Block Copolymer Micelles in Nanomedicine Applications
Cabral, Horacio, Miyata, Kanjiro, Osada, Kensuke, Kataoka, Kazunori
Published in Chemical reviews (25.07.2018)
Published in Chemical reviews (25.07.2018)
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mRNA loading into ATP-responsive polyplex micelles with optimal density of phenylboronate ester crosslinking to balance robustness in the biological milieu and intracellular translational efficiency
Yoshinaga, Naoto, Uchida, Satoshi, Dirisala, Anjaneyulu, Naito, Mitsuru, Osada, Kensuke, Cabral, Horacio, Kataoka, Kazunori
Published in Journal of controlled release (10.02.2021)
Published in Journal of controlled release (10.02.2021)
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Bundling of mRNA strands inside polyion complexes improves mRNA delivery efficiency in vitro and in vivo
Koji, Kyoko, Yoshinaga, Naoto, Mochida, Yuki, Hong, Taehun, Miyazaki, Takuya, Kataoka, Kazunori, Osada, Kensuke, Cabral, Horacio, Uchida, Satoshi
Published in Biomaterials (01.12.2020)
Published in Biomaterials (01.12.2020)
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Bundling mRNA Strands to Prepare Nano‐Assemblies with Enhanced Stability Towards RNase for In Vivo Delivery
Yoshinaga, Naoto, Cho, Eol, Koji, Kyoko, Mochida, Yuki, Naito, Mitsuru, Osada, Kensuke, Kataoka, Kazunori, Cabral, Horacio, Uchida, Satoshi
Published in Angewandte Chemie International Edition (12.08.2019)
Published in Angewandte Chemie International Edition (12.08.2019)
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Block Copolymer Micellization as a Protection Strategy for DNA Origami
Agarwal, Nayan P., Matthies, Michael, Gür, Fatih N., Osada, Kensuke, Schmidt, Thorsten L.
Published in Angewandte Chemie International Edition (08.05.2017)
Published in Angewandte Chemie International Edition (08.05.2017)
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Single-Stranded DNA-Packaged Polyplex Micelle as Adeno-Associated-Virus-Inspired Compact Vector to Systemically Target Stroma-Rich Pancreatic Cancer
Tockary, Theofilus A, Foo, Wanling, Dirisala, Anjaneyulu, Chen, Qixian, Uchida, Satoshi, Osawa, Shigehito, Mochida, Yuki, Liu, Xueying, Kinoh, Hiroaki, Cabral, Horacio, Osada, Kensuke, Kataoka, Kazunori
Published in ACS nano (26.11.2019)
Published in ACS nano (26.11.2019)
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Bridging mRNA and Polycation Using RNA Oligonucleotide Derivatives Improves the Robustness of Polyplex Micelles for Efficient mRNA Delivery
Yoshinaga, Naoto, Uchida, Satoshi, Dirisala, Anjaneyulu, Naito, Mitsuru, Koji, Kyoko, Osada, Kensuke, Cabral, Horacio, Kataoka, Kazunori
Published in Advanced healthcare materials (01.05.2022)
Published in Advanced healthcare materials (01.05.2022)
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Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability
Dirisala, Anjaneyulu, Uchida, Satoshi, Tockary, Theofilus A., Yoshinaga, Naoto, Li, Junjie, Osawa, Shigehito, Gorantla, Lahari, Fukushima, Shigeto, Osada, Kensuke, Kataoka, Kazunori
Published in Journal of drug targeting (03.07.2019)
Published in Journal of drug targeting (03.07.2019)
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Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer
Nomoto, Takahiro, Fukushima, Shigeto, Kumagai, Michiaki, Machitani, Kaori, Arnida, Matsumoto, Yu, Oba, Makoto, Miyata, Kanjiro, Osada, Kensuke, Nishiyama, Nobuhiro, Kataoka, Kazunori
Published in Nature communications (02.04.2014)
Published in Nature communications (02.04.2014)
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Secondary‐Structure‐Driven Self‐Assembly of Reactive Polypept(o)ides: Controlling Size, Shape, and Function of Core Cross‐Linked Nanostructures
Klinker, Kristina, Schäfer, Olga, Huesmann, David, Bauer, Tobias, Capelôa, Leon, Braun, Lydia, Stergiou, Natascha, Schinnerer, Meike, Dirisala, Anjaneyulu, Miyata, Kanjiro, Osada, Kensuke, Cabral, Horacio, Kataoka, Kazunori, Barz, Matthias
Published in Angewandte Chemie International Edition (01.08.2017)
Published in Angewandte Chemie International Edition (01.08.2017)
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Encapsulation of Myoglobin in PEGylated Polyion Complex Vesicles Made from a Pair of Oppositely Charged Block Ionomers: A Physiologically Available Oxygen Carrier
Kishimura, Akihiro, Koide, Aya, Osada, Kensuke, Yamasaki, Yuichi, Kataoka, Kazunori
Published in Angewandte Chemie International Edition (13.08.2007)
Published in Angewandte Chemie International Edition (13.08.2007)
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In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle
Uchida, Satoshi, Itaka, Keiji, Uchida, Hirokuni, Hayakawa, Kentaro, Ogata, Toru, Ishii, Takehiko, Fukushima, Shigeto, Osada, Kensuke, Kataoka, Kazunori
Published in PloS one (13.02.2013)
Published in PloS one (13.02.2013)
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Targeted Polymeric Micelles for siRNA Treatment of Experimental Cancer by Intravenous Injection
Christie, R. James, Matsumoto, Yu, Miyata, Kanjiro, Nomoto, Takahiro, Fukushima, Shigeto, Osada, Kensuke, Halnaut, Julien, Pittella, Frederico, Kim, Hyun Jin, Nishiyama, Nobuhiro, Kataoka, Kazunori
Published in ACS nano (26.06.2012)
Published in ACS nano (26.06.2012)
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Effect of shear stress on structure and function of polyplex micelles from poly(ethylene glycol)-poly(L-lysine) block copolymers as systemic gene delivery carrier
Takeda, Kaori M, Yamasaki, Yuichi, Dirisala, Anjaneyulu, Ikeda, Sorato, Tockary, Theofilus A, Toh, Kazuko, Osada, Kensuke, Kataoka, Kazunori
Published in Biomaterials (01.05.2017)
Published in Biomaterials (01.05.2017)
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PEGylation of mRNA by Hybridization of Complementary PEG-RNA Oligonucleotides Stabilizes mRNA without Using Cationic Materials
Yoshinaga, Naoto, Naito, Mitsuru, Tachihara, Yoshihiro, Boonstra, Eger, Osada, Kensuke, Cabral, Horacio, Uchida, Satoshi
Published in Pharmaceutics (27.05.2021)
Published in Pharmaceutics (27.05.2021)
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In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers
Watanabe, Sumiyo, Hayashi, Kotaro, Toh, Kazuko, Kim, Hyun Jin, Liu, Xueying, Chaya, Hiroyuki, Fukushima, Shigeto, Katsushima, Keisuke, Kondo, Yutaka, Uchida, Satoshi, Ogura, Satomi, Nomoto, Takahiro, Takemoto, Hiroyasu, Cabral, Horacio, Kinoh, Hiroaki, Tanaka, Hiroyoshi Y., Kano, Mitsunobu R., Matsumoto, Yu, Fukuhara, Hiroshi, Uchida, Shunya, Nangaku, Masaomi, Osada, Kensuke, Nishiyama, Nobuhiro, Miyata, Kanjiro, Kataoka, Kazunori
Published in Nature communications (24.04.2019)
Published in Nature communications (24.04.2019)
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