, Hwa-Kwo, Rozamus, Leonard W., Holt, Dennis A.
Published in Bioorganic chemistry (01.09.1991)
Published in Bioorganic chemistry (01.09.1991)
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3-Carboxy-20-keto steroids are dual uncompetitive inhibitors of human steroid 5α-reductase types 1 and 2
Yamashita, Dennis S., Holt, Dennis A., Oh, Hye-Ja, Shah, Dinu, Yen, Hwa-Kwo, Brandt, Martin, Levy, Mark A.
Published in Bioorganic & medicinal chemistry (01.09.1996)
Published in Bioorganic & medicinal chemistry (01.09.1996)
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6,7-Dichloro-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline. A structurally novel .beta.-adrenergic receptor blocking agent
Kaiser, Carl, Oh, Hye Ja, Garcia-Slanga, Blanche J, Sulpizio, Anthony C, Hieble, J. Paul, Wawro, Joyce E, Kruse, Lawrence I
Published in Journal of medicinal chemistry (01.11.1986)
Published in Journal of medicinal chemistry (01.11.1986)
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Design, synthesis and evaluation of dual domain FKBP ligands
Yamashita, Dennis S., Oh, Hye-Ja, Yen, Hwa-Kwo, Bossard, Mary J., Brandt, Martin, Levy, Mark A., Newman-Tarr, Tonie, Badger, Alison, Luengo, Juan I., Holt, Dennis A.
Published in Bioorganic & medicinal chemistry letters (20.01.1994)
Published in Bioorganic & medicinal chemistry letters (20.01.1994)
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6-(Phenylthio)-substituted 2,3,4,5-tetrahydro-1H-3-benzazepines, a novel class of dopamine receptor antagonists and neuroleptics
Kaiser, Carl, Ali, Fadia E, Bondinell, William E, Brenner, Martin, Holden, Kenneth G, Ku, Thomas W, Oh, Hye-Ja, Ross, Stephen T, Yim, Nelson C. F
Published in Journal of medicinal chemistry (01.09.1980)
Published in Journal of medicinal chemistry (01.09.1980)
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Synthesis and evaluation of 3-carboxymethyl steroids as inhibitors of human prostatic steroid 5α-reductase
Holt, Dennis A., Oh, Hye-Ja, Rozamus, Leonard W., Yen, Hwa-Kwo, Brandt, Martin, Levy, Mark A., Brian W., Metcalf
Published in Bioorganic & medicinal chemistry letters (01.08.1993)
Published in Bioorganic & medicinal chemistry letters (01.08.1993)
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