Pharmacokinetics Versus In Vitro Antiproliferative Potency to Design a Novel Hyperglycosylated hIFN-α2 Biobetter
Gugliotta, Agustina, Leopold, María Jesús, Mufarrege, Eduardo, Etcheverrigaray, Marina, Kratje, Ricardo, Ceaglio, Natalia, Oggero, Marcos
Published in Pharmaceutical research (2021)
Published in Pharmaceutical research (2021)
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Large Area Microfluidic Bioreactor for Production of Recombinant Protein
Bourguignon, Natalia, Karp, Paola, Attallah, Carolina, Chamorro, Daniel A., Oggero, Marcos, Booth, Ross, Ferrero, Sol, Bhansali, Shekhar, Pérez, Maximiliano S., Lerner, Betiana, Helguera, Gustavo
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Published in Biosensors (Basel) (14.07.2022)
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Neuroprotective activity of a new erythropoietin formulation with increased penetration in the central nervous system
Etcheverrigaray, Marina, Ceaglio, Natalia, Mattio, Mónica, Oggero, Marcos, Amadeo, Ignacio, Forno, Guillermina, Perotti, Norma, Kratje, Ricardo
Published in BMC proceedings (22.11.2011)
Published in BMC proceedings (22.11.2011)
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A highly efficient modified human serum albumin signal peptide to secrete proteins in cells derived from different mammalian species
Attallah, Carolina, Etcheverrigaray, Marina, Kratje, Ricardo, Oggero, Marcos
Published in Protein expression and purification (01.04.2017)
Published in Protein expression and purification (01.04.2017)
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Bifunctional GM-CSF-derived peptides as tools for O-glycoengineering and protein tagging
Sales, María de los Milagros, Kratje, Ricardo, Oggero, Marcos, Ceaglio, Natalia
Published in Journal of biotechnology (10.02.2021)
Published in Journal of biotechnology (10.02.2021)
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Journal Article
Pharmacokinetics Versus In Vitro Antiproliferative Potency to Design a Novel Hyperglycosylated hIFN-[alpha]2 Biobetter
Gugliotta, Agustina, Leopold, María Jesús, Mufarrege, Eduardo, Etcheverrigaray, Marina, Kratje, Ricardo, Ceaglio, Natalia, Oggero, Marcos
Published in Pharmaceutical research (01.01.2021)
Published in Pharmaceutical research (01.01.2021)
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Changes in antibody binding and functionality after humanizing a murine scFv anti-IFN-α2: From in silico studies to experimental analysis
Aguilar, María Fernanda, Garay, A. Sergio, Attallah, Carolina, Rodrigues, Daniel E., Oggero, Marcos
Published in Molecular immunology (01.11.2022)
Published in Molecular immunology (01.11.2022)
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Chemistry of polyhalogenated nitrobutadienes, 19: synthesis of new types of compounds modulating the biological activity of type I Interferons (IFN-I)
Zapol’skii, Viktor A., Bürgi, Milagros, Oggero, Marcos, Bollati-Fogolín, Mariela, Kaufmann, Dieter E.
Published in ARKIVOC free online journal of organic chemistry (03.05.2023)
Published in ARKIVOC free online journal of organic chemistry (03.05.2023)
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Development of highly stable and de-immunized versions of recombinant alpha interferon: Promising candidates for the treatment of chronic and emerging viral diseases
Giorgetti, Sofía Inés, Etcheverrigaray, Marina, Terry, Frances, Martin, William, De Groot, Anne Searls, Ceaglio, Natalia, Oggero, Marcos, Mufarrege, Eduardo Federico
Published in Clinical immunology (Orlando, Fla.) (01.12.2021)
Published in Clinical immunology (Orlando, Fla.) (01.12.2021)
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N‐ and O‐linked carbohydrates and glycosylation site occupancy in recombinant human granulocyte‐macrophage colony‐stimulating factor secreted by a Chinese hamster ovary cell line
Forno, Guillermina, Bollati Fogolin, Mariela, Oggero, Marcos, Kratje, Ricardo, Etcheverrigaray, Marina, Conradt, Harald S., Nimtz, Manfred
Published in European journal of biochemistry (01.03.2004)
Published in European journal of biochemistry (01.03.2004)
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Novel erythropoietin-based therapeutic candidates with extra N-glycan sites that block hematopoiesis but preserve neuroplasticity
Bürgi, Milagros, Aparicio, Gabriela Inés, Dorella, Aquiles, Kratje, Ricardo, Scorticati, Camila, Oggero, Marcos
Published in Biotechnology journal (01.05.2021)
Published in Biotechnology journal (01.05.2021)
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Glycosylation and antiproliferative activity of hyperglycosylated IFN-α2 potentiate HEK293 cells as biofactories
Gugliotta, Agustina, Ceaglio, Natalia, Raud, Brenda, Forno, Guillermina, Mauro, Laura, Kratje, Ricardo, Oggero, Marcos
Published in European journal of pharmaceutics and biopharmaceutics (01.03.2017)
Published in European journal of pharmaceutics and biopharmaceutics (01.03.2017)
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The glycosylation of anti-rhIFN-α2b recombinant antibodies influences the antigen-neutralizing activity
Attallah, Carolina, Aguilar, María Fernanda, Forno, Guillermina, Etcheverrigaray, Marina, Brigido, Marcelo De Macedo, Maranhão, Andrea Queiroz, Oggero, Marcos
Published in Biotechnology letters (01.08.2020)
Published in Biotechnology letters (01.08.2020)
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Design and validation of an immuno-PCR assay for IFN-α2b quantification in human plasma
Attallah, Carolina, Rodríguez, María C, Lozano, Victoria, Etcheverrigaray, Marina, Oggero, Marcos
Published in Bioanalysis (01.12.2019)
Published in Bioanalysis (01.12.2019)
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Improvement of in vitro stability and pharmacokinetics of hIFN-α by fusing the carboxyl-terminal peptide of hCG β-subunit
Ceaglio, Natalia, Gugliotta, Agustina, Tardivo, María Belén, Cravero, Dianela, Etcheverrigaray, Marina, Kratje, Ricardo, Oggero, Marcos
Published in Journal of biotechnology (10.03.2016)
Published in Journal of biotechnology (10.03.2016)
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Influence of carbohydrates on the stability and structure of a hyperglycosylated human interferon alpha mutein
Ceaglio, Natalia, Etcheverrigaray, Marina, Kratje, Ricardo, Oggero, Marcos
Published in Biochimie (01.08.2010)
Published in Biochimie (01.08.2010)
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