Liposome-based nanocapsules for the controlled release of dietary curcumin: PDDA and silica nanoparticle-coated DMPC liposomes enhance the fluorescence efficiency and anticancer activity of curcumin
Othman, Alaa K, El Kurdi, Riham, Badran, Adnan, Mesmar, Joelle, Baydoun, Elias, Patra, Digambara
Published in RSC advances (07.04.2022)
Published in RSC advances (07.04.2022)
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Journal Article
Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control
Mueller, Daniel M, Allenspach, Martina, Othman, Alaa, Saely, Christoph H, Muendlein, Axel, Vonbank, Alexander, Drexel, Heinz, von Eckardstein, Arnold
Published in Atherosclerosis (01.12.2015)
Published in Atherosclerosis (01.12.2015)
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Journal Article
Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration
Storti, Federica, Klee, Katrin, Todorova, Vyara, Steiner, Regula, Othman, Alaa, van der Velde-Visser, Saskia, Samardzija, Marijana, Meneau, Isabelle, Barben, Maya, Karademir, Duygu, Pauzuolyte, Valda, Boye, Sanford L, Blaser, Frank, Ullmer, Christoph, Dunaief, Joshua L, Hornemann, Thorsten, Rohrer, Lucia, den Hollander, Anneke, von Eckardstein, Arnold, Fingerle, Jürgen, Maugeais, Cyrille, Grimm, Christian
Published in eLife (13.03.2019)
Published in eLife (13.03.2019)
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Journal Article
Structure of the connexin-43 gap junction channel in a putative closed state
Qi, Chao, Acosta Gutierrez, Silvia, Lavriha, Pia, Othman, Alaa, Lopez-Pigozzi, Diego, Bayraktar, Erva, Schuster, Dina, Picotti, Paola, Zamboni, Nicola, Bortolozzi, Mario, Gervasio, Francesco Luigi, Korkhov, Volodymyr M
Published in eLife (03.08.2023)
Published in eLife (03.08.2023)
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Journal Article
NPC1 links cholesterol trafficking to microglial morphology via the gastrosome
Zareba, Joanna, Cattaneo, Elena F., Villani, Ambra, Othman, Alaa, Streb, Sebastian, Peri, Francesca
Published in Nature communications (05.10.2024)
Published in Nature communications (05.10.2024)
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Journal Article
Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction
Alecu, Irina, Tedeschi, Andrea, Behler, Natascha, Wunderling, Klaus, Lamberz, Christian, Lauterbach, MarioA.R., Gaebler, Anne, Ernst, Daniela, Van Veldhoven, Paul P., Al-Amoudi, Ashraf, Latz, Eicke, Othman, Alaa, Kuerschner, Lars, Hornemann, Thorsten, Bradke, Frank, Thiele, Christoph, Penno, Anke
Published in Journal of lipid research (01.01.2017)
Published in Journal of lipid research (01.01.2017)
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Journal Article
HSAN1 mutations in serine palmitoyltransferase reveal a close structure-function-phenotype relationship
Bode, Heiko, Bourquin, Florence, Suriyanarayanan, Saranya, Wei, Yu, Alecu, Irina, Othman, Alaa, Von Eckardstein, Arnold, Hornemann, Thorsten
Published in Human molecular genetics (01.03.2016)
Published in Human molecular genetics (01.03.2016)
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Journal Article
DEGS1-associated aberrant sphingolipid metabolism impairs nervous system function in humans
Karsai, Gergely, Kraft, Florian, Haag, Natja, Korenke, G Christoph, Hänisch, Benjamin, Othman, Alaa, Suriyanarayanan, Saranya, Steiner, Regula, Knopp, Cordula, Mull, Michael, Bergmann, Markus, Schröder, J Michael, Weis, Joachim, Elbracht, Miriam, Begemann, Matthias, Hornemann, Thorsten, Kurth, Ingo
Published in The Journal of clinical investigation (01.03.2019)
Published in The Journal of clinical investigation (01.03.2019)
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Journal Article
Viral serine palmitoyltransferase induces metabolic switch in sphingolipid biosynthesis and is required for infection of a marine alga
Ziv, Carmit, Malitsky, Sergey, Othman, Alaa, Ben-Dor, Shifra, Wei, Yu, Zheng, Shuning, Aharoni, Asaph, Hornemann, Thorsten, Vardi, Assaf
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2016)
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Journal Article
A functional analysis of 180 cancer cell lines reveals conserved intrinsic metabolic programs
Cherkaoui, Sarah, Durot, Stephan, Bradley, Jenna, Critchlow, Susan, Dubuis, Sebastien, Masiero, Mauro Miguel, Wegmann, Rebekka, Snijder, Berend, Othman, Alaa, Bendtsen, Claus, Zamboni, Nicola
Published in Molecular systems biology (01.11.2022)
Published in Molecular systems biology (01.11.2022)
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Journal Article
Neurotoxic 1-deoxysphingolipids and paclitaxel-induced peripheral neuropathy
Kramer, Rita, Bielawski, Jacek, Kistner-Griffin, Emily, Othman, Alaa, Alecu, Irina, Ernst, Daniela, Kornhauser, Drew, Hornemann, Thorsten, Spassieva, Stefka
Published in The FASEB journal (01.11.2015)
Published in The FASEB journal (01.11.2015)
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Journal Article
Explaining ionic liquid water solubility in terms of cation and anion hydrophobicity
Ranke, Johannes, Othman, Alaa, Fan, Ping, Müller, Anja
Published in International journal of molecular sciences (01.03.2009)
Published in International journal of molecular sciences (01.03.2009)
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Journal Article
Basal re-esterification finetunes mitochondrial fatty acid utilization
Sharma, Anand Kumar, Wang, Tongtong, Othman, Alaa, Khandelwal, Radhika, Balaz, Miroslav, Modica, Salvatore, Zamboni, Nicola, Wolfrum, Christian
Published in Molecular metabolism (Germany) (01.05.2023)
Published in Molecular metabolism (Germany) (01.05.2023)
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Journal Article
The reactive pyruvate metabolite dimethylglyoxal mediates neurological consequences of diabetes
Rhein, Sina, Costalunga, Riccardo, Inderhees, Julica, Gürtzgen, Tammo, Faupel, Teresa Christina, Shaheryar, Zaib, Arrulo Pereira, Adriana, Othman, Alaa, Begemann, Kimberly, Binder, Sonja, Stölting, Ines, Dorta, Valentina, Nawroth, Peter P., Fleming, Thomas, Oexle, Konrad, Prevot, Vincent, Nogueiras, Ruben, Meyhöfer, Svenja, Meyhöfer, Sebastian M., Schwaninger, Markus
Published in Nature communications (10.07.2024)
Published in Nature communications (10.07.2024)
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Journal Article
Hyperglycemia in Stroke Impairs Polarization of Monocytes/Macrophages to a Protective Noninflammatory Cell Type
Khan, Mahtab A, Schultz, Sina, Othman, Alaa, Fleming, Thomas, Lebrón-Galán, Rafael, Rades, Dirk, Clemente, Diego, Nawroth, Peter P, Schwaninger, Markus
Published in The Journal of neuroscience (07.09.2016)
Published in The Journal of neuroscience (07.09.2016)
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Journal Article
Hepatocyte ABCA1 deficiency is associated with reduced HDL sphingolipids
Othman, Alaa, Liu, Mingxia, Bode, Heiko, Boudyguina, Elena, von Eckardstein, Arnold, Parks, John S, Hornemann, Thorsten
Published in Frontiers in physiology (04.08.2023)
Published in Frontiers in physiology (04.08.2023)
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Journal Article
Astrocyte glutathione maintains endothelial barrier stability
Huang, Sheng-Fu, Othman, Alaa, Koshkin, Alexey, Fischer, Sabrina, Fischer, David, Zamboni, Nicola, Ono, Katsuhiko, Sawa, Tomohiro, Ogunshola, Omolara O.
Published in Redox biology (01.07.2020)
Published in Redox biology (01.07.2020)
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Journal Article
Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitus
Steiner, Carine, Othman, Alaa, Saely, Christoph H, Rein, Philipp, Drexel, Heinz, von Eckardstein, Arnold, Rentsch, Katharina M
Published in PloS one (14.11.2011)
Published in PloS one (14.11.2011)
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Journal Article
Glyoxal in hyperglycaemic ischemic stroke - a cohort study
Rhein, Sina, Inderhees, Julica, Herrmann, Oliver, Othman, Alaa, Begemann, Kimberly, Fleming, Thomas, Nawroth, Peter P, Klika, Karel D, Isa, Rakad, König, Inke R, Royl, Georg, Schwaninger, Markus
Published in Cardiovascular diabetology (12.07.2023)
Published in Cardiovascular diabetology (12.07.2023)
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Journal Article