Mechanism-based approaches to treating fragile X
Dölen, Gül, Carpenter, Randall L, Ocain, Timothy D, Bear, Mark F
Published in Pharmacology & therapeutics (Oxford) (01.07.2010)
Published in Pharmacology & therapeutics (Oxford) (01.07.2010)
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Substrate-Based Design of the First Class of Angiotensin-Converting Enzyme-Related Carboxypeptidase (ACE2) Inhibitors
Dales, Natalie A, Gould, Alexandra E, Brown, James A, Calderwood, Emily F, Guan, Bing, Minor, Charles A, Gavin, James M, Hales, Paul, Kaushik, Virendar K, Stewart, Michael, Tummino, Peter J, Vickers, Chad S, Ocain, Timothy D, Patane, Michael A
Published in Journal of the American Chemical Society (09.10.2002)
Published in Journal of the American Chemical Society (09.10.2002)
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Participation of Rip2 in Lipopolysaccharide Signaling Is Independent of Its Kinase Activity
Lu, Chafen, Wang, Anlai, Dorsch, Marion, Tian, Jane, Nagashima, Kumiko, Coyle, Anthony J., Jaffee, Bruce, Ocain, Timothy D., Xu, Yajun
Published in The Journal of biological chemistry (22.04.2005)
Published in The Journal of biological chemistry (22.04.2005)
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Design, Synthesis, and Evaluation of Naphthalene-Sulfonamide Antagonists of Human CCR8
Jenkins, Tracy J, Guan, Bing, Dai, Mingshi, Li, Gang, Lightburn, Thomas E, Huang, Shan, Freeze, B. Scott, Burdi, Douglas F, Jacutin-Porte, Swanee, Bennett, Robert, Chen, Weirong, Minor, Charles, Ghosh, Shomir, Blackburn, Christopher, Gigstad, Kenneth M, Jones, Matthew, Kolbeck, Roland, Yin, Wei, Smith, Sean, Cardillo, Daniel, Ocain, Timothy D, Harriman, Geraldine C
Published in Journal of medicinal chemistry (08.02.2007)
Published in Journal of medicinal chemistry (08.02.2007)
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Novel Small-Molecule Inhibitors of RNA Polymerase III
Wu, Liping, Pan, Jing, Thoroddsen, Vala, Wysong, Deborah R, Blackman, Ronald K, Bulawa, Christine E, Gould, Alexandra E, Ocain, Timothy D, Dick, Lawrence R, Errada, Patrick, Dorr, Patrick K, Parkinson, Tanya, Wood, Tony, Kornitzer, Daniel, Weissman, Ziva, Willis, Ian M, McGovern, Karen
Published in Eukaryotic Cell (01.04.2003)
Published in Eukaryotic Cell (01.04.2003)
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Regulation of IRAK-4 kinase activity via autophosphorylation within its activation loop
Cheng, Hong, Addona, Terri, Keshishian, Hasmik, Dahlstrand, Erik, Lu, Chafen, Dorsch, Marion, Li, Zhi, Wang, Anlai, Ocain, Timothy D., Li, Ping, Parsons, Thomas F., Jaffee, Bruce, Xu, Yajun
Published in Biochemical and biophysical research communications (19.01.2007)
Published in Biochemical and biophysical research communications (19.01.2007)
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Nucleotide binding to CARD12 and its role in CARD12-mediated caspase-1 activation
Lu, Chafen, Wang, Anlai, Wang, Lin, Dorsch, Marion, Ocain, Timothy D., Xu, Yajun
Published in Biochemical and biophysical research communications (17.06.2005)
Published in Biochemical and biophysical research communications (17.06.2005)
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T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: the molecular basis of negative selection
Clayton, Linda K., Ghendler, Yoseph, Mizoguchi, Emiko, Patch, Raymond J., Ocain, Timothy D., Orth, Kim, Bhan, Atul K., Dixit, Vishva M., Reinherz, Ellis L.
Published in The EMBO Journal (01.05.1997)
Published in The EMBO Journal (01.05.1997)
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Pharmacological characterization of guinea pig chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)
Liu, Fang, Gonzalo, Jose Angel, Manning, Stephen, O’Connell, Laura E., Fedyk, Eric R., Burke, Kristine E., Elder, Amy M., Pulido, Jacqueline C., Cao, Wei, Tayber, Olga, Qiu, Yubin, Ghosh, Shomir, Ocain, Timothy D., Hodge, Martin R., Suzuki-Yagawa, Yuriko
Published in Prostaglandins & other lipid mediators (01.05.2005)
Published in Prostaglandins & other lipid mediators (01.05.2005)
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Synthesis and immunosuppressive activity of ruthenium complexes
Bastos, Cecilia M., Gordon, Kristin A., Ocain, Timothy D.
Published in Bioorganic & medicinal chemistry letters (20.01.1998)
Published in Bioorganic & medicinal chemistry letters (20.01.1998)
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Conformationally defined analogs of prolylamides. trans-Prolyl peptidomimetics
Andres, Charles J, Macdonald, Timothy L, Ocain, Timothy D, Longhi, Daniel
Published in Journal of organic chemistry (01.11.1993)
Published in Journal of organic chemistry (01.11.1993)
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Journal Article
A Selective Small Molecule IκB Kinase β Inhibitor Blocks Nuclear Factor κB-Mediated Inflammatory Responses in Human Fibroblast-Like Synoviocytes, Chondrocytes, and Mast Cells
Wen, Danyi, Nong, Yuhua, Morgan, Jennifer G., Gangurde, Pranoti, Bielecki, Andrew, DaSilva, Jennifer, Keaveney, Marie, Cheng, Hong, Fraser, Chris, Schopf, Lisa, Hepperle, Michael, Harriman, Geraldine, Jaffee, Bruce D., Ocain, Timothy D., Xu, Yajun
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
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New modified heterocyclic phenylalanine derivatives. Incorporation into potent inhibitors of human renin
Ocain, Timothy D, Deininger, David D, Russo, Ralph, Senko, Nancie A, Katz, Alan, Kitzen, Jan M, Mitchell, Robert, Oshiro, George, Russo, Anthony
Published in Journal of medicinal chemistry (01.03.1992)
Published in Journal of medicinal chemistry (01.03.1992)
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Journal Article
Amino acid derived latent isocyanates: irreversible inactivation of porcine pancreatic elastase and human leukocyte elastase
Groutas, William C, Abrams, William R, Theodorakis, Michael C, Kasper, Annette M, Rude, Steven A, Badger, Robert C, Ocain, Timothy D, Miller, Kevin E, Moi, Min K
Published in Journal of medicinal chemistry (01.02.1985)
Published in Journal of medicinal chemistry (01.02.1985)
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Journal Article
A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells
Wen, Danyi, Nong, Yuhua, Morgan, Jennifer G, Gangurde, Pranoti, Bielecki, Andrew, Dasilva, Jennifer, Keaveney, Marie, Cheng, Hong, Fraser, Chris, Schopf, Lisa, Hepperle, Michael, Harriman, Geraldine, Jaffee, Bruce D, Ocain, Timothy D, Xu, Yajun
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
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Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
Journal Article
A Selective Small Molecule IκB Kinase β Inhibitor Blocks Nuclear Factor κB-Mediated Inflammatory Responses in Human Fibroblast-Like Synoviocytes, Chondrocytes, and Mast Cells
Danyi Wen, Yuhua Nong, Jennifer G. Morgan, Pranoti Gangurde, Andrew Bielecki, Jennifer DaSilva, Marie Keaveney, Hong Cheng, Chris Fraser, Lisa Schopf, Michael Hepperle, Geraldine Harriman, Bruce D. Jaffee, Timothy D. Ocain, Yajun Xu
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
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