P746: COMBINATION OF RAS/MAPK MODULATOR AND AZACITIDINE AFFECTS HISTONE MARKS AND IMPACTS THE INNATE IMMUNE SIGNALING PATHWAY IN THE MDS‐L CELL LINE
Rai, R., Patel, F., Feld, J., Melana, S., Navada, S., Odchimar‐Reissig, R., Demakos, E., Reddy, E. P., Horowitz, A., Silverman, L.
Published in HemaSphere (01.06.2022)
Published in HemaSphere (01.06.2022)
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Rigosertib in Combination with Azacitidine Modulates Epigenetic Pathways and can Overcome Clinical Resistance to Hypomethylating Agents in Myelodysplastic Syndromes (MDS)
Chaurasia, P, Isoda, F, Navada, S, Odchimar-Reissig, R, Demakos, E.P, Reddy, E.P, Silverman, L.R
Published in Leukemia research (01.04.2017)
Published in Leukemia research (01.04.2017)
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Combination of Oral Rigosertib and Injectable Azacitidine in Patients with Myelodysplastic Syndromes (MDS)
Navada, S, Garcia-Manero, G, Hearn, K, Odchimar-Reissig, R, Demakos, E, Fenaux, P, Petrone, M, Zbyszewski, P, Fruchtman, S, Silverman, L
Published in Leukemia research (01.04.2017)
Published in Leukemia research (01.04.2017)
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89 A PHASE I STUDY OF THE COMBINATION OF AZACITIDINE AND ORAL RIGOSERTIB IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES (MDS) OR ACUTE MYELOID LEUKEMIA (AML)
Navada, S.C, Garcia-Manero, G, Hearn, K, Odchimar-Reissig, R, Demakos, E, Alvarado, Y, Daver, N, DiNardo, C, Konopleva, M, Borthakur, G, Azarnia, N, Silverman, L.R
Published in Leukemia research (01.04.2015)
Published in Leukemia research (01.04.2015)
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Journal Article
P-274 Rigosertib activity in patients with a myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) relapsed or refractory to hypomethylating agents
Navada, S.C, Odchimar-Reissig, R, Reddy, E.P, Demakos, E.P, Holland, J.F, Wilhelm, F, Silverman, L.R
Published in Leukemia research (01.05.2013)
Published in Leukemia research (01.05.2013)
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P131 Phase I trial of the combination of the epigenetic modulators vorinostat and azacitidine (azaC) in patients with the myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). An update from the NY Cancer Consortium
Silverman, L, Verma, A, Odchimar-Reissig, R, LeBlane, A, Najfeld, V, Gabrilove, J, Isola, L, Espinoza-Delgado, I, Zwiebel, J
Published in Leukemia research (01.05.2009)
Published in Leukemia research (01.05.2009)
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P26 - Topic: AS04-MDS Biology and Pathogenesis/AS04f-Gene expression profiling: THE COMBINATION OF A RAS SIGNALING MODULATOR WITH AZACITIDINE IMPROVES HEMATOPOIESIS IN VIVO AND HAS IN VITRO EFFECTS ON METABOLIC/DIFFERENTIATION PATHWAYS AND INNATE IMMUNE SIGNALING
Rai, R., Patel, F., Melana, S., Feld, J., Navada, S., Odchimar-Reissig, R., Demakos, E., Reddy, E.P., Silverman, L.
Published in Leukemia research (01.09.2021)
Published in Leukemia research (01.09.2021)
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Journal Article
Topic: AS04-MDS Biology and Pathogenesis/AS04f-Gene expression profiling
Rai, R., Patel, F., Melana, S., Feld, J., Navada, S., Odchimar-Reissig, R., Demakos, E., Reddy, E.P., Silverman, L.
Published in Leukemia research (01.09.2021)
Published in Leukemia research (01.09.2021)
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Journal Article
204 - Rigosertib in Combination with Azacitidine Modulates Epigenetic Pathways and can Overcome Clinical Resistance to Hypomethylating Agents in Myelodysplastic Syndromes (MDS)
Chaurasia, P., Isoda, F., Navada, S., Odchimar-Reissig, R., Demakos, E.P., Reddy, E.P., Silverman, L.R.
Published in Leukemia research (01.04.2017)
Published in Leukemia research (01.04.2017)
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Journal Article
Randomized Controlled Trial of Azacitidine in Patients With the Myelodysplastic Syndrome: A Study of the Cancer and Leukemia Group B
SILVERMAN, Lewis R, DEMAKOS, Erin P, ELLERTON, John, LARSON, Richard A, SCHIFFER, Charles A, HOLLAND, James F, PETERSON, Bercedis L, KORNBLITH, Alice B, HOLLAND, Jimmie C, ODCHIMAR-REISSIG, Rosalie, STONE, Richard M, NELSON, Douglas, POWELL, Bayard L, DECASTRO, Carlos M
Published in Journal of clinical oncology (15.05.2002)
Published in Journal of clinical oncology (15.05.2002)
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PS1332 RIGOSERTIB MODULATES HEMATOPOIESIS GENE SIGNALING PATHWAYS ALONE OR IN SEQUENCED COMBINATION WITH AZACTIDINE ON MDS CELLS IN VITRO
Rai, R., Melana, S., Navada, S.C., Odchimar‐Reissig, R., Demakos, E.P., Reddy, E.P., Silverman, L.R.
Published in HemaSphere (01.06.2019)
Published in HemaSphere (01.06.2019)
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Journal Article
43 - Combination of Oral Rigosertib and Injectable Azacitidine in Patients with Myelodysplastic Syndromes (MDS)
Navada, S., Garcia-Manero, G., Hearn, K., Odchimar-Reissig, R., Demakos, E., Fenaux, P., Petrone, M., Zbyszewski, P., Fruchtman, S., Silverman, L.
Published in Leukemia research (01.04.2017)
Published in Leukemia research (01.04.2017)
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Impact of Azacytidine on the Quality of Life of Patients With Myelodysplastic Syndrome Treated in a Randomized Phase III Trial: A Cancer and Leukemia Group B Study
KORNBLITH, Alice B, HERNDON, James E, SCHIFFER, Charles A, HOLLAND, Jimmie C, SILVERMAN, Lewis R, DEMAKOS, Erin P, ODCHIMAR-REISSIG, Rosalie, HOLLAND, James F, POWELL, Bayard L, DECASTRO, Carlos, ELLERTON, John, LARSON, Richard A
Published in Journal of clinical oncology (15.05.2002)
Published in Journal of clinical oncology (15.05.2002)
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Journal Article
S839 PHASE II STUDY OF ORAL RIGOSERTIB COMBINED WITH AZACITIDINE IN PATIENTS WITH HIGHER‐RISK MYELODYSPLASTIC SYNDROMES (MDS)
Navada, S.C., Garcia‐Manero, G., Atallah, E., Rajeh, M.N., Shammo, J.M., Griffiths, E.A., Khaled, S.K., Dakhil, S.R., Young, D.E., Odchimar‐Reissig, R., Demakos, E.P., Alvarado Valero, Y., Ohanian, M.N., Pemmaraju, N., John, R.B., Zbyszewski, P.S., Maniar, M., Petrone, M.E., Woodman, R.C., Fruchtman, S.M., Silverman, L.R.
Published in HemaSphere (01.06.2019)
Published in HemaSphere (01.06.2019)
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Journal Article
A phase I/II study of vorinostat, an oral histone deacetylase inhibitor, in combination with azacitidine in patients with the myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Initial results of the phase I trial: A New York Cancer Consortium
Silverman, L. R., Verma, A., Odchimar-Reissig, R., Cozza, A., Najfeld, V., Licht, J. D., Zwiebel, J. A.
Published in Journal of clinical oncology (20.05.2008)
Published in Journal of clinical oncology (20.05.2008)
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