A perfused human blood-brain barrier on-a-chip for high-throughput assessment of barrier function and antibody transport
Wevers, Nienke R, Kasi, Dhanesh G, Gray, Taylor, Wilschut, Karlijn J, Smith, Benjamin, van Vught, Remko, Shimizu, Fumitaka, Sano, Yasuteru, Kanda, Takashi, Marsh, Graham, Trietsch, Sebastiaan J, Vulto, Paul, Lanz, Henriëtte L, Obermeier, Birgit
Published in Fluids and barriers of the CNS (31.08.2018)
Published in Fluids and barriers of the CNS (31.08.2018)
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Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins
Brändle, Simone M., Obermeier, Birgit, Senel, Makbule, Bruder, Jessica, Mentele, Reinhard, Khademi, Mohsen, Olsson, Tomas, Tumani, Hayrettin, Kristoferitsch, Wolfgang, Lottspeich, Friedrich, Wekerle, Hartmut, Hohlfeld, Reinhard, Dornmair, Klaus
Published in Proceedings of the National Academy of Sciences - PNAS (12.07.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (12.07.2016)
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Journal Article
Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis
Wekerle, Hartmut, Mentele, Reinhard, Kellermann, Josef, Malotka, Joachim, Obermeier, Birgit, Lottspeich, Friedrich, Dornmair, Klaus, Kümpfel, Tania, Hohlfeld, Reinhard
Published in Nature medicine (01.06.2008)
Published in Nature medicine (01.06.2008)
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Journal Article
Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging
Salman, Mootaz M, Marsh, Graham, Kusters, Ilja, Delincé, Matthieu, Di Caprio, Giuseppe, Upadhyayula, Srigokul, de Nola, Giovanni, Hunt, Ronan, Ohashi, Kazuka G, Gray, Taylor, Shimizu, Fumitaka, Sano, Yasuteru, Kanda, Takashi, Obermeier, Birgit, Kirchhausen, Tom
Published in Frontiers in bioengineering and biotechnology (28.09.2020)
Published in Frontiers in bioengineering and biotechnology (28.09.2020)
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Journal Article
Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?
Spampinato, Simona F, Obermeier, Birgit, Cotleur, Anne, Love, Anna, Takeshita, Yukio, Sano, Yasuteru, Kanda, Takashi, Ransohoff, Richard M
Published in PloS one (21.07.2015)
Published in PloS one (21.07.2015)
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Journal Article
Effects of neuromyelitis optica–IgG at the blood–brain barrier in vitro
Takeshita, Yukio, Obermeier, Birgit, Cotleur, Anne C, Spampinato, Simona F, Shimizu, Fumitaka, Yamamoto, Erin, Sano, Yasuteru, Kryzer, Thomas J, Lennon, Vanda A, Kanda, Takashi, Ransohoff, Richard M
Published in Neurology : neuroimmunology & neuroinflammation (01.01.2017)
Published in Neurology : neuroimmunology & neuroinflammation (01.01.2017)
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Journal Article
The blood–brain barrier
Obermeier, Birgit, Verma, Ajay, Ransohoff, Richard M.
Published in Handbook of Clinical Neurology (2016)
Published in Handbook of Clinical Neurology (2016)
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Book Chapter
Journal Article
Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica
Shimizu, Fumitaka, Schaller, Kristin L, Owens, Gregory P, Cotleur, Anne C, Kellner, Debra, Takeshita, Yukio, Obermeier, Birgit, Kryzer, Thomas J, Sano, Yasuteru, Kanda, Takashi, Lennon, Vanda A, Ransohoff, Richard M, Bennett, Jeffrey L
Published in Science translational medicine (05.07.2017)
Published in Science translational medicine (05.07.2017)
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Journal Article
Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammation
BELTRAN, Eduardo, OBERMEIER, Birgit, HOHLFELD, Reinhard, CASANOVA, Bonaventura, DORNMAIR, Klaus, MOSER, Markus, CORET, Francisco, SIMO-CASTELLO, María, BOSCA, Isabel, PEREZ-MIRALLES, Francisco, VILLAR, Luisa M, SENEL, Makbule, TUMANI, Hayrettin
Published in Brain (London, England : 1878) (01.10.2014)
Published in Brain (London, England : 1878) (01.10.2014)
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Journal Article
Target Specificity of an Autoreactive Pathogenic Human γδ-T Cell Receptor in Myositis
Bruder, Jessica, Siewert, Katherina, Obermeier, Birgit, Malotka, Joachim, Scheinert, Peter, Kellermann, Josef, Ueda, Takuya, Hohlfeld, Reinhard, Dornmair, Klaus
Published in The Journal of biological chemistry (15.06.2012)
Published in The Journal of biological chemistry (15.06.2012)
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Journal Article
Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin
Obermeier, Birgit, Lovato, Laura, Mentele, Reinhard, Brück, Wolfgang, Forne, Ignasi, Imhof, Axel, Lottspeich, Friedrich, Turk, Katherine W, Willis, Simon N, Wekerle, Hartmut, Hohlfeld, Reinhard, Hafler, David A, O'Connor, Kevin C, Dornmair, Klaus
Published in Journal of neuroimmunology (01.04.2011)
Published in Journal of neuroimmunology (01.04.2011)
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Journal Article
Novel insights into cell-cell interactions at the blood-brain barrier revealed by a fully-human flow-based in vitro model
Obermeier, Birgit, Benson, Bryan L, Lu, Haiyan, Kidd, Grahame, Spampinato, Simona, Takeshita, Yukio, Sano, Yasuteru, Kanda, Takashi, Ransohoff, Richard M
Published in Journal of neuroimmunology (01.01.2014)
Published in Journal of neuroimmunology (01.01.2014)
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Journal Article
Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?: e0133392
Spampinato, Simona F, Obermeier, Birgit, Cotleur, Anne, Love, Anna, Takeshita, Yukio, Sano, Yasuteru, Kanda, Takashi, Ransohoff, Richard M
Published in PloS one (01.07.2015)
Published in PloS one (01.07.2015)
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Journal Article
Deletion of a Stay-Green Gene Associates with Adaptive Selection in Brassica napus
Qian, Lunwen, Voss-Fels, Kai, Cui, Yixin, Jan, Habib U., Samans, Birgit, Obermeier, Christian, Qian, Wei, Snowdon, Rod J.
Published in Molecular plant (05.12.2016)
Published in Molecular plant (05.12.2016)
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Journal Article
An in-vitro BBB-on-a-chip open model of human blood-brain barrier enabling advanced optical imaging
Salman, Mootaz, Marsh, Graham, Kusters, Ilja, Delince, Matthieu, Giuseppe Di Caprio, Upadhyayula, Srigokul, De Nola, Giovanni, Hunt, Ronan, Ohashi, Kazuka G, Shimizu, Fumitaka, Sano, Yasuteru, Kanda, Takashi, Obermeier, Birgit, Kirchhausen, Tom
Published in bioRxiv (01.07.2020)
Published in bioRxiv (01.07.2020)
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