MiR-744-5p inducing cell death by directly targeting HNRNPC and NFIX in ovarian cancer cells
Kleemann, Michael, Schneider, Helga, Unger, Kristian, Sander, Philip, Schneider, E. Marion, Fischer-Posovszky, Pamela, Handrick, René, Otte, Kerstin
Published in Scientific reports (13.06.2018)
Published in Scientific reports (13.06.2018)
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Journal Article
Exploring synthetic biology for the development of a sensor cell line for automated bioprocess control
Zeh, Nikolas, Bräuer, Melina, Raab, Nadja, Handrick, René, Otte, Kerstin
Published in Scientific reports (10.02.2022)
Published in Scientific reports (10.02.2022)
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Journal Article
Exploring the molecular content of CHO exosomes during bioprocessing
Keysberg, Christoph, Hertel, Oliver, Schelletter, Louise, Busche, Tobias, Sochart, Chiara, Kalinowski, Jörn, Hoffrogge, Raimund, Otte, Kerstin, Noll, Thomas
Published in Applied microbiology and biotechnology (01.05.2021)
Published in Applied microbiology and biotechnology (01.05.2021)
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Journal Article
Unraveling what makes a monoclonal antibody difficult‐to‐express: From intracellular accumulation to incomplete folding and degradation via ERAD
Mathias, Sven, Wippermann, Anna, Raab, Nadja, Zeh, Nikolas, Handrick, René, Gorr, Ingo, Schulz, Patrick, Fischer, Simon, Gamer, Martin, Otte, Kerstin
Published in Biotechnology and bioengineering (01.01.2020)
Published in Biotechnology and bioengineering (01.01.2020)
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Journal Article
Human CAP cells represent a novel source for functional, miRNA-loaded exosome production
Zeh, Nikolas, Schneider, Helga, Mathias, Sven, Raab, Nadja, Kleemann, Michael, Schmidt-Hertel, Sabine, Weis, Benjamin, Wissing, Silke, Strempel, Nikola, Handrick, René, Otte, Kerstin
Published in PloS one (28.08.2019)
Published in PloS one (28.08.2019)
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Journal Article
GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells
Schrade, Anja, Kyrönlahti, Antti, Akinrinade, Oyediran, Pihlajoki, Marjut, Fischer, Simon, Rodriguez, Verena Martinez, Otte, Kerstin, Velagapudi, Vidya, Toppari, Jorma, Wilson, David B, Heikinheimo, Markku
Published in Endocrinology (Philadelphia) (01.06.2016)
Published in Endocrinology (Philadelphia) (01.06.2016)
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Stable overexpression of native and artificial miRNAs for the production of differentially fucosylated antibodies in CHO cells
Schlossbauer, Patrick, Naumann, Lukas, Klingler, Florian, Burkhart, Madina, Handrick, René, Korff, Kathrin, Neusüß, Christian, Otte, Kerstin, Hesse, Friedemann
Published in Engineering in life sciences (01.06.2024)
Published in Engineering in life sciences (01.06.2024)
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Illuminating a biologics development challenge: systematic characterization of CHO cell-derived hydrolases identified in monoclonal antibody formulations
Maier, Melanie, Weiß, Linus, Zeh, Nikolas, Schmieder-Todtenhaupt, Valerie, Dehghani, Alireza, Felix, Marius Nicolaus, Heinzelmann, Daniel, Lindner, Benjamin, Schmidt, Moritz, Studts, Joey, Schulz, Patrick, Reisinger, Bernd, Otte, Kerstin, Franzreb, Matthias, Lakatos, Daniel, Fischer, Simon
Published in mAbs (31.12.2024)
Published in mAbs (31.12.2024)
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Journal Article
Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain
Bauer, Joschka, Mathias, Sven, Kube, Sebastian, Otte, Kerstin, Garidel, Patrick, Gamer, Martin, Blech, Michaela, Fischer, Simon, Karow-Zwick, Anne R
Published in mAbs (01.01.2020)
Published in mAbs (01.01.2020)
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Journal Article
Cell line development for continuous high cell density biomanufacturing: Exploiting hypoxia for improved productivity
Zeh, Nikolas, Schlossbauer, Patrick, Raab, Nadja, Klingler, Florian, Handrick, René, Otte, Kerstin
Published in Metabolic engineering communications (01.12.2021)
Published in Metabolic engineering communications (01.12.2021)
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Journal Article
mir-124-5p Regulates Phagocytosis of Human Macrophages by Targeting the Actin Cytoskeleton via the ARP2/3 Complex
Herdoiza Padilla, Estefania, Crauwels, Peter, Bergner, Tim, Wiederspohn, Nicole, Förstner, Sabrina, Rinas, Rebecca, Ruf, Anna, Kleemann, Michael, Handrick, René, Tuckermann, Jan, Otte, Kerstin, Walther, Paul, Riedel, Christian U
Published in Frontiers in immunology (04.10.2019)
Published in Frontiers in immunology (04.10.2019)
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Journal Article
Establishment of lipofection for studying miRNA function in human adipocytes
Enlund, Eveliina, Fischer, Simon, Handrick, René, Otte, Kerstin, Debatin, Klaus-Michael, Wabitsch, Martin, Fischer-Posovszky, Pamela
Published in PloS one (21.05.2014)
Published in PloS one (21.05.2014)
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Identification of Farnesoid X Receptor β as a Novel Mammalian Nuclear Receptor Sensing Lanosterol
Otte, Kerstin, Kranz, Harald, Kober, Ingo, Thompson, Paul, Hoefer, Michael, Haubold, Bernhard, Remmel, Bettina, Voss, Hartmut, Kaiser, Carmen, Albers, Michael, Cheruvallath, Zaccharias, Jackson, David, Casari, Georg, Koegl, Manfred, Pääbo, Svante, Mous, Jan, Kremoser, Claus, Deuschle, Ulrich
Published in Molecular and Cellular Biology (01.02.2003)
Published in Molecular and Cellular Biology (01.02.2003)
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Journal Article
The potential of emerging sub-omics technologies for CHO cell engineering
Jerabek, Tobias, Keysberg, Christoph, Otte, Kerstin
Published in Biotechnology advances (01.10.2022)
Published in Biotechnology advances (01.10.2022)
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Journal Article
Hyperthermic shift and cell engineering increase small extracellular vesicle production in HEK293F cells
Keysberg, Christoph, Hertel, Oliver, Hoffrogge, Raimund, Reich, Sibylle, Hornung, Nadine, Holzmann, Karlheinz, Otte, Kerstin
Published in Biotechnology and bioengineering (01.03.2024)
Published in Biotechnology and bioengineering (01.03.2024)
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Journal Article
Life at the periphery: what makes CHO cells survival talents
Jerabek, Tobias, Klingler, Florian, Raab, Nadja, Zeh, Nikolas, Pfannstiel, Jens, Otte, Kerstin
Published in Applied microbiology and biotechnology (01.09.2022)
Published in Applied microbiology and biotechnology (01.09.2022)
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Journal Article
Spatial Proteomics Reveals Differences in the Cellular Architecture of Antibody-Producing CHO and Plasma Cell–Derived Cells
Kretz, Robin, Walter, Larissa, Raab, Nadja, Zeh, Nikolas, Gauges, Ralph, Otte, Kerstin, Fischer, Simon, Stoll, Dieter
Published in Molecular & cellular proteomics (01.10.2022)
Published in Molecular & cellular proteomics (01.10.2022)
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