Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, two-stage, multi-arm, phase 1/2 trial
Sharma, Padmanee, Prof, Callahan, Margaret K, MD, Bono, Petri, MD, Kim, Joseph, MD, Spiliopoulou, Pavlina, MD, Calvo, Emiliano, MD, Pillai, Rathi N, MD, Ott, Patrick A, MD, de Braud, Filippo, Prof, Morse, Michael, Prof, Le, Dung T, MD, Jaeger, Dirk, MD, Chan, Emily, MD, Harbison, Chris, PhD, Lin, Chen-Sheng, PhD, Tschaika, Marina, MD, Azrilevich, Alex, PharmD, Rosenberg, Jonathan E, MD
Published in The lancet oncology (01.11.2016)
Published in The lancet oncology (01.11.2016)
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Pan-tumor genomic biomarkers for PD-1 checkpoint blockade-based immunotherapy
Cristescu, Razvan, Mogg, Robin, Ayers, Mark, Albright, Andrew, Murphy, Erin, Yearley, Jennifer, Sher, Xinwei, Liu, Xiao Qiao, Lu, Hongchao, Nebozhyn, Michael, Zhang, Chunsheng, Lunceford, Jared K, Joe, Andrew, Cheng, Jonathan, Webber, Andrea L, Ibrahim, Nageatte, Plimack, Elizabeth R, Ott, Patrick A, Seiwert, Tanguy Y, Ribas, Antoni, McClanahan, Terrill K, Tomassini, Joanne E, Loboda, Andrey, Kaufman, David
Published in Science (American Association for the Advancement of Science) (12.10.2018)
Published in Science (American Association for the Advancement of Science) (12.10.2018)
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PD-1 Inhibitor-Related Pneumonitis in Advanced Cancer Patients: Radiographic Patterns and Clinical Course
Nishino, Mizuki, Ramaiya, Nikhil H, Awad, Mark M, Sholl, Lynette M, Maattala, Jennifer A, Taibi, Myriam, Hatabu, Hiroto, Ott, Patrick A, Armand, Philippe F, Hodi, F Stephen
Published in Clinical cancer research (15.12.2016)
Published in Clinical cancer research (15.12.2016)
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Journal Article
Safety and Efficacy of Pembrolizumab in Advanced, Programmed Death Ligand 1-Positive Cervical Cancer: Results From the Phase Ib KEYNOTE-028 Trial
Frenel, Jean-Sebastien, Le Tourneau, Christophe, O'Neil, Bert, Ott, Patrick A, Piha-Paul, Sarina A, Gomez-Roca, Carlos, van Brummelen, Emilie M J, Rugo, Hope S, Thomas, Shari, Saraf, Sanatan, Rangwala, Reshma, Varga, Andrea
Published in Journal of clinical oncology (20.12.2017)
Published in Journal of clinical oncology (20.12.2017)
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Journal Article
Safety and Antitumor Activity of Pembrolizumab in Advanced Programmed Death Ligand 1-Positive Endometrial Cancer: Results From the KEYNOTE-028 Study
Ott, Patrick A, Bang, Yung-Jue, Berton-Rigaud, Dominique, Elez, Elena, Pishvaian, Michael J, Rugo, Hope S, Puzanov, Igor, Mehnert, Janice M, Aung, Kyaw L, Lopez, Juanita, Carrigan, Marion, Saraf, Sanatan, Chen, Mei, Soria, Jean-Charles
Published in Journal of clinical oncology (01.08.2017)
Published in Journal of clinical oncology (01.08.2017)
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Journal Article
Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial
Hodi, F Stephen, Dr, Chesney, Jason, Prof, Pavlick, Anna C, MD, Robert, Caroline, Prof, Grossmann, Kenneth F, MD, McDermott, David F, MD, Linette, Gerald P, MD, Meyer, Nicolas, Prof, Giguere, Jeffrey K, MD, Agarwala, Sanjiv S, Prof, Shaheen, Montaser, MD, Ernstoff, Marc S, Prof, Minor, David R, MD, Salama, April K, MD, Taylor, Matthew H, MD, Ott, Patrick A, MD, Horak, Christine, PhD, Gagnier, Paul, MD, Jiang, Joel, PhD, Wolchok, Jedd D, Prof, Postow, Michael A, MD
Published in The lancet oncology (01.11.2016)
Published in The lancet oncology (01.11.2016)
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Journal Article
Nivolumab Monotherapy and Nivolumab Plus Ipilimumab in Recurrent Small Cell Lung Cancer: Results From the CheckMate 032 Randomized Cohort
Ready, Neal E., Ott, Patrick A., Hellmann, Matthew D., Zugazagoitia, Jon, Hann, Christine L., de Braud, Filippo, Antonia, Scott J., Ascierto, Paolo A., Moreno, Victor, Atmaca, Akin, Salvagni, Stefania, Taylor, Matthew, Amin, Asim, Camidge, D. Ross, Horn, Leora, Calvo, Emiliano, Li, Ang, Lin, Wen Hong, Callahan, Margaret K., Spigel, David R.
Published in Journal of thoracic oncology (01.03.2020)
Published in Journal of thoracic oncology (01.03.2020)
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Journal Article
Comprehensive Meta-analysis of Key Immune-Related Adverse Events from CTLA-4 and PD-1/PD-L1 Inhibitors in Cancer Patients
De Velasco, Guillermo, Je, Youjin, Bossé, Dominick, Awad, Mark M, Ott, Patrick A, Moreira, Raphael B, Schutz, Fabio, Bellmunt, Joaquim, Sonpavde, Guru P, Hodi, F Stephen, Choueiri, Toni K
Published in Cancer immunology research (01.04.2017)
Published in Cancer immunology research (01.04.2017)
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Journal Article
Inhibition of Immune Checkpoints and Vascular Endothelial Growth Factor as Combination Therapy for Metastatic Melanoma: An Overview of Rationale, Preclinical Evidence, and Initial Clinical Data
Ott, Patrick A, Hodi, F Stephen, Buchbinder, Elizabeth I
Published in Frontiers in oncology (22.09.2015)
Published in Frontiers in oncology (22.09.2015)
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Journal Article
The efficacy of anti‐PD‐1 agents in acral and mucosal melanoma
Shoushtari, Alexander N., Munhoz, Rodrigo R., Kuk, Deborah, Ott, Patrick A., Johnson, Douglas B., Tsai, Katy K., Rapisuwon, Suthee, Eroglu, Zeynep, Sullivan, Ryan J., Luke, Jason J., Gangadhar, Tara C., Salama, April K. S., Clark, Varina, Burias, Clare, Puzanov, Igor, Atkins, Michael B., Algazi, Alain P., Ribas, Antoni, Wolchok, Jedd D., Postow, Michael A.
Published in Cancer (01.11.2016)
Published in Cancer (01.11.2016)
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Journal Article
The Impact of Radiation Therapy on Lymphocyte Count and Survival in Metastatic Cancer Patients Receiving PD-1 Immune Checkpoint Inhibitors
Pike, Luke R.G., Bang, Andrew, Mahal, Brandon A., Taylor, Allison, Krishnan, Monica, Spektor, Alexander, Cagney, Daniel N., Aizer, Ayal A., Alexander, Brian M., Rahma, Osama, Balboni, Tracy, Ott, Patrick A., Hodi, F. Stephen, Schoenfeld, Jonathan D.
Published in International journal of radiation oncology, biology, physics (01.01.2019)
Published in International journal of radiation oncology, biology, physics (01.01.2019)
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Journal Article
Cardiotoxicity associated with CTLA4 and PD1 blocking immunotherapy
Heinzerling, Lucie, Ott, Patrick A., Hodi, F. Stephen, Husain, Aliya N., Tajmir-Riahi, Azadeh, Tawbi, Hussein, Pauschinger, Matthias, Gajewski, Thomas F., Lipson, Evan J., Luke, Jason J.
Published in Journal for immunotherapy of cancer (16.08.2016)
Published in Journal for immunotherapy of cancer (16.08.2016)
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Journal Article
Pembrolizumab for the treatment of programmed death–ligand 1‒positive advanced carcinoid or pancreatic neuroendocrine tumors: Results from the KEYNOTE‐028 study
Mehnert, Janice M., Bergsland, Emily, O’Neil, Bert H., Santoro, Armando, Schellens, Jan H. M., Cohen, Roger B., Doi, Toshihiko, Ott, Patrick A., Pishvaian, Michael J., Puzanov, Igor, Aung, Kyaw L., Hsu, Chiun, Le Tourneau, Christophe, Hollebecque, Antoine, Élez, Elena, Tamura, Kenji, Gould, Marlena, Yang, Ping, Stein, Karen, Piha‐Paul, Sarina A.
Published in Cancer (01.07.2020)
Published in Cancer (01.07.2020)
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Journal Article
Phase II Study of the MEK1/MEK2 Inhibitor Trametinib in Patients With Metastatic BRAF-Mutant Cutaneous Melanoma Previously Treated With or Without a BRAF Inhibitor
KIM, Kevin B, KEFFORD, Richard, GONZALEZ, Rene, OTT, Patrick A, LONG, Georgina V, GARDNER, Olivia S, OUELLET, Daniele, YANMEI XU, DEMARINI, Douglas J, LE, Ngocdiep T, PATEL, Kiran, LEWIS, Karl D, PAVLICK, Anna C, INFANTE, Jeffrey R, RIBAS, Antoni, SOSMAN, Jeffrey A, FECHER, Leslie A, MILLWARD, Michael, MCARTHUR, GrantA, HWU, Patrick
Published in Journal of clinical oncology (01.02.2013)
Published in Journal of clinical oncology (01.02.2013)
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Journal Article
Clonal dynamics of alloreactive T cells in kidney allograft rejection after anti-PD-1 therapy
Dunlap, Garrett S, DiToro, Daniel, Henderson, Joel, Shah, Sujal I, Manos, Mike, Severgnini, Mariano, Weins, Astrid, Guleria, Indira, Ott, Patrick A, Murakami, Naoka, Rao, Deepak A
Published in Nature communications (21.03.2023)
Published in Nature communications (21.03.2023)
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