Search Results - "OTTHEINZ KREBS" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial

Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial

by Geletneky, Karsten, Hajda, Jacek, Angelova, Assia L., Leuchs, Barbara, Capper, David, Bartsch, Andreas J., Neumann, Jan-Oliver, Schöning, Tilman, Hüsing, Johannes, Beelte, Birgit, Kiprianova, Irina, Roscher, Mandy, Bhat, Rauf, von Deimling, Andreas, Brück, Wolfgang, Just, Alexandra, Frehtman, Veronika, Löbhard, Stephanie, Terletskaia-Ladwig, Elena, Fry, Jeremy, Jochims, Karin, Daniel, Volker, Krebs, Ottheinz, Dahm, Michael, Huber, Bernard, Unterberg, Andreas, Rommelaere, Jean
Published in Molecular therapy (06.12.2017)

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Journal Article

Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

by Geletneky, Karsten, Huesing, Johannes, Rommelaere, Jean, Schlehofer, Joerg R, Leuchs, Barbara, Dahm, Michael, Krebs, Ottheinz, von Knebel Doeberitz, Magnus, Huber, Bernard, Hajda, Jacek
Published in BMC cancer (21.03.2012)

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A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol

A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol

by Hajda, Jacek, Lehmann, Monika, Krebs, Ottheinz, Kieser, Meinhard, Geletneky, Karsten, Jäger, Dirk, Dahm, Michael, Huber, Bernard, Schöning, Tilman, Sedlaczek, Oliver, Stenzinger, Albrecht, Halama, Niels, Daniel, Volker, Leuchs, Barbara, Angelova, Assia, Rommelaere, Jean, Engeland, Christine E, Springfeld, Christoph, Ungerechts, Guy
Published in BMC cancer (29.08.2017)

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Journal Article

Developmental regulation of hyaluronan-binding protein (RHAMM/IHABP) expression in early bovine embryos

Developmental regulation of hyaluronan-binding protein (RHAMM/IHABP) expression in early bovine embryos

by Stojkovic, M, Krebs, O, Kolle, S, Prelle, K, Assmann, V, Zakhartchenko, V, Sinowatz, F, Wolf, E
Published in Biology of reproduction (2003)

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Journal Article

Stability and safety key factors of the oncolytic protoparvovirus H-1 from manufacturing to human application

Stability and safety key factors of the oncolytic protoparvovirus H-1 from manufacturing to human application

by Frehtman, Veronika, Wohlfarth, Daniel, Müller, Marcus, Krebs, Ottheinz, Leuchs, Barbara
Published in Applied microbiology and biotechnology (01.08.2023)

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Journal Article

Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud

Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud

by Krebs, Ottheinz, Schreiner, Claire M, Scott, Jr, William J, Bell, Sheila M, Robbins, David J, Goetz, John A, Alt, Heidi, Hawes, Norm, Wolf, Eckhard, Favor, Jack
Published in Development (Cambridge) (01.12.2003)

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Phase 2 Trial of Oncolytic H-1 Parvovirus Therapy Shows Safety and Signs of Immune System Activation in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Phase 2 Trial of Oncolytic H-1 Parvovirus Therapy Shows Safety and Signs of Immune System Activation in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

by Hajda, Jacek, Leuchs, Barbara, Angelova, Assia L, Frehtman, Veronika, Rommelaere, Jean, Mertens, Mieke, Pilz, Maximilian, Kieser, Meinhard, Krebs, Ottheinz, Dahm, Michael, Huber, Bernard, Engeland, Christine E, Mavratzas, Athanasios, Hohmann, Nicolas, Schreiber, Jutta, Jäger, Dirk, Halama, Niels, Sedlaczek, Oliver, Gaida, Matthias M, Daniel, Volker, Springfeld, Christoph, Ungerechts, Guy
Published in Clinical cancer research (15.10.2021)

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First combined intravenous and intracerebral application of an oncolytic virus, parvovirus h-1, in a phase I/IIa clinical trial in patients with recurrent glioblastoma multiforme (ParvOryx01)

First combined intravenous and intracerebral application of an oncolytic virus, parvovirus h-1, in a phase I/IIa clinical trial in patients with recurrent glioblastoma multiforme (ParvOryx01)

by Geletneky, Karsten, Huesing, Johannes, Dahm, Michael, Krebs, Ottheinz, Huber, Bernard, Capper, David, Rommelaere, Jean, Hajda, Jacek, Unterberg, Andreas
Published in Journal of clinical oncology (20.05.2014)

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Journal Article

Bioavailability, Biodistribution, and CNS Toxicity of Clinical-Grade Parvovirus H1 after Intravenous and Intracerebral Injection in Rats

Bioavailability, Biodistribution, and CNS Toxicity of Clinical-Grade Parvovirus H1 after Intravenous and Intracerebral Injection in Rats

by Geletneky, Karsten, Leoni, Anne-Laure, Pohlmeyer-Esch, Gabriele, Loebhard, Stephanie, Leuchs, Barbara, Hoefer, Constance, Jochims, Karin, Dahm, Michael, Huber, Bernard, Rommelaere, Jean, Krebs, Ottheinz, Hajda, Jacek
Published in Comparative medicine (01.02.2015)

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Journal Article

ET-21COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER

ET-21COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER

by Geletneky, Karsten, Angelova, Assia, Leuchs, Barbara, Bhat, Rauf, Just, Alexandra, Capper, David, Krebs, Ottheinz, Dahm, Michael, Huber, Bernard, Unterberg, Andreas, Hajda, Jacek, Rommelaere, Jean
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)

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Journal Article

Pathology, Organ Distribution, and Immune Response after Single and Repeated Intravenous Injection of Rats with Clinical-Grade Parvovirus H1

Pathology, Organ Distribution, and Immune Response after Single and Repeated Intravenous Injection of Rats with Clinical-Grade Parvovirus H1

by Geletneky, Karsten, Leoni, Anne-Laure, Pohlmeyer-Esch, Gabriele, Loebhard, Stephanie, Baetz, Andrea, Leuchs, Barbara, Roscher, Mandy, Hoefer, Constance, Jochims, Karin, Dahm, Michael, Huber, Bernard, Rommelaere, Jean, Krebs, Ottheinz, Hajda, Jacek
Published in Comparative medicine (01.02.2015)

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Journal Article

ET-21 COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER

ET-21 COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER

by Geletneky, K., Angelova, A., Leuchs, B., Bhat, R., Just, A., Capper, D., Krebs, O., Dahm, M., Huber, B., Unterberg, A., Hajda, J., Rommelaere, J.
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)

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Insulin-like Growth Factor-Binding Protein-5 Inhibits Growth and Induces Differentiation of Mouse Osteosarcoma Cells

Insulin-like Growth Factor-Binding Protein-5 Inhibits Growth and Induces Differentiation of Mouse Osteosarcoma Cells

by Schneider, Marlon R., Zhou, Rui, Hoeflich, Andreas, Krebs, Ottheinz, Schmidt, Jörg, Mohan, Subburaman, Wolf, Eckhard, Lahm, Harald
Published in Biochemical and biophysical research communications (26.10.2001)

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Overexpression of Insulin-like Growth Factor-II in Mouse Embryonic Stem Cells Promotes Myogenic Differentiation

Overexpression of Insulin-like Growth Factor-II in Mouse Embryonic Stem Cells Promotes Myogenic Differentiation

by Prelle, Katja, Wobus, Anna M., Krebs, Ottheinz, Blum, Werner F., Wolf, Eckhard
Published in Biochemical and biophysical research communications (02.11.2000)

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Journal Article

OPTIMIZED PARVOVIRUS H-1 PRODUCTION

OPTIMIZED PARVOVIRUS H-1 PRODUCTION

by LEUCHS, Barbara, KREBS, Ottheinz, ROMMELAERE, Jean, FREHTMAN, Veronika, MÜLLER, Marcus, DAHM, Michael
Year of Publication 02.06.2022

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Patent

Parvovirus formulation for treating tumors

Parvovirus formulation for treating tumors

by Leuchs, Barbara, Dahm, Michael, Geletneky, Karsten, Dinsart, Christiane, Krebs, Ottheinz, Rommelaere, Jean
Year of Publication 10.05.2022

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Patent

OPTIMIZED PARVOVIRUS H-1 PRODUCTION

OPTIMIZED PARVOVIRUS H-1 PRODUCTION

by LEUCHS, Barbara, KREBS, Ottheinz, ROMMELAERE, Jean, FREHTMAN, Veronika, MÜLLER, Marcus, DAHM, Michael
Year of Publication 20.04.2022

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Patent

Developmental Regulation of Hyaluronan-Binding Protein (RHAMM/IHABP) Expression in Early Bovine Embryos1

Developmental Regulation of Hyaluronan-Binding Protein (RHAMM/IHABP) Expression in Early Bovine Embryos1

by Stojkovic, Miodrag, Krebs, Ottheinz, Kölle, Sabine, Prelle, Katja, Assmann, Volker, Zakhartchenko, Valeri, Sinowatz, Fred, Wolf, Eckhard
Published in Biology of reproduction (01.01.2003)

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Journal Article

Optimized parvovirus H-1 production

Optimized parvovirus H-1 production

by LEUCHS, Barbara, KREBS, Ottheinz, ROMMELAERE, Jean, FREHTMAN, Veronika, MÜLLER, Marcus, DAHM, Michael
Year of Publication 02.12.2021

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Patent

PARVOVIRUS FORMULATION FOR TREATING TUMORS

PARVOVIRUS FORMULATION FOR TREATING TUMORS

by GELETNEKY, KARSTEN, DAHM, MICHAEL, LEUCHS, BARBARA, KREBS, OTTHEINZ, ROMMELAERE, JEAN, DINSART, CHRISTIANE
Year of Publication 09.02.2021

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Patent