Gold(III) to Ruthenium(III) Metal Exchange in Dithiocarbamato Complexes Tunes Their Biological Mode of Action for Cytotoxicity in Cancer Cells
Dalla Pozza, Maria, Orvain, Christophe, Brustolin, Leonardo, Pettenuzzo, Nicolò, Nardon, Chiara, Gaiddon, Christian, Fregona, Dolores
Published in Molecules (Basel, Switzerland) (03.07.2021)
Published in Molecules (Basel, Switzerland) (03.07.2021)
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Journal Article
Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action
Babak, Maria V, Pfaffeneder-Kmen, Martin, Meier-Menches, Samuel M, Legina, Maria S, Theiner, Sarah, Licona, Cynthia, Orvain, Christophe, Hejl, Michaela, Hanif, Muhammad, Jakupec, Michael A, Keppler, Bernhard K, Gaiddon, Christian, Hartinger, Christian G
Published in Inorganic chemistry (05.03.2018)
Published in Inorganic chemistry (05.03.2018)
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Journal Article
Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development
Soyer, Josselin, Flasse, Lydie, Raffelsberger, Wolfgang, Beucher, Anthony, Orvain, Christophe, Peers, Bernard, Ravassard, Philippe, Vermot, Julien, Voz, Marianne L, Mellitzer, Georg, Gradwohl, Gérard
Published in Development (Cambridge) (15.01.2010)
Published in Development (Cambridge) (15.01.2010)
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HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway
Spaety, Marie-Elodie, Gries, Alexandre, Badie, Amandine, Venkatasamy, Aina, Romain, Benoit, Orvain, Christophe, Yanagihara, Kazuyoshi, Okamoto, Koji, Jung, Alain C, Mellitzer, Georg, Pfeffer, Sébastien, Gaiddon, Christian
Published in Cancers (07.11.2019)
Published in Cancers (07.11.2019)
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Journal Article
Ultrasound and Transcriptomics Identify a Differential Impact of Cisplatin and Histone Deacetylation on Tumor Structure and Microenvironment in a Patient-Derived In Vivo Model of Gastric Cancer
Venkatasamy, Aina, Guerin, Eric, Blanchet, Anais, Orvain, Christophe, Devignot, Véronique, Jung, Matthieu, Jung, Alain C., Chenard, Marie-Pierre, Romain, Benoit, Gaiddon, Christian, Mellitzer, Georg
Published in Pharmaceutics (01.09.2021)
Published in Pharmaceutics (01.09.2021)
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Journal Article
The transcription factor c-Myb affects pre-mRNA splicing
Orvain, Christophe, Matre, Vilborg, Gabrielsen, Odd S.
Published in Biochemical and biophysical research communications (25.07.2008)
Published in Biochemical and biophysical research communications (25.07.2008)
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Pancreatic Islet Progenitor Cells in Neurogenin 3-Yellow Fluorescent Protein Knock-Add-On Mice
Mellitzer, Georg, Martín, Mercè, Sidhoum-Jenny, Marjorie, Orvain, Christophe, Barths, Jochen, Seymour, Philip A, Sander, Maike, Gradwohl, Gérard
Published in Molecular endocrinology (Baltimore, Md.) (01.11.2004)
Published in Molecular endocrinology (Baltimore, Md.) (01.11.2004)
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Multiple functional domains of the oncoproteins Spi-1 PU.1 and TLS are involved in their opposite splicing effects in erythroleukemic cells
DELVA, Laurent, GALLAIS, Isabelle, GUILLOUF, Christel, DENIS, Nicole, ORVAIN, Christophe, MOREAU-GACHELIN, Francoise
Published in Oncogene (27.05.2004)
Published in Oncogene (27.05.2004)
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Journal Article
Thrombin Receptor-Mediated Increase of Two Matrix Metalloproteinases, MMP-1 and MMP-3, in Human Endothelial Cells
Duhamel-Clerin, Emmanuelle, Orvain, Christophe, Lanza, Francois, Cazenave, Jean-Pierre, Klein-Soyer, Claudine
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.1997)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.1997)
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Journal Article
TiO4N2 complexes formed with 1,10-phenanthroline ligands containing a donor-acceptor hydrogen bond site: Synthesis, cytotoxicity and docking experiments
Scarpi-Luttenauer, Matthieu, Galentino, Katia, Orvain, Christophe, Cecchini, Marco, Gaiddon, Christian, Mobian, Pierre
Published in Inorganica Chimica Acta (24.09.2022)
Published in Inorganica Chimica Acta (24.09.2022)
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Journal Article
Altering relative metal-binding affinities in multifunctional Metallochaperones for mutant p53 reactivation
Kwan, Kalvin, Castro-Sandoval, Omar, Ma, Benjamin, Martelino, Diego, Saffari, Ashkan, Liu, Xi Lan, Orvain, Christophe, Mellitzer, Georg, Gaiddon, Christian, Storr, Tim
Published in Journal of inorganic biochemistry (01.02.2024)
Published in Journal of inorganic biochemistry (01.02.2024)
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Journal Article
Front Cover: Synthesis of Cytotoxic Iron‐Containing Macrocycles Through Unexpected C(sp2)−C(sp2) Bonds Formation (Eur. J. Inorg. Chem. 23/2023)
Torres‐Gutiérrez, Carolina, Estrada‐Montaño, Aldo S., Orvain, Christophe, Mellitzer, Georg, Gaiddon, Christian, Le Lagadec, Ronan
Published in European journal of inorganic chemistry (11.08.2023)
Published in European journal of inorganic chemistry (11.08.2023)
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Journal Article
The unfolded protein response-glutathione metabolism axis: A novel target of a cycloruthenated complexes bypassing tumor resistance mechanisms
Riegel, Gilles, Orvain, Christophe, Recberlik, Sevda, Spaety, Marie-Elodie, Poschet, Gernot, Venkatasamy, Aina, Yamamoto, Masami, Nomura, Sachiyo, Tsukamoto, Tetsyua, Masson, Murielle, Gross, Isabelle, Le Lagadec, Ronan, Mellitzer, Georg, Gaiddon, Christian
Published in Cancer letters (31.03.2024)
Published in Cancer letters (31.03.2024)
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Journal Article
Bifunctional ligand design for modulating mutant p53 aggregation in cancer
Miller, Jessica J, Blanchet, Anaïs, Orvain, Christophe, Nouchikian, Lucienne, Reviriot, Yasmin, Clarke, Ryan M, Martelino, Diego, Wilson, Derek, Gaiddon, Christian, Storr, Tim
Published in Chemical science (Cambridge) (14.12.2019)
Published in Chemical science (Cambridge) (14.12.2019)
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Journal Article
Multifunctional metallochaperone modifications for targeting subsite cavities in mutant p53-Y220C
Miller, Jessica J., Kwan, Kalvin, Blanchet, Anaïs, Orvain, Christophe, Mellitzer, Georg, Smith, Jason, Lento, Cristina, Nouchikian, Lucienne, Omoregbee-Leichnitz, Sabrina, Sabatou, Marie, Wilson, Derek, Gaiddon, Christian, Storr, Tim
Published in Journal of inorganic biochemistry (01.05.2023)
Published in Journal of inorganic biochemistry (01.05.2023)
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Journal Article
Synthesis of Cytotoxic Iron‐Containing Macrocycles Through Unexpected C(sp2)−C(sp2) Bonds Formation
Torres‐Gutiérrez, Carolina, Estrada‐Montaño, Aldo S., Orvain, Christophe, Mellitzer, Georg, Gaiddon, Christian, Le Lagadec, Ronan
Published in European journal of inorganic chemistry (11.08.2023)
Published in European journal of inorganic chemistry (11.08.2023)
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Journal Article
Trans-C versus Cis-C thermally induced isomerisation of a terpyridine adduct of cytotoxic cycloruthenated compound
Ali, Moussa, Hamada, Adel, Habbita, Houda, Weckbach, Jennifer, Orvain, Christophe, Gaiddon, Christian, Pfeffer, Michel
Published in Journal of organometallic chemistry (15.09.2017)
Published in Journal of organometallic chemistry (15.09.2017)
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Quest for a stable Cu-ligand complex with a high catalytic activity to produce reactive oxygen species
Bouraguba, Merwan, Schmitt, Adeline M, Yelisetty, Venkata Suseela, Vileno, Bertrand, Melin, Frédéric, Glattard, Elise, Orvain, Christophe, Lebrun, Vincent, Raibaut, Laurent, Ilbert, Marianne, Bechinger, Burkhard, Hellwig, Petra, Gaiddon, Christian, Sour, Angélique, Faller, Peter
Published in Metallomics (02.05.2024)
Published in Metallomics (02.05.2024)
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Monomeric Ti(iv)-based complexes incorporating luminescent nitrogen ligands: synthesis, structural characterization, emission spectroscopy and cytotoxic activities
Khalil, Georges, Orvain, Christophe, Fang, Lu, Barloy, Laurent, Chaumont, Alain, Gaiddon, Christian, Henry, Marc, Kyritsakas, Nathalie, Mobian, Pierre
Published in Dalton transactions : an international journal of inorganic chemistry (2016)
Published in Dalton transactions : an international journal of inorganic chemistry (2016)
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