An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells
Bowling, Sarah, Sritharan, Duluxan, Osorio, Fernando G., Nguyen, Maximilian, Cheung, Priscilla, Rodriguez-Fraticelli, Alejo, Patel, Sachin, Yuan, Wei-Chien, Fujiwara, Yuko, Li, Bin E., Orkin, Stuart H., Hormoz, Sahand, Camargo, Fernando D.
Published in Cell (11.06.2020)
Published in Cell (11.06.2020)
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Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis
Osorio, Fernando G., Rosendahl Huber, Axel, Oka, Rurika, Verheul, Mark, Patel, Sachin H., Hasaart, Karlijn, de la Fonteijne, Lisanne, Varela, Ignacio, Camargo, Fernando D., van Boxtel, Ruben
Published in Cell reports (Cambridge) (27.11.2018)
Published in Cell reports (Cambridge) (27.11.2018)
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Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer
Cheung, Priscilla, Xiol, Jordi, Dill, Michael T., Yuan, Wei-Chien, Panero, Riccardo, Roper, Jatin, Osorio, Fernando G., Maglic, Dejan, Li, Qi, Gurung, Basanta, Calogero, Raffaele A., Yilmaz, Ömer H., Mao, Junhao, Camargo, Fernando D.
Published in Cell stem cell (01.10.2020)
Published in Cell stem cell (01.10.2020)
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Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome
Santiago-Fernández, Olaya, Osorio, Fernando G., Quesada, Víctor, Rodríguez, Francisco, Basso, Sammy, Maeso, Daniel, Rolas, Loïc, Barkaway, Anna, Nourshargh, Sussan, Folgueras, Alicia R., Freije, José M. P., López-Otín, Carlos
Published in Nature medicine (01.03.2019)
Published in Nature medicine (01.03.2019)
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Lifelong multilineage contribution by embryonic-born blood progenitors
Patel, Sachin H., Christodoulou, Constantina, Weinreb, Caleb, Yu, Qi, da Rocha, Edroaldo Lummertz, Pepe-Mooney, Brian J., Bowling, Sarah, Li, Li, Osorio, Fernando G., Daley, George Q., Camargo, Fernando D.
Published in Nature (London) (23.06.2022)
Published in Nature (London) (23.06.2022)
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Defective Extracellular Pyrophosphate Metabolism Promotes Vascular Calcification in a Mouse Model of Hutchinson-Gilford Progeria Syndrome That Is Ameliorated on Pyrophosphate Treatment
Villa-Bellosta, Ricardo, Rivera-Torres, José, Osorio, Fernando G, Acín-Pérez, Rebeca, Enriquez, José A, López-Otín, Carlos, Andrés, Vicente
Published in Circulation (New York, N.Y.) (18.06.2013)
Published in Circulation (New York, N.Y.) (18.06.2013)
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Zika Virus Encoding Nonglycosylated Envelope Protein Is Attenuated and Defective in Neuroinvasion
Annamalai, Arun S, Pattnaik, Aryamav, Sahoo, Bikash R, Muthukrishnan, Ezhumalai, Natarajan, Sathish Kumar, Steffen, David, Vu, Hiep L X, Delhon, Gustavo, Osorio, Fernando A, Petro, Thomas M, Xiang, Shi-Hua, Pattnaik, Asit K
Published in Journal of virology (01.12.2017)
Published in Journal of virology (01.12.2017)
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Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid Syndrome
Puente, Xose S., Quesada, Victor, Osorio, Fernando G., Cabanillas, Rubén, Cadiñanos, Juan, Fraile, Julia M., Ordóñez, Gonzalo R., Puente, Diana A., Gutiérrez-Fernández, Ana, Fanjul-Fernández, Miriam, Lévy, Nicolas, Freije, José M.P., López-Otín, Carlos
Published in American journal of human genetics (13.05.2011)
Published in American journal of human genetics (13.05.2011)
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Effect of lyophilization on the physicochemical and rheological properties of food grade liposomes that encapsulate rutin
Lopez-Polo, Johana, Silva-Weiss, Andrea, Giménez, Begoña, Cantero-López, Plinio, Vega, Ricardo, Osorio, Fernando A.
Published in Food research international (01.04.2020)
Published in Food research international (01.04.2020)
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Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 1β Modulates Host Innate Immune Response by Antagonizing IRF3 Activation
BEURA, Lalit K, SARKAR, Saumendra N, KWON, Byungjoon, SUBRAMANIAM, Sakthivel, JONES, Clinton, PATTNAIK, Asit K, OSORIO, Fernando A
Published in Journal of Virology (01.02.2010)
Published in Journal of Virology (01.02.2010)
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Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
Osorio, Fernando G, Bárcena, Clea, Soria-Valles, Clara, Ramsay, Andrew J, de Carlos, Félix, Cobo, Juan, Fueyo, Antonio, Freije, José M P, López-Otín, Carlos
Published in Genes & development (15.10.2012)
Published in Genes & development (15.10.2012)
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