Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy
Mahameed, Mohamed, Boukeileh, Shatha, Obiedat, Akram, Darawshi, Odai, Dipta, Priya, Rimon, Amit, McLennan, Gordon, Fassler, Rosi, Reichmann, Dana, Karni, Rotem, Preisinger, Christian, Wilhelm, Thomas, Huber, Michael, Tirosh, Boaz
Published in Nature communications (11.03.2020)
Published in Nature communications (11.03.2020)
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Journal Article
The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors
Mahameed, Mohamed, Wilhelm, Thomas, Darawshi, Odai, Obiedat, Akram, Tommy, Weiss-Sadan, Chintha, Chetan, Schubert, Thomas, Samali, Afshin, Chevet, Eric, Eriksson, Leif A., Huber, Michael, Tirosh, Boaz
Published in Cell death & disease (01.04.2019)
Published in Cell death & disease (01.04.2019)
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Journal Article
The integrated stress response promotes B7H6 expression
Obiedat, Akram, Charpak-Amikam, Yoav, Tai-Schmiedel, Julie, Seidel, Einat, Mahameed, Mohamed, Avril, Tony, Stern-Ginossar, Noam, Springuel, Lorraine, Bolsée, Jennifer, Gilham, David E., Dipta, Priya, Shmuel, Miriam, Chevet, Eric, Mandelboim, Ofer, Tirosh, Boaz
Published in Journal of molecular medicine (Berlin, Germany) (01.01.2020)
Published in Journal of molecular medicine (Berlin, Germany) (01.01.2020)
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Journal Article
Mnk2 Alternative Splicing Modulates the p38-MAPK Pathway and Impacts Ras-Induced Transformation
Maimon, Avraham, Mogilevsky, Maxim, Shilo, Asaf, Golan-Gerstl, Regina, Obiedat, Akram, Ben-Hur, Vered, Lebenthal-Loinger, Ilana, Stein, Ilan, Reich, Reuven, Beenstock, Jonah, Zehorai, Eldar, Andersen, Claus L., Thorsen, Kasper, Ørntoft, Torben F., Davis, Roger J., Davidson, Ben, Mu, David, Karni, Rotem
Published in Cell reports (Cambridge) (01.04.2014)
Published in Cell reports (Cambridge) (01.04.2014)
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Journal Article
254 NTX-1088, a potent anti-PVR Mab induces DNAM1-mediated antitumor immunity
Atieh, Anas, Obiedat, Akram, Cinamon, Guy, Rovis, Tihana Lenac, Brlic, Paola Kucan, Hirsl, Lea, Mandelboim, Ofer, Jonjic, Stipan, Paz, Keren, Tsukerman, Pini
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1
Obiedat, Akram, Seidel, Einat, Mahameed, Mohamed, Berhani, Orit, Tsukerman, Pinchas, Voutetakis, Konstantinos, Chatziioannou, Aristotelis, McMahon, Mari, Avril, Tony, Chevet, Eric, Mandelboim, Ofer, Tirosh, Boaz
Published in The FASEB journal (01.03.2019)
Published in The FASEB journal (01.03.2019)
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Journal Article
IRE1 endoribonuclease signaling promotes myeloid cell infiltration in glioblastoma
Obacz, Joanna, Archambeau, Jérôme, Lafont, Elodie, Nivet, Manon, Martin, Sophie, Aubry, Marc, Voutetakis, Konstantinos, Pineau, Raphael, Boniface, Rachel, Sicari, Daria, Pelizzari-Raymundo, Diana, Ghukasyan, Gevorg, McGrath, Eoghan, Vlachavas, Efstathios-Iason, Le Gallo, Matthieu, Le Reste, Pierre Jean, Barroso, Kim, Fainsod-Levi, Tanya, Obiedat, Akram, Granot, Zvi, Tirosh, Boaz, Samal, Juhi, Pandit, Abhay, Négroni, Luc, Soriano, Nicolas, Monnier, Annabelle, Mosser, Jean, Chatziioannou, Aristotelis, Quillien, Véronique, Chevet, Eric, Avril, Tony
Published in Neuro-oncology (Charlottesville, Va.) (03.05.2024)
Published in Neuro-oncology (Charlottesville, Va.) (03.05.2024)
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Journal Article
CD112R에 대한 항체 및 이의 용도
LENAC ROVIS TIHANA, TSUKERMAN PINCHAS, MANDELBOIM OFER, OBIEDAT AKRAM, JONJIC STIPAN, KUCAN BRLIC PAOLA, CINAMON GUY, ATIEH ANAS
Year of Publication 22.11.2023
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Year of Publication 22.11.2023
Patent
Abstract 6657: Phase I trial of first-in-class anti-PVR mAb NTX1088: Restoration of DNAM1 expression as MOA for enhanced antitumor immunity
Atieh, Anas, Obiedat, Akram, Vitenshtein, Alon, Cinamon, Guy, Paz, Keren, lenac, Tihana, Kucan, Paola, Mazor, Marija, Mandelboim, Ofer, Jonji, Stipan, Tsukerman, Pini
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 5534: NTX-1088, a first-in-class anti-PVR mAb mediates DNAM1-dependent antitumor immunity
Obiedat, Akram, Atieh, Anas, Cinamon, Guy, Paz, Keren, Brilc, Paola Kucan, Hirsl, Lea, Roviš, Tihana Lenac, Mandelboim, Ofer, Jonjic, Stipan, Tsukerman, Pini
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
HUMANIZED ANTIBODIES AGAINST NECTIN-4 AND DRUG CONJUGATES THEREOF
VITENSHTEIN, Alon, CINAMON, Guy, TSUKERMAN, Pinchas, ATIEH, Anas, OBIEDAT, Akram
Year of Publication 28.03.2024
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Year of Publication 28.03.2024
Patent
DRUG CONJUGATES OF HUMANIZED ANTI PVR ANTIBODIES
VITENSHTEIN, Alon, CINAMON, Guy, TSUKERMAN, Pinchas, ATIEH, Anas, OBIEDAT, Akram
Year of Publication 07.03.2024
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Year of Publication 07.03.2024
Patent
ANTIBODIES AGAINST CD112R AND USES THEREOF
JONJIC, Stipan, LENAC ROVIŠ, Tihana, MANDELBOIM, Ofer, CINAMON, Guy, KUCAN BRLIC, Paola, TSUKERMAN, Pinchas, ATIEH, Anas, OBIEDAT, Akram
Year of Publication 15.08.2024
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Year of Publication 15.08.2024
Patent
ANTIBODIES AGAINST CD112R AND USES THEREOF
JONJIĆ, Stipan, LENAC ROVIŠ, Tihana, MANDELBOIM, Ofer, CINAMON, Guy, KUČAN BRLIĆ, Paola, TSUKERMAN, Pinchas, ATIEH, Anas, OBIEDAT, Akram
Year of Publication 11.01.2024
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Year of Publication 11.01.2024
Patent
ANTIBODIES AGAINST CD112R AND USES THEREOF
MANDELBOIM, Ofer, CINAMON, Guy, LENAC ROVIS, Tihana, KUCAN BRLIC, Paola, TSUKERMAN, Pinchas, JONJI, Stipan, ATIEH, Anas, OBIEDAT, Akram
Year of Publication 20.12.2023
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Year of Publication 20.12.2023
Patent
ANTIBODIES AGAINST CD112R AND USES THEREOF
JONJIĆ, Stipan, LENAC ROVIŠ, Tihana, MANDELBOIM, Ofer, CINAMON, Guy, KUČAN BRLIĆ, Paola, TSUKERMAN, Pinchas, ATIEH, Anas, OBIEDAT, Akram
Year of Publication 21.09.2023
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Year of Publication 21.09.2023
Patent