Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s
Oba, Takaaki, Long, Mark D, Keler, Tibor, Marsh, Henry C, Minderman, Hans, Abrams, Scott I, Liu, Song, Ito, Fumito
Published in Nature communications (27.10.2020)
Published in Nature communications (27.10.2020)
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T-cell CX3CR1 expression as a dynamic blood-based biomarker of response to immune checkpoint inhibitors
Yamauchi, Takayoshi, Hoki, Toshifumi, Oba, Takaaki, Jain, Vaibhav, Chen, Hongbin, Attwood, Kristopher, Battaglia, Sebastiano, George, Saby, Chatta, Gurkamal, Puzanov, Igor, Morrison, Carl, Odunsi, Kunle, Segal, Brahm H, Dy, Grace K, Ernstoff, Marc S, Ito, Fumito
Published in Nature communications (03.03.2021)
Published in Nature communications (03.03.2021)
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Local, multimodal intralesional therapy renders distant brain metastases susceptible to PD-L1 blockade in a preclinical model of triple-negative breast cancer
Yokoi, Toshihiro, Oba, Takaaki, Kajihara, Ryutaro, Abrams, Scott I, Ito, Fumito
Published in Scientific reports (09.11.2021)
Published in Scientific reports (09.11.2021)
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The mechanisms involved in the resistance of estrogen receptor-positive breast cancer cells to palbociclib are multiple and change over time
Ono, Mayu, Oba, Takaaki, Shibata, Tomohiro, Ito, Ken-ichi
Published in Journal of cancer research and clinical oncology (01.11.2021)
Published in Journal of cancer research and clinical oncology (01.11.2021)
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HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells
Oba, Takaaki, Ono, Mayu, Matoba, Hisanori, Uehara, Takeshi, Hasegawa, Yoshie, Ito, Ken-ichi
Published in Breast cancer research and treatment (01.02.2021)
Published in Breast cancer research and treatment (01.02.2021)
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CD40 and CD80/86 signaling in cDC1s mediate effective neoantigen vaccination and generation of antigen-specific CX3CR1+ CD8+ T cells
Yamauchi, Takayoshi, Hoki, Toshifumi, Oba, Takaaki, Kajihara, Ryutaro, Attwood, Kristopher, Cao, Xuefang, Ito, Fumito
Published in Cancer Immunology, Immunotherapy (01.01.2022)
Published in Cancer Immunology, Immunotherapy (01.01.2022)
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Comparative efficacy and safety of tyrosine kinase inhibitors for thyroid cancer: a systematic review and meta-analysis
Oba, Takaaki, Chino, Tatsunori, Soma, Ai, Shimizu, Tadafumi, Ono, Mayu, Ito, Tokiko, Kanai, Toshiharu, Maeno, Kazuma, Ito, Ken-ichi
Published in ENDOCRINE JOURNAL (01.01.2020)
Published in ENDOCRINE JOURNAL (01.01.2020)
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Skeletal muscle loss during neoadjuvant chemotherapy predicts poor prognosis in patients with breast cancer
Amitani, Masatsugu, Oba, Takaaki, Kiyosawa, Nami, Morikawa, Hiroki, Chino, Tatsunori, Soma, Ai, Shimizu, Tadafumi, Ohno, Koichi, Ono, Mayu, Ito, Tokiko, Kanai, Toshiharu, Maeno, Kazuma, Ito, Ken-Ichi
Published in BMC cancer (26.03.2022)
Published in BMC cancer (26.03.2022)
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Prognostic significance of neutrophil-to-lymphocyte ratio for long-term outcomes in patients with poorly differentiated thyroid cancer
Oba, Takaaki, Maeno, Kazuma, Amitani, Masatsugu, Shimizu, Tadafumi, Ohno, Koichi, Ono, Mayu, Ito, Tokiko, Kanai, Toshiharu, Uehara, Takeshi, Ito, Ken-ichi
Published in Endocrine Journal (01.01.2021)
Published in Endocrine Journal (01.01.2021)
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Generation of cDC-like cells from human induced pluripotent stem cells via Notch signaling
Makino, Kenichi, Long, Mark D, Kajihara, Ryutaro, Matsueda, Satoko, Oba, Takaaki, Kanehira, Kazunori, Liu, Song, Ito, Fumito
Published in Journal for immunotherapy of cancer (01.01.2022)
Published in Journal for immunotherapy of cancer (01.01.2022)
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Multicenter retrospective study on the use of Curebest™ 95GC Breast for estrogen receptor-positive and node-negative early breast cancer
Tsukamoto, Fumine, Arihiro, Koji, Takahashi, Mina, Ito, Ken-ichi, Ohsumi, Shozo, Takashima, Seiki, Oba, Takaaki, Yoshida, Masayuki, Kishi, Kazuki, Yamagishi, Keisuke, Kinoshita, Takayuki
Published in BMC cancer (05.10.2021)
Published in BMC cancer (05.10.2021)
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Surgical resection of the primary tumor prevents an undesirable locoregional condition and improves the quality of life in patients with anaplastic thyroid cancer
Kanai, Toshiharu, Ito, Tokiko, Morikawa, Hiroki, Amitani, Masatsugu, Shimizu, Tadafumi, Ohno, Koichi, Ono, Mayu, Oba, Takaaki, Maeno, Kazuma, Ito, Ken-ichi
Published in Surgery today (Tokyo, Japan) (01.11.2022)
Published in Surgery today (Tokyo, Japan) (01.11.2022)
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In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models
Oba, Takaaki, Makino, Kenichi, Kajihara, Ryutaro, Yokoi, Toshihiro, Araki, Ryoko, Abe, Masumi, Minderman, Hans, Chang, Alfred E, Odunsi, Kunle, Ito, Fumito
Published in Journal for immunotherapy of cancer (01.05.2021)
Published in Journal for immunotherapy of cancer (01.05.2021)
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44 Corticosteroids decrease efficacy of immune checkpoint inhibitor therapy and correlate with compromised CD8+ T-cell differentiation in patients with non-small cell lung cancer
Polyakov, Lauren, Oba, Takaaki, Chen, Hongbin, Abdelfatah, Eihab, Sarkar, Joy, Attwood, Kristopher, Sharma, Rajeev, Segal, Brahm, Dy, Grace, Ito, Fumito
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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