Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion
Pound, Lynley D, Sarkar, Suparna A, Benninger, Richard K P, Wang, Yingda, Suwanichkul, Adisak, Shadoan, Melanie K, Printz, Richard L, Oeser, James K, Lee, Catherine E, Piston, David W, McGuinness, Owen P, Hutton, John C, Powell, David R, O'Brien, Richard M
Published in Biochemical journal (15.07.2009)
Published in Biochemical journal (15.07.2009)
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Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion
Syring, Kristen E, Boortz, Kayla A, Oeser, James K, Ustione, Alessandro, Platt, Kenneth A, Shadoan, Melanie K, McGuinness, Owen P, Piston, David W, Powell, David R, O'Brien, Richard M
Published in Endocrinology (Philadelphia) (01.12.2016)
Published in Endocrinology (Philadelphia) (01.12.2016)
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G6PC2: A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion
POUND, Lynley D, OESER, James K, O'BRIEN, Richard M, O'BRIEN, Tracy P, YINGDA WANG, FAULMAN, Chandler J, DADI, Prasanna K, JACOBSON, David A, HUTTON, John C, MCGUINNESS, Owen P, SHIOTA, Masakazu
Published in Diabetes (New York, N.Y.) (01.05.2013)
Published in Diabetes (New York, N.Y.) (01.05.2013)
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Pancreatic islet beta cell-specific deletion of G6pc2 reduces fasting blood glucose
Bosma, Karin J, Rahim, Mohsin, Singh, Kritika, Goleva, Slavina B, Wall, Martha L, Xia, Jing, Syring, Kristen E, Oeser, James K, Poffenberger, Greg, McGuinness, Owen P, Means, Anna L, Powers, Alvin C, Li, Wen-hong, Davis, Lea K, Young, Jamey D, O’Brien, Richard M
Published in Journal of molecular endocrinology (01.05.2020)
Published in Journal of molecular endocrinology (01.05.2020)
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Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression
Boortz, Kayla A, Syring, Kristen E, Pound, Lynley D, Wang, Yingda, Oeser, James K, O'Brien, Richard M
Published in PloS one (09.09.2016)
Published in PloS one (09.09.2016)
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The Glucose-6-Phosphatase Catalytic Subunit Gene Promoter Contains Both Positive and Negative Glucocorticoid Response Elements
Vander Kooi, Beth T, Onuma, Hiroshi, Oeser, James K, Svitek, Christina A, Allen, Shelley R, Vander Kooi, Craig W, Chazin, Walter J, O’Brien, Richard M
Published in Molecular endocrinology (Baltimore, Md.) (01.12.2005)
Published in Molecular endocrinology (Baltimore, Md.) (01.12.2005)
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The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer
Pound, Lynley D, Hang, Yan, Sarkar, Suparna A, Wang, Yingda, Milam, Laurel A, Oeser, James K, Printz, Richard L, Lee, Catherine E, Stein, Roland, Hutton, John C, O'Brien, Richard M
Published in Biochemical journal (01.01.2011)
Published in Biochemical journal (01.01.2011)
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Correlation between FOXO1a (FKHR) and FOXO3a (FKHRL1) Binding and the Inhibition of Basal Glucose-6-Phosphatase Catalytic Subunit Gene Transcription by Insulin
Onuma, Hiroshi, Vander Kooi, Beth T, Boustead, Jared N, Oeser, James K, O’Brien, Richard M
Published in Molecular endocrinology (Baltimore, Md.) (01.11.2006)
Published in Molecular endocrinology (Baltimore, Md.) (01.11.2006)
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Characterization of the human SLC30A8 promoter and intronic enhancer
Pound, Lynley D, Sarkar, Suparna A, Cauchi, Stéphane, Wang, Yingda, Oeser, James K, Lee, Catherine E, Froguel, Philippe, Hutton, John C, O'Brien, Richard M
Published in Journal of molecular endocrinology (01.12.2011)
Published in Journal of molecular endocrinology (01.12.2011)
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G6PC1 and G6PC2 influence G6P flux but not HSD11B1 activity
Hawes, Emily M, Boortz, Kayla A, Oeser, James K, O'Rourke, Margaret L, O'Brien, Richard M
Published in Journal of molecular endocrinology (01.11.2023)
Published in Journal of molecular endocrinology (01.11.2023)
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Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose
Overway, Emily M., Bosma, Karin J., Claxton, Derek P., Oeser, James K., Singh, Kritika, Breidenbach, Lindsay B., Mchaourab, Hassane S., Davis, Lea K., O'Brien, Richard M.
Published in The Journal of biological chemistry (01.02.2022)
Published in The Journal of biological chemistry (01.02.2022)
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Biochemical and metabolic characterization of a G6PC2 inhibitor
Hawes, Emily M., Rahim, Mohsin, Haratipour, Zeinab, Orun, Abigail R., O'Rourke, Margaret L., Oeser, James K., Kim, Kwangho, Claxton, Derek P., Blind, Ray D., Young, Jamey D., O'Brien, Richard M.
Published in Biochimie (01.07.2024)
Published in Biochimie (01.07.2024)
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Long-Range Enhancers Are Required to Maintain Expression of the Autoantigen Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein in Adult Mouse Islets In Vivo
Wang, Yingda, Flemming, Brian P, Martin, Cyrus C, Allen, Shelley R, Walters, Jay, Oeser, James K, Hutton, John C, O'Brien, Richard M
Published in Diabetes (New York, N.Y.) (01.01.2008)
Published in Diabetes (New York, N.Y.) (01.01.2008)
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An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets
Keller, Mark P, Hawes, Emily M, Schueler, Kathryn L, Stapleton, Donnie S, Mitok, Kelly A, Simonett, Shane P, Oeser, James K, Sampson, Leesa L, Attie, Alan D, Magnuson, Mark A, O'Brien, Richard M
Published in Diabetes (New York, N.Y.) (01.11.2023)
Published in Diabetes (New York, N.Y.) (01.11.2023)
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Journal Article
The Three Insulin Response Sequences in the Glucose-6-phosphatase Catalytic Subunit Gene Promoter Are Functionally Distinct
Vander Kooi, Beth T, Streeper, Ryan S, Svitek, Christina A, Oeser, James K, Powell, David R, O'Brien, Richard M
Published in The Journal of biological chemistry (04.04.2003)
Published in The Journal of biological chemistry (04.04.2003)
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Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells
Rahim, Mohsin, Nakhe, Arya Y., Banerjee, Deveena R., Overway, Emily M., Bosma, Karin J., Rosch, Jonah C., Oeser, James K., Wang, Bo, Lippmann, Ethan S., Jacobson, David A., O'Brien, Richard M., Young, Jamey D.
Published in The Journal of biological chemistry (01.04.2022)
Published in The Journal of biological chemistry (01.04.2022)
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